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Reminder: The virtual LiveLung SCLC group meeting is TONIGHT, June 20th at 7 pm ET.
In addition to his
clinical
practice and participation in immunotherapy-based
clinical
trials
, Dr. Borghaei is the principal investigator (PI) of a laboratory that develops new monoclonal antibodies and novel immune-modulating drugs, with the aim of bringing these approaches to the clinic. Dr.
In addition to his
clinical
practice and participation in immunotherapy-based
clinical
trials
, Dr. Borghaei is the principal investigator (PI) of a laboratory that develops new monoclonal antibodies and novel immune-modulating drugs, with the aim of bringing these approaches to the clinic. Dr.
AmyKamp
Partner
in
Small Cell Lung Cancer Support
1 year ago
Largest real world study of acalabrutinib and ibrutinib over 3 years, shows acalabrutinib has improved discontinuation rates
I omitted to mention that there is also independently confirmed evidence that ibrutinib can improve T cell function - I haven't seen this property mentioned for any of the other ~14 competing BTKi drugs approved or in
clinical
trials
for the treatment of CLL. https://healthunlocked.com/cllsupport/posts
I omitted to mention that there is also independently confirmed evidence that ibrutinib can improve T cell function - I haven't seen this property mentioned for any of the other ~14 competing BTKi drugs approved or in
clinical
trials
for the treatment of CLL. https://healthunlocked.com/cllsupport/posts
AussieNeil
Partner
in
CLL Support
1 year ago
SGLT-2 Inhibitors to (partially) “Starve” Glucose Dependent Cancers
MateoBeach / Paul Effects of novel SGLT2 inhibitors on cancer incidence in hyperglycemic patients: a meta-analysis of randomized
clinical
trials
https://www.sciencedirect.com/science/article/abs/pii/S104366182100623X The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer
MateoBeach / Paul Effects of novel SGLT2 inhibitors on cancer incidence in hyperglycemic patients: a meta-analysis of randomized
clinical
trials
https://www.sciencedirect.com/science/article/abs/pii/S104366182100623X The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer
MateoBeach
in
Fight Prostate Cancer
1 year ago
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Multi-Drug Combo May Be Best Against Prostate Cancer...I thought it was a known fact already!
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
7 months ago
Does it indicate failure of another clinical trial
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Farooqji
in
Cure Parkinson's
7 months ago
A guide to Fall vaccine options - USA by Your Local Epidemiologist
In
clinical
trials
, it reduced the risk of hospitalization and healthcare visits by ~80%. Who: All infants under 8 months should get it for their first RSV season. High-risk children between 8 months to 19 months should also get it.
In
clinical
trials
, it reduced the risk of hospitalization and healthcare visits by ~80%. Who: All infants under 8 months should get it for their first RSV season. High-risk children between 8 months to 19 months should also get it.
lankisterguy
Volunteer
in
CLL Support
1 year ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
7 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
7 months ago
Current SUPERNOVA Clinical Trial for Reformulated EVUSHELD for preventing COVID-19 infection for immune-impaired individuals
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
Classicaljazz
in
CLL Support
7 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
7 months ago
Creatine For Advanced Prostate Cancer Patients
Here's the link: https://www.onclive.com/view/new-
clinical
-
trials
-test-innovative-ways-to-preserve-muscle-mass-during-metastatic-prostate-cancer?
Here's the link: https://www.onclive.com/view/new-
clinical
-
trials
-test-innovative-ways-to-preserve-muscle-mass-during-metastatic-prostate-cancer?
CocoTheAlphaCat
in
Advanced Prostate Cancer
10 months ago
Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
7 months ago
Acalabrutinib and Skin Cancers
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
I began taking Acalabrutinib three years ago as a participant in a clinical trial. I have enjoyed excellent success. However, recently I began breaking out in skin cancer lesions on various parts of the body. Particularly on my legs, ankles and feet. I have been prone to sun damaged skin converting
spanish36
in
CLL Support
7 months ago
Celebrating International Clinical Trials Day.
Tomorrow (19th May) There is an event taking place in the atrium of the QE Hospital, Birmingham Celebrating International
Clinical
Trials
Day. I shall be there talking about people becoming involved in Clinical Research as a PPIE members (Patient and Public Involvement and Engagement).
Tomorrow (19th May) There is an event taking place in the atrium of the QE Hospital, Birmingham Celebrating International
Clinical
Trials
Day. I shall be there talking about people becoming involved in Clinical Research as a PPIE members (Patient and Public Involvement and Engagement).
Richard-Allen
in
British Liver Trust
1 year ago
New technique modifies T-Cells to cure cancer
When examining the results of phase I and II
clinical
trials
, in which 31 patients with malignant melanoma received TIL therapy, researchers found those who successfully cleared their cancer still showed strong T-cell responses over a year later.
When examining the results of phase I and II
clinical
trials
, in which 31 patients with malignant melanoma received TIL therapy, researchers found those who successfully cleared their cancer still showed strong T-cell responses over a year later.
Derf4223
in
Advanced Prostate Cancer
1 year ago
Amitriptyline - ATLANTIS clinical trial
Can anyone explain to me why money has been spent on a clinical trial for amitriptyline in relation to IBS, when this has been prescribed for IBS and specifically IBS pain for years already?: https://www.theibsnetwork.org/blog/irritable-bowel-syndrome-relieved-by-low-dose-amitriptyline/ When investigating
Can anyone explain to me why money has been spent on a clinical trial for amitriptyline in relation to IBS, when this has been prescribed for IBS and specifically IBS pain for years already?: https://www.theibsnetwork.org/blog/irritable-bowel-syndrome-relieved-by-low-dose-amitriptyline/ When investigating
xjrs
in
IBS Network
7 months ago
Thalassemia: Lessons in Perseverance and Compassion
I have participated in countless
clinical
trials
, as well, in gratitude to patients who made my treatment possible, and in honor of the next generation with thalassemia.
I have participated in countless
clinical
trials
, as well, in gratitude to patients who made my treatment possible, and in honor of the next generation with thalassemia.
AnnaHU
HealthUnlocked
in
HealthUnlocked Blog
10 months ago
Senolytics - “senolytic” drugs, dasatinib (D) and quercetin (Q) disapointing results in small test- Peter Attia
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
January 13, 2024 COGNITIVE HEALTH & NEURODEGENERATIVE DISEASE Targeting senescent cells for cognitive health With the recent publication of the first clinical trial of senolytics for AD treatment, popular interest in these drugs has swelled, but is the excitement justified? PETER ATTIA
Scout4answers
in
Fight Prostate Cancer
7 months ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
7 months ago
New Malecare AI Assisted PCa Search
For users of the $20 per month ChatGPT account Malecare is the world's first patient advocacy organization to develop and publish GPT's in Open AI's Chat GPT (app) Marketplace! Indeed, we have five apps published! Here they are: Clinical Trial Navigator -- https://chat.openai.com/g/g-rl6cvjdon-clinical-trial-navigator
For users of the $20 per month ChatGPT account Malecare is the world's first patient advocacy organization to develop and publish GPT's in Open AI's Chat GPT (app) Marketplace! Indeed, we have five apps published! Here they are: Clinical Trial Navigator -- https://chat.openai.com/g/g-rl6cvjdon-clinical-trial-navigator
dmt1121
in
Advanced Prostate Cancer
7 months ago
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