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Senescent neutrophils and their subsequent impact on tumor progression and therapy resistance
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
cigafred
in
Fight Prostate Cancer
1 year ago
Atrial Fibrillation (AF) Fact File
Atrial fibrillation (also referred to as AF) is an abnormality in the rhythm of the heart (an arrhythmia). For a full overview of AF from types of AF, diagnosis to managing symptoms, medication, cardioversion, catheter ablation …. And much more! Have you read our Atrial Fibrillation (AF) Fact File?
Atrial fibrillation (also referred to as AF) is an abnormality in the rhythm of the heart (an arrhythmia). For a full overview of AF from types of AF, diagnosis to managing symptoms, medication, cardioversion, catheter ablation …. And much more! Have you read our Atrial Fibrillation (AF) Fact File?
TracyAdmin
Partner
in
Atrial Fibrillation Support
3 months ago
fatigue wit afib. Will ablation help?
I have had increased fatigue and less ability to exercise since I have had afib and aflutter with high heart rate the last 7 years. I am finally having an ablation in August. Has anyone found it helps with fatigue. I really can’t make it through a day now without a nap, and must sleep at least 7-9 hrs
I have had increased fatigue and less ability to exercise since I have had afib and aflutter with high heart rate the last 7 years. I am finally having an ablation in August. Has anyone found it helps with fatigue. I really can’t make it through a day now without a nap, and must sleep at least 7-9 hrs
37Polly
in
Atrial Fibrillation Support
3 months ago
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Will it, won’t it?
My AFib occurs roughly every 3-5 weeks and ranging from 12-30 hrs. I am going into hospital next Friday 26th for surgery under an GA and have to take my last apixaban Tuesday evening. Pre op said it was unlikely surgery would go ahead if I was in Afib. I’ve been waiting a year for surgery so I obviously
My AFib occurs roughly every 3-5 weeks and ranging from 12-30 hrs. I am going into hospital next Friday 26th for surgery under an GA and have to take my last apixaban Tuesday evening. Pre op said it was unlikely surgery would go ahead if I was in Afib. I’ve been waiting a year for surgery so I obviously
Frances123
in
Atrial Fibrillation Support
3 months ago
The Life and Times of a Wild Chipmunk
Hi. I have major depression. I am 62, old and broken. Living with beloved cat, Turk in a ratty rented room. Accepted into nursing school only to get cancer at end of 2nd semester. Went to another school and it closed. Stayed with aunt through cardiac surgery and rehab. Lost house and 3/4 of contents,
Hi. I have major depression. I am 62, old and broken. Living with beloved cat, Turk in a ratty rented room. Accepted into nursing school only to get cancer at end of 2nd semester. Went to another school and it closed. Stayed with aunt through cardiac surgery and rehab. Lost house and 3/4 of contents,
Wildchipmunk
in
Anxiety and Depression Support
8 months ago
Amiltryptiline affecting Sertraline
Hi allHas anyone had similar experience to this? I have suffered from depression for most of my adult life and anxiety my latest medication from a long line is sertraline 125 mg to help manage it. I've recently increased amiltryptiline to 40mg at night to help flare up of pain (it was 20 mg). I've been
Hi allHas anyone had similar experience to this? I have suffered from depression for most of my adult life and anxiety my latest medication from a long line is sertraline 125 mg to help manage it. I've recently increased amiltryptiline to 40mg at night to help flare up of pain (it was 20 mg). I've been
Seascapes31
in
Fibromyalgia Action UK
8 months ago
When to take PIP flecainide?
Unfortunately my paroxysmal AF has significantly worsened lately and I am awaiting an ablation. In the meantime my consultant has put me back on flecainide 50mg bi daily plus an additional up to 100mg as PIP if AF kicks in. I’m now in AF almost every week for a few hours. Before it starts I frequently
Unfortunately my paroxysmal AF has significantly worsened lately and I am awaiting an ablation. In the meantime my consultant has put me back on flecainide 50mg bi daily plus an additional up to 100mg as PIP if AF kicks in. I’m now in AF almost every week for a few hours. Before it starts I frequently
Daisy2908
in
Atrial Fibrillation Support
3 months ago
Neck and Shoulder Pain
thank you for this great group. I had an asymptomatic afib incident in March which I was given a cardioversion. My afib subsided for a short time and then on a follow up with my EP I was scheduled for and received an ablation (radio frequency) on June 7, still asymptomatic except now for the last month
thank you for this great group. I had an asymptomatic afib incident in March which I was given a cardioversion. My afib subsided for a short time and then on a follow up with my EP I was scheduled for and received an ablation (radio frequency) on June 7, still asymptomatic except now for the last month
bubbakid
in
Atrial Fibrillation Support
3 months ago
yesterday
i just wanted to post somthing positive i felt really accomplished yesterday at work lots of deliverys the teenagers where freaking out and my manager was really stressed but i took control and made sure we got through dinner rush smoothly used reassurance and positive reinforcement while still getting
i just wanted to post somthing positive i felt really accomplished yesterday at work lots of deliverys the teenagers where freaking out and my manager was really stressed but i took control and made sure we got through dinner rush smoothly used reassurance and positive reinforcement while still getting
brendonkellyrox
in
Anxiety and Depression Support
8 months ago
Started peginterferon alpha 2a treatment
Just recently started the above treatment on the 31st January this year but my oldest daughter has just found out shes 9weeks pregnant and i forgot to ask my consultant if it was ok that on my treatment day is it ok to be around her eg as in she comes to my house to visit or is it similar to chemo treatments
Just recently started the above treatment on the 31st January this year but my oldest daughter has just found out shes 9weeks pregnant and i forgot to ask my consultant if it was ok that on my treatment day is it ok to be around her eg as in she comes to my house to visit or is it similar to chemo treatments
Purplechoclover
in
MPN Voice
8 months ago
Having a hard time getting my usual brands
I order my meds online via my doc who promptly sends the script over to my pharmacy and I have home delivery due to my agoraphobia. My pharmacist knows my sensitivities to certain brands and tries to keep me on the ones I have but every now and then I get something I have never had before or I had a
I order my meds online via my doc who promptly sends the script over to my pharmacy and I have home delivery due to my agoraphobia. My pharmacist knows my sensitivities to certain brands and tries to keep me on the ones I have but every now and then I get something I have never had before or I had a
Jefner
in
Thyroid UK
8 months ago
When to call doctor
Hi all. I was diagnosed with afib last July. I had a cardioversion and was prescribed Eliqiuis and propofenone (a heart rhythm regulator). I had no problems until I drank a little too much wine at a wedding . Now, my heart rate is somewhat erratic and can jump to 160 periodically. It has been like
Hi all. I was diagnosed with afib last July. I had a cardioversion and was prescribed Eliqiuis and propofenone (a heart rhythm regulator). I had no problems until I drank a little too much wine at a wedding . Now, my heart rate is somewhat erratic and can jump to 160 periodically. It has been like
Elainemae
in
Atrial Fibrillation Support
3 months ago
First night on Buprenorphine
So today I took 0.2 mg of Buprenorphine, thinking it was better to start low. The effect was incredible. My legs didn't move at all. In fact, the effect was so effective that I even got scared. My body was so relaxed. I got a little anxious that I may not wake up if I felt sleep. I layed there amazed
So today I took 0.2 mg of Buprenorphine, thinking it was better to start low. The effect was incredible. My legs didn't move at all. In fact, the effect was so effective that I even got scared. My body was so relaxed. I got a little anxious that I may not wake up if I felt sleep. I layed there amazed
Anthas
in
Restless Legs Syndrome
3 months ago
Bisoprolol
Hi Just wondering about my dosage of Bisoprol. When I read related posts on here, most people seem to be on a maximum of 5mg. I’m on 12.5 which I take at night. At my most recent appointment with my cardiologist in March, I asked if it could be reduced as I get so tired on an afternoon and I often have
Hi Just wondering about my dosage of Bisoprol. When I read related posts on here, most people seem to be on a maximum of 5mg. I’m on 12.5 which I take at night. At my most recent appointment with my cardiologist in March, I asked if it could be reduced as I get so tired on an afternoon and I often have
Jonhel
in
Atrial Fibrillation Support
3 months ago
When to take Azidem with Paroxysmal AFib?
I’m into 5 days of AFib. Doesn’t feel too bad except when lying on side. Heart rate between 92-120. When I’ve had AFib before it lasts up to a week and goes away on its own. I don’t know why it starts or stops. If by day 7 it is carrying on should I start Adizem? I was prescribed some when I first
I’m into 5 days of AFib. Doesn’t feel too bad except when lying on side. Heart rate between 92-120. When I’ve had AFib before it lasts up to a week and goes away on its own. I don’t know why it starts or stops. If by day 7 it is carrying on should I start Adizem? I was prescribed some when I first
FiveMilesSouth
in
Atrial Fibrillation Support
3 months ago
Now in Persistent Atrial Fibrillation
I was diagnosed with PAF about 23 years ago, and have managed it with medication, at present on 300mg of Flecainide daily, along with Bisoprolol 2.5mg and Apixaban 10mg, For the last 6 months I've been in AF for weeks and then a couple of day I'm in rhythm. I don't want an ablation. Would I receive
I was diagnosed with PAF about 23 years ago, and have managed it with medication, at present on 300mg of Flecainide daily, along with Bisoprolol 2.5mg and Apixaban 10mg, For the last 6 months I've been in AF for weeks and then a couple of day I'm in rhythm. I don't want an ablation. Would I receive
Bee-Honest
in
Atrial Fibrillation Support
3 months ago
I finally got my sublingual buprenorhine!
Hi everybody! Thanks to this forum I finally got a neurologist who was willing to prescribe me 0.2mg sublingual buprenorphine tablets. I've been on 100 tramadol for two weeks and was wondering which would be the wiser way of switching from one to the other and finding the right dose. I'm a bit worried
Hi everybody! Thanks to this forum I finally got a neurologist who was willing to prescribe me 0.2mg sublingual buprenorphine tablets. I've been on 100 tramadol for two weeks and was wondering which would be the wiser way of switching from one to the other and finding the right dose. I'm a bit worried
Anthas
in
Restless Legs Syndrome
3 months ago
Update on failing Enzalutamide
Hello again friends, I wrote recently after learning that Xtandi was no longer working, seeking options. Since then I have had a consultation with my Oncologist and we went through the (limited) range of options for someone who is living in the UK and being treated on the National Health Service. Brief
Hello again friends, I wrote recently after learning that Xtandi was no longer working, seeking options. Since then I have had a consultation with my Oncologist and we went through the (limited) range of options for someone who is living in the UK and being treated on the National Health Service. Brief
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
Stopping an Afib?
I'm very interested to hear of any methods that you've found that actually stops your Afib and restores NSR.Mine always last 15-24 hours and always returns to NSR while I'm asleep. Flecainide has never improved this scenario and my EP has advised me to stop taking it. I've read peoples stories on here
I'm very interested to hear of any methods that you've found that actually stops your Afib and restores NSR.Mine always last 15-24 hours and always returns to NSR while I'm asleep. Flecainide has never improved this scenario and my EP has advised me to stop taking it. I've read peoples stories on here
Orbitpluto
in
Atrial Fibrillation Support
3 months ago
Ruxolitinib
Hi all, I have PV and AB is high , around 81% , spleen size slightly increased but if I didn’t know I have PV I would think I am the healthiest person around as I have no symptoms. I was diagnosed end of 2018 but had it al least since 2015. I am considering taking a part in clinical trial for Ruxo and
Hi all, I have PV and AB is high , around 81% , spleen size slightly increased but if I didn’t know I have PV I would think I am the healthiest person around as I have no symptoms. I was diagnosed end of 2018 but had it al least since 2015. I am considering taking a part in clinical trial for Ruxo and
Ameliav
in
MPN Voice
1 year ago
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