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Why do we use IFN-α vs IFN-β? Might IFN-β be preferred?
[i] (IFN-α with tamoxifen is also a possibility)[/i] -[i]Another proposed combo:[/i]
Combination
Therapy
of Tamoxifen, Retinoic Acid, and rIFN-B -[i]IFN-α is our best bet for now but:[/i] We can conclude that stem-cell targeted therapy with rIFN-a2 will be the cornerstone in the future treatment
[i] (IFN-α with tamoxifen is also a possibility)[/i] -[i]Another proposed combo:[/i]
Combination
Therapy
of Tamoxifen, Retinoic Acid, and rIFN-B -[i]IFN-α is our best bet for now but:[/i] We can conclude that stem-cell targeted therapy with rIFN-a2 will be the cornerstone in the future treatment
EPguy
in
MPN Voice
1 year ago
Treatment - radiation vs. surgery
Hello, I posted previously after I was first diagnosed and had some great feedback. I wanted to try once more after being able to spend the past couple of months researching and trying to make the best treatment decision moving forward. For anyone similarly affected, it might help to reflect on what
Hello, I posted previously after I was first diagnosed and had some great feedback. I wanted to try once more after being able to spend the past couple of months researching and trying to make the best treatment decision moving forward. For anyone similarly affected, it might help to reflect on what
TonyTx
in
Prostate Cancer Network
7 months ago
Prostap/tibolone - regal study
Hi all, I'm 1 week into prostap and tibolone as part of the reval study and I'm not coping well. I dont want to be another horror story on the internet so to keep it brief my main concern is constant nausea (but I cant function) and worsened allergies (and I have a history of anaphylaxis as it is).
Hi all, I'm 1 week into prostap and tibolone as part of the reval study and I'm not coping well. I dont want to be another horror story on the internet so to keep it brief my main concern is constant nausea (but I cant function) and worsened allergies (and I have a history of anaphylaxis as it is).
Ash24601
in
Endometriosis UK
8 months ago
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Thyroiditis
Hi, I am wondering any has had a similar running with painless thyroiditis. Nov 2021 I caught C-19. February 2022 I started feeling woozy a very strange feeling blood tests showed I was aneamic. So I was taking iron, but panic attacks, high heart rate were getting worse. In May 2022 I was unable to
Hi, I am wondering any has had a similar running with painless thyroiditis. Nov 2021 I caught C-19. February 2022 I started feeling woozy a very strange feeling blood tests showed I was aneamic. So I was taking iron, but panic attacks, high heart rate were getting worse. In May 2022 I was unable to
Dizzy2016
in
Thyroid UK
9 months ago
steel hardware in spine and ADT and Radiation
We are off to Mayo Phoenix tomorrow for three month post RARP check up. Not sure what will be suggested, but definitely looking for referrals to oncology and radiology oncology, due to his high/very high risk findings and pathology. He has two steel rods and 9 screws in his thoracic and lumbar spine
We are off to Mayo Phoenix tomorrow for three month post RARP check up. Not sure what will be suggested, but definitely looking for referrals to oncology and radiology oncology, due to his high/very high risk findings and pathology. He has two steel rods and 9 screws in his thoracic and lumbar spine
Lokicliff
in
Advanced Prostate Cancer
8 months ago
BCR May Not Be a Strong Surrogate End Point for Prostate Cancer Survival
A new study, below [1] & [2]. In 2004 I came across old studies that showed that ADT promotes changes to the androgen receptor [AR] environment. At diagnosis, the AR is invariably "wild type". When ADT failed, AR gene amplification was common. True mutations were rare. {This was sufficient for
A new study, below [1] & [2]. In 2004 I came across old studies that showed that ADT promotes changes to the androgen receptor [AR] environment. At diagnosis, the AR is invariably "wild type". When ADT failed, AR gene amplification was common. True mutations were rare. {This was sufficient for
pca2004
in
Fight Prostate Cancer
8 months ago
Insurance Rant
Sorry folks, I just need to sound off about the way insurance companies treat us in their medical screening. Generally I feel quite good, yes I have had challenges and times when I have been very poorly but today, this month I am pretty much cancer free and I feel like a survivor. But the insurance
Sorry folks, I just need to sound off about the way insurance companies treat us in their medical screening. Generally I feel quite good, yes I have had challenges and times when I have been very poorly but today, this month I am pretty much cancer free and I feel like a survivor. But the insurance
Lyndy
in
My Ovacome
11 months ago
ADT + darolutamide + docetaxel (ARASENS trial) has anyone tried it?
Hi people! My first update since the diagnosis. After less than one month of regrouping and ADT only (decapeptyl - triptotrelin, which got my PSA from 70 to 15), my MO decided to do the ARASENS trial triplet (with my full approval, I was going to propose him this protocol). Has anyone tried it?
Hi people! My first update since the diagnosis. After less than one month of regrouping and ADT only (decapeptyl - triptotrelin, which got my PSA from 70 to 15), my MO decided to do the ARASENS trial triplet (with my full approval, I was going to propose him this protocol). Has anyone tried it?
Maxone73
in
Advanced Prostate Cancer
8 months ago
HRT patches
HI My doctor has asked me to consider HRT patches to help with my tiredness, aching joints , hot flushes and belly fat gain. I always thought that HRT can cause weight gain. Does any one have any experience of these patches they can share with me please. I'm so confused and i dont want to start something
HI My doctor has asked me to consider HRT patches to help with my tiredness, aching joints , hot flushes and belly fat gain. I always thought that HRT can cause weight gain. Does any one have any experience of these patches they can share with me please. I'm so confused and i dont want to start something
Gyp101
in
Women's Health
8 months ago
Arrythmias on Zytiga
i am finishing my19th month of degarelix and abiraterone. Over the past 3-4 months pvc/arrythmias have gotten more frequent progressing to daily. In fact at my last two injections the nurses have asked if I have a history of arrythmias given my HR was so irradict. So my question is do I request a dose
i am finishing my19th month of degarelix and abiraterone. Over the past 3-4 months pvc/arrythmias have gotten more frequent progressing to daily. In fact at my last two injections the nurses have asked if I have a history of arrythmias given my HR was so irradict. So my question is do I request a dose
Oceankayaker
in
Advanced Prostate Cancer
8 months ago
New to all this, please help with test results
People on the Hypothyroid UK forum have suggested that I join this forum because of some test results that I received yesterday. Long story short, I've finally been diagnosed with hypothyroid, but I'm still having awful problems with my memory, attention, concentration, finding words and ability to
People on the Hypothyroid UK forum have suggested that I join this forum because of some test results that I received yesterday. Long story short, I've finally been diagnosed with hypothyroid, but I'm still having awful problems with my memory, attention, concentration, finding words and ability to
TheSnufkin
in
Pernicious Anaemia Society
8 months ago
HRT and Alzheimer’s after 1 year
I found this article about HRT and Alzheimer’s and know a lot of us ladies are on them …. What is your thoughts on this article?
I found this article about HRT and Alzheimer’s and know a lot of us ladies are on them …. What is your thoughts on this article?
Batty1
in
Thyroid UK
8 months ago
from undetectable to 0.02
I have been undetectable for 3.25 years and today it came back at 0.02. My bio is up to date. We ran the test at the exact same lab as always and in 2 days I am flying back to my Sarasota home from Milwaukee and was wondering which lab is recommended for 2 digit accuracy? I know Labcorp only does 1
I have been undetectable for 3.25 years and today it came back at 0.02. My bio is up to date. We ran the test at the exact same lab as always and in 2 days I am flying back to my Sarasota home from Milwaukee and was wondering which lab is recommended for 2 digit accuracy? I know Labcorp only does 1
Peppertree602
in
Advanced Prostate Cancer
8 months ago
Aspirin trials
I have recently finished hormone therapy, last 3 monthly injection April 2023. Good result so far with PSA at <0.01. Met with my Oncologist today and he said there were trials using aspirin as a potential drug to reduce potential recurrence. Has anyone come across this and, even though the results
I have recently finished hormone therapy, last 3 monthly injection April 2023. Good result so far with PSA at <0.01. Met with my Oncologist today and he said there were trials using aspirin as a potential drug to reduce potential recurrence. Has anyone come across this and, even though the results
Runner1957
in
Prostate Cancer Network
8 months ago
Latest blood results - any ideas?
Hello Everyone, Here are my most recent BH results obtained as per the forum guidelines - the last test I did was about 3 months ago. Cortisol Following my very low Regenerus cortisol results, I've been on Adrenavive 2 for about 4 weeks now, no digestive or other problems. I've been working upwards
Hello Everyone, Here are my most recent BH results obtained as per the forum guidelines - the last test I did was about 3 months ago. Cortisol Following my very low Regenerus cortisol results, I've been on Adrenavive 2 for about 4 weeks now, no digestive or other problems. I've been working upwards
Sneedle
in
Thyroid UK
8 months ago
endo symptoms on hormonal therapy
hello, im just wondering for those who are on any kind of hormone therapy eg pill, IUD and DONT have period because of this what are your symptoms?? I don’t have periods anymore but wondering what kind of Endo symptoms people experience when they don’t menstruate. Been told by a DR I can’t have
hello, im just wondering for those who are on any kind of hormone therapy eg pill, IUD and DONT have period because of this what are your symptoms?? I don’t have periods anymore but wondering what kind of Endo symptoms people experience when they don’t menstruate. Been told by a DR I can’t have
PBGV24
in
Endometriosis UK
8 months ago
Heat or Light Therapy
Does anyone use Infrared heat or Red Light Therapy (RLT) and has it changed anything for you? I have not tried either one. I do use the sauna after each swim workout: ice cold shower, 15 min sauna, ice cold shower, sauna, shower. This really shocks my system and I feel that it is helpful to really
Does anyone use Infrared heat or Red Light Therapy (RLT) and has it changed anything for you? I have not tried either one. I do use the sauna after each swim workout: ice cold shower, 15 min sauna, ice cold shower, sauna, shower. This really shocks my system and I feel that it is helpful to really
Gym-rat
in
Advanced Prostate Cancer
11 months ago
HRT and RLS
Hi, I just saw a reply on a post where Sue talked about HRT being a possible trigger. Are there any safe options? I am currently on Femeton and have just been put on a higher dose because of menopause symptoms. I’m wondering now if this is part of the problem. I would probably be suicidal if I
Hi, I just saw a reply on a post where Sue talked about HRT being a possible trigger. Are there any safe options? I am currently on Femeton and have just been put on a higher dose because of menopause symptoms. I’m wondering now if this is part of the problem. I would probably be suicidal if I
loops1207
in
Restless Legs Syndrome
8 months ago
Starting B12 injections
Hi I am hypothyroid, on Armour Thyroid but still dog tired all the time. I’m on HRT and I have horrible peripheral neuropathy in my feet and lower legs. I can’t walk well or for long at all. My gait feels really off. I’m stiff and have no muscular strength in my legs anymore so crouching down is impossible
Hi I am hypothyroid, on Armour Thyroid but still dog tired all the time. I’m on HRT and I have horrible peripheral neuropathy in my feet and lower legs. I can’t walk well or for long at all. My gait feels really off. I’m stiff and have no muscular strength in my legs anymore so crouching down is impossible
FancyPants54
in
Pernicious Anaemia Society
8 months ago
Enzalutamide (Xtandi): Start at half standard dose to extend efficacy time span?
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
Good Morning AllI was disgnosed 6 years ago with oligometastic prostate cancer Gleeson 8, PSA 22. Since January 2018 I have been on ADT, had docetaxel chemo in April 2018, radiotherapy to the prostate, seminal vessel and pelvis in November 2018 when PSA dropped to <0.1. PSMA PET CT scan in March 2019
KGU1
in
Advanced Prostate Cancer
8 months ago
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