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Just Tired
Hi Everyone - this is such a valuable community. I just wanted to vent a little. Are any parents on this journey just feeling tired? We have weathered the nasty teachers, the disinterested teachers, the play therapy, the behavior therapy, the unconventional treatments, the medications, the school
Hi Everyone - this is such a valuable community. I just wanted to vent a little. Are any parents on this journey just feeling tired? We have weathered the nasty teachers, the disinterested teachers, the play therapy, the behavior therapy, the unconventional treatments, the medications, the school
Uptowngirl12121
in
CHADD's ADHD Parents Together
2 months ago
Hormone Replacement Therapy (HRT)
I just recently read some interesting studies that suggest HRT could help us PD people with our symptoms? I know for some HRT is controversial. And maybe I am at the point of desperation, but should I just be asking my GP for an HRT patch? Have any of you had any experience with HRT. Is one delivery
I just recently read some interesting studies that suggest HRT could help us PD people with our symptoms? I know for some HRT is controversial. And maybe I am at the point of desperation, but should I just be asking my GP for an HRT patch? Have any of you had any experience with HRT. Is one delivery
PalmSprings
in
Cure Parkinson's
9 months ago
Rheumatoid, Peri-Menopause, HRT
I am 54 and have had RA for 34 years. I am at the end stage of perimenopause, and close to transitioning to Menopause. The RA feels worse. My joints are so achy even my muscles hurt at times. Anyone suggestions from experienced ladies. Does HRT help? My current medication list is Humira 40 by weekly
I am 54 and have had RA for 34 years. I am at the end stage of perimenopause, and close to transitioning to Menopause. The RA feels worse. My joints are so achy even my muscles hurt at times. Anyone suggestions from experienced ladies. Does HRT help? My current medication list is Humira 40 by weekly
ragurl
in
NRAS
9 months ago
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The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer's disease May 2024
- https://www.researchgate.net/publication/380600451_The_40_Hz_flickering_light_restores_synaptic_plasticity_and_mitochondrial_phenotype_in_experimental_model_of_Alzheimer
Bolt_Upright
in
Cure Parkinson's
2 months ago
Hip replacement date
Hello All, It’s been a long time since I’ve been on here, I finally got into sheltered housing last April & got a lovely little bungalow I’m over the moon with. It was in very good content with decent carpets curtains, and blinds left & got a decorating/other grant from the council that I wasn’t expecting
Hello All, It’s been a long time since I’ve been on here, I finally got into sheltered housing last April & got a lovely little bungalow I’m over the moon with. It was in very good content with decent carpets curtains, and blinds left & got a decorating/other grant from the council that I wasn’t expecting
Shamrockgirl
in
NRAS
6 months ago
Moving forward
Before my diagnosis, I had various symptoms that I could not control, and afterward would lose parts of my memories, it was people's names and events later I had a seizure but sometimes in my sleep. It was either when I was fully awake and alert and I could see my surroundings but then if I did have
Before my diagnosis, I had various symptoms that I could not control, and afterward would lose parts of my memories, it was people's names and events later I had a seizure but sometimes in my sleep. It was either when I was fully awake and alert and I could see my surroundings but then if I did have
mavem100
in
Functional Neurological Disorder - FND Hope
2 months ago
HRT & Anxiety
hI am looking for advice am struggling at the moment with side effects from HRT patches, am only on oestrogen as have no womb. Headaches, nausea and more recent anxiety, am only on a low dose and been on for nearly 4weks. I feel am going crazy, every patch change my arms and hands feel really
hI am looking for advice am struggling at the moment with side effects from HRT patches, am only on oestrogen as have no womb. Headaches, nausea and more recent anxiety, am only on a low dose and been on for nearly 4weks. I feel am going crazy, every patch change my arms and hands feel really
Bassem1979
in
Menopause and Perimenopause Support
9 months ago
not diagnosed yet but need pain tips
Hi can anyone give me any tips on dealing with pain please? I’m on a years waiting list now with a gyno to check for endo and ando. I may be going on to HRT soon for the peri menopause. I’ve tried different pain killers, exercise, meditation and mint tea. Nothing works. The pain is only 5 days
Hi can anyone give me any tips on dealing with pain please? I’m on a years waiting list now with a gyno to check for endo and ando. I may be going on to HRT soon for the peri menopause. I’ve tried different pain killers, exercise, meditation and mint tea. Nothing works. The pain is only 5 days
Citrusheights79
in
Endometriosis UK
9 months ago
B.A.T and Provenge trial.
After 9mo the Arv-766 started to fail. I will be starting a combination therapy trial through Yale using B.A.T. And Provenge. This is the first time I’ve heard of such a combo. There are only 6 of us in this trial. Is there anyone else on this trial or have any experience with using both treatments
After 9mo the Arv-766 started to fail. I will be starting a combination therapy trial through Yale using B.A.T. And Provenge. This is the first time I’ve heard of such a combo. There are only 6 of us in this trial. Is there anyone else on this trial or have any experience with using both treatments
No_stone_unturned
in
Advanced Prostate Cancer
2 months ago
HOrmone Replacement Therepy
I have wondered for a while whether men also lose hormones as they age and whether patches would be beneficial. I am a complete layman, so may be talking rubbish . I read on one post that Parkinsons can give people hot flushes, so this got me thinking. Have there been any studies please?
I have wondered for a while whether men also lose hormones as they age and whether patches would be beneficial. I am a complete layman, so may be talking rubbish . I read on one post that Parkinsons can give people hot flushes, so this got me thinking. Have there been any studies please?
Jo692
in
Cure Parkinson's
9 months ago
school anxiety
I’m in speech therapy grad school, something I’ve worked towards for a VERY long time. I made so many sacrifices to be here and I got a C in a clinical experience. In my program you have to get a B to pass and move forward. I have to redo this clinical experience and any time I have a meeting for it
I’m in speech therapy grad school, something I’ve worked towards for a VERY long time. I made so many sacrifices to be here and I got a C in a clinical experience. In my program you have to get a B to pass and move forward. I have to redo this clinical experience and any time I have a meeting for it
Pupsandpeonies
in
Anxiety and Depression Support
2 months ago
Supporting evidence for PIP
I’m ploughing through the online form and it keeps saying about supporting evidence. I was diagnosed in 2021 by my then GP in the midlands over the Covid period - so not many doctor visits. Not much prescribed, using paracetamol and/or ibuprofen as and when necessary. Basically have been self-managing
I’m ploughing through the online form and it keeps saying about supporting evidence. I was diagnosed in 2021 by my then GP in the midlands over the Covid period - so not many doctor visits. Not much prescribed, using paracetamol and/or ibuprofen as and when necessary. Basically have been self-managing
Gulfstream_Maggie
in
Fibromyalgia Action UK
2 months ago
List of good Genetic Tests in Homologous Recombination Deficiency in PCa and the Mechanisms of Resistance to PARP Inhibitors
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
I was searching RAD50 and PARPinhibitors and since i am going for a high risk genetic consult i came across this good explanation of different genetic testing. Title of article:
Homologous Recombination Deficiency in Ovarian, Breast, Colorectal, Pancreatic, Non-Small Cell Lung and Prostate Cancers
KocoPr
in
Advanced Prostate Cancer
2 months ago
given up
Hello, I was wondering if anyone could possibly help me with some advice. Unfortunately, because I am under 60 years of age, I have basically been told I will not get a knee replacement until I am 60 or over, but I am now unable to weigh bare because of my knees, and I do mean unable to even put any
Hello, I was wondering if anyone could possibly help me with some advice. Unfortunately, because I am under 60 years of age, I have basically been told I will not get a knee replacement until I am 60 or over, but I am now unable to weigh bare because of my knees, and I do mean unable to even put any
Jinnty89
in
My EXI Community
6 months ago
BLA for Subcutaneous Nivolumab Accepted by the FDA for Advanced/Metastatic Solid Tumors
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
A biologics license application (BLA) has been accepted by the FDA seeking approval of nivolumab (Opdivo) co-formulated with Halozyme’s proprietary recombinant human hyaluronidase (rHuPH20; subcutaneous nivolumab) for adult patients with solid tumors eligible for previously approved nivolumab indications
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
Thank you Angela for sharing your story!
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
SkcinHQ
Partner
in
Skin Cancer UK
2 months ago
Side effects on combination therapy : thyroxine and T3
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
TheaW
in
Thyroid UK
2 months ago
25th Park Run!
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
It may not seem like a big deal but it is to me. I couldn't walk til I was 4, have had 3 hip replacements and back surgery. I never ran before I was 69 and now I've done 25 Park runs. I'm feeling very proud of myself. I even knocked a minute off last week's time! It was a glorious morning. I just took
Bruch1
Graduate
in
Couch to 5K
6 months ago
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
God_Loves_Me
in
Advanced Prostate Cancer
2 months ago
constipation leading to Pelvic Floor dysfunction
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
Profound15
in
IBS Network
2 months ago
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