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CRISPR Identifies New Genes as Drivers of Prostate Cancer Metastasis
Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use of CRISPR technology not only facilitated the discovery of the genes but also opened potential new avenues for targeted cancer therapies to prevent metastasis
Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use of CRISPR technology not only facilitated the discovery of the genes but also opened potential new avenues for targeted cancer therapies to prevent metastasis
No_stone_unturned
in
Advanced Prostate Cancer
1 month ago
Is this decision right for me
I had a PSMA pet scan on 7/16/2024. The result shows a single tumor in my left lung measuring 8mm. My MO wants me to have the tumor radiated and monitor the PSA and its doubling time. A little background, I'm just short of 83 years old. I had prostatectomy in 2009, PSA undetectable until 2017. I had
I had a PSMA pet scan on 7/16/2024. The result shows a single tumor in my left lung measuring 8mm. My MO wants me to have the tumor radiated and monitor the PSA and its doubling time. A little background, I'm just short of 83 years old. I had prostatectomy in 2009, PSA undetectable until 2017. I had
old64horn
in
Advanced Prostate Cancer
1 month ago
Can Exercise Help People with Parkinson’s Disease? 5 Things to Know
According to a study that tracked 237 patients over a five-year period, those with early-stage Parkinson’s disease who were more active had better physical outcomes than less active people with the disease. “Higher physical activity levels were strongly associated with better functioning in activities
According to a study that tracked 237 patients over a five-year period, those with early-stage Parkinson’s disease who were more active had better physical outcomes than less active people with the disease. “Higher physical activity levels were strongly associated with better functioning in activities
Farooqji
in
Cure Parkinson's
1 month ago
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There's Hope
Being a dialysis patient can have its difficulty, but when you have dual diagnosis like being a diabetic sometimes it feels like all he'll breaks through. But I decided to reach out to my medical team and I got the support I needed as well as understanding my situation. I have a plan that I and my
Being a dialysis patient can have its difficulty, but when you have dual diagnosis like being a diabetic sometimes it feels like all he'll breaks through. But I decided to reach out to my medical team and I got the support I needed as well as understanding my situation. I have a plan that I and my
Quita55
in
Kidney Dialysis
1 month ago
RUQ of abdomen
Can someone have an ache in the right upper quadrant of their abdomen without it being something seriously wring with the liver like cirrhosis? Thanks, Terry
Can someone have an ache in the right upper quadrant of their abdomen without it being something seriously wring with the liver like cirrhosis? Thanks, Terry
ToughToes
in
British Liver Trust
1 month ago
please help
hello I’ve been on here a few times now, at first it started being my TSH and T3 suggesting hyperthyroidism, I was then referred to an endocrinologist and retested and that was then fine however my cortisol was low at 220 so I had a SST yesterday and the results have come back as below which they have
hello I’ve been on here a few times now, at first it started being my TSH and T3 suggesting hyperthyroidism, I was then referred to an endocrinologist and retested and that was then fine however my cortisol was low at 220 so I had a SST yesterday and the results have come back as below which they have
Lollipop93
in
Thyroid UK
1 month ago
Considering a change of dialysis centers
So, my nephrologist just up and left. I'm sure there was more going on behind the scenes than I'm aware of, but it was so sudden for me. He was also the consulting MD at the dialysis clinic. I'm not worried about finding another nephro, though. The nephrology department I deal with is a crack team
So, my nephrologist just up and left. I'm sure there was more going on behind the scenes than I'm aware of, but it was so sudden for me. He was also the consulting MD at the dialysis clinic. I'm not worried about finding another nephro, though. The nephrology department I deal with is a crack team
PeaB4YouGo
in
Kidney Dialysis
1 month ago
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease
A mouse study, and just an abstract, but it is pro-curcumin and so am I so I am sharing it:
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease 2024
https://pubmed.ncbi.nlm.nih.gov/39006191/
Background:
A mouse study, and just an abstract, but it is pro-curcumin and so am I so I am sharing it:
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease 2024
https://pubmed.ncbi.nlm.nih.gov/39006191/
Background:
Bolt_Upright
in
Cure Parkinson's
1 month ago
Stuff to Do Before Comprehensive Arthroscopic Shoulder Surgery
Hi all, I'm scheduling for aka Comprehensive Arthroscopic Shoulder Surgery (Rotator Cuff Repair, Subacromial Decompression, and Shoulder Tenotomy). Fun! I live alone. I've arranged for cleaning, for grocery and food delivery, for errand running. I will try to schedule physical therapy and gather meds
Hi all, I'm scheduling for aka Comprehensive Arthroscopic Shoulder Surgery (Rotator Cuff Repair, Subacromial Decompression, and Shoulder Tenotomy). Fun! I live alone. I've arranged for cleaning, for grocery and food delivery, for errand running. I will try to schedule physical therapy and gather meds
Jimmber
in
PMRGCAuk
1 month ago
results of nail biopsy
At the end of last week I got my results of my nail biopsies. It is no fungus, no infection and best of all no cancer. They do not know what it actually is despite using numerous tests. A very happy outcome, as all medics seen in the process suspected subungual melanoma. I can live with not knowing
At the end of last week I got my results of my nail biopsies. It is no fungus, no infection and best of all no cancer. They do not know what it actually is despite using numerous tests. A very happy outcome, as all medics seen in the process suspected subungual melanoma. I can live with not knowing
artydutch
in
MPN Voice
1 month ago
Stem Cell Therapy For Parkinson's Disease - Ozzy Osbourne experience
Ozzy Osbourne has been plagued with a number of health problems in the last several years, including a Parkinson's Disease diagnosis. On his radio show, the rock icon opened up about receiving stem cell therapy to help regulate the disease. “I’ve just come back from the doctor after having some stem
Ozzy Osbourne has been plagued with a number of health problems in the last several years, including a Parkinson's Disease diagnosis. On his radio show, the rock icon opened up about receiving stem cell therapy to help regulate the disease. “I’ve just come back from the doctor after having some stem
Farooqji
in
Cure Parkinson's
1 month ago
just diagnosed with cirrhosis
I was just diagnosed with cirrhosis 6 weeks ago. My fibroscan score was 14.1 The endoscopy , blood tests and ultrasound did not show bad results. I started getting these aches in my liver area after I had the fibroscan. Is this normal. Im afraid it started something.
I was just diagnosed with cirrhosis 6 weeks ago. My fibroscan score was 14.1 The endoscopy , blood tests and ultrasound did not show bad results. I started getting these aches in my liver area after I had the fibroscan. Is this normal. Im afraid it started something.
Maddog2024
in
British Liver Trust
1 month ago
Question
Was diagnosed with stage 4 metastatic prostate cancer with several mets to the bones and a Gleason score of 10. This was in January 2023. I have been on darolutamide and relugolix since then and also 6 rounds of docetaxol. Everything was good until recently with an increase in PSA from non detectable
Was diagnosed with stage 4 metastatic prostate cancer with several mets to the bones and a Gleason score of 10. This was in January 2023. I have been on darolutamide and relugolix since then and also 6 rounds of docetaxol. Everything was good until recently with an increase in PSA from non detectable
lovepockets
in
Advanced Prostate Cancer
1 month ago
One last push ..please...help for my Dad. NHS treatments no longer viable - Pca stage 4.
Guys...do not know how to connect this post to my previous ones..sorry. I'm also all over the place, forgive my ramblings! I have finally gotten hold of Dad's records. Nothing more NHS can do, so am looking at Turkey for Lu 177. I know this is an option, but want to literally exhaust anything in the
Guys...do not know how to connect this post to my previous ones..sorry. I'm also all over the place, forgive my ramblings! I have finally gotten hold of Dad's records. Nothing more NHS can do, so am looking at Turkey for Lu 177. I know this is an option, but want to literally exhaust anything in the
kikinini
in
Advanced Prostate Cancer
1 month ago
adrenal insufficiency
hi I have a question about changing medication. I have GCA (3 years) but doing well and have reduced pred to 3mg. My endocrinologist wants to change the prednisilone to cortisone twice a day, 10mg am and 5mg pm in order to help kick start the adrenals. I've had the short Synacthen test twice now and
hi I have a question about changing medication. I have GCA (3 years) but doing well and have reduced pred to 3mg. My endocrinologist wants to change the prednisilone to cortisone twice a day, 10mg am and 5mg pm in order to help kick start the adrenals. I've had the short Synacthen test twice now and
Luciejane
in
PMRGCAuk
1 month ago
Exercise therapy developed by Korean Organization
Researchers in Korea have developed an at-home exercise program to help patients suffering from Parkinson’s disease improve their motor function and reduce depression. The National Institute of Health of the Korea Disease Control and Prevention Agency said Tuesday that the safety and suitability
Researchers in Korea have developed an at-home exercise program to help patients suffering from Parkinson’s disease improve their motor function and reduce depression. The National Institute of Health of the Korea Disease Control and Prevention Agency said Tuesday that the safety and suitability
Farooqji
in
Cure Parkinson's
1 month ago
Pluvicto and Renal Issues
I have had normal physical impact from my 4 previous Pluvicto injections: fatigue, reduced appitite, and additional sleep requirements. My fifth injection, 10 days ago, however, resulted in me being bedridden most of the time, no appetite, excessive sleep, stomach pain, and, and what I believe, severe
I have had normal physical impact from my 4 previous Pluvicto injections: fatigue, reduced appitite, and additional sleep requirements. My fifth injection, 10 days ago, however, resulted in me being bedridden most of the time, no appetite, excessive sleep, stomach pain, and, and what I believe, severe
GDG1
in
Advanced Prostate Cancer
1 month ago
Metastatic Prostate Cancer
Just started Zytiga, prednisone and hormone shots for recurrent prostate cancer that has returned and spread to lungs. Just wondering if anyone else is taking these drugs and what their experience has been with side effects the first month or so. Thanks.
Just started Zytiga, prednisone and hormone shots for recurrent prostate cancer that has returned and spread to lungs. Just wondering if anyone else is taking these drugs and what their experience has been with side effects the first month or so. Thanks.
wpeebles
in
Advanced Prostate Cancer
1 month ago
What treatment next as PSA increasing on Daroludamide & Lupron
My PSA is increasing after a year on Daroludamide and Lupron.
Questions:
1) can the Daroludamide be increased?
2) what is the next treatment after this to reduce PSA?
Sincere thanks.
My PSA is increasing after a year on Daroludamide and Lupron.
Questions:
1) can the Daroludamide be increased?
2) what is the next treatment after this to reduce PSA?
Sincere thanks.
mklc
in
Advanced Prostate Cancer
1 month ago
Researchers discover new cellular mechanisms in Parkinson’s disease (technical)
“Our studies show that multiple pathways are perturbed in the disease and so we think that rescuing multiple pathways at once is essential for disease modification.” “We’re not saying that [alpha-synuclein aggregation] is not important, but we’re showing that there are other proteins and RNA inclusions
“Our studies show that multiple pathways are perturbed in the disease and so we think that rescuing multiple pathways at once is essential for disease modification.” “We’re not saying that [alpha-synuclein aggregation] is not important, but we’re showing that there are other proteins and RNA inclusions
jeffreyn
in
Cure Parkinson's
1 month ago
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