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Carbidopa / Levodopa
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Check Out the Stack on This Guy!
Balancing the Apoptotic Switch – From Cancer to Parkinson’s Disease - 2016 https://www.jscimedcentral.com/DrugDesign/drugdesign-4-1030.pdf I Got Duped by a fake journal!! Thanks Hikoi! http://flakyj.blogspot.com/2017/01/jscimed-central-jsm.html JSciMed Central aims to harbor the journal free from the
Balancing the Apoptotic Switch – From Cancer to Parkinson’s Disease - 2016 https://www.jscimedcentral.com/DrugDesign/drugdesign-4-1030.pdf I Got Duped by a fake journal!! Thanks Hikoi! http://flakyj.blogspot.com/2017/01/jscimed-central-jsm.html JSciMed Central aims to harbor the journal free from the
Bolt_Upright
in
Cure Parkinson's
3 years ago
More Bee Stuff: Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster - 2020
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-parkinsonism-indrosophila-.pdf?sequence=1&isAllowed=y The study showed that the administration of ethanolic extract of propolis (500 mg/mL) with levodopa (250 mg/kg) not only significantly
http://idr.kab.ac.ug/bitstream/handle/20.500.12493/439/synergistic-action-of-propolis-with-levodopa-in-the-management-of-parkinsonism-indrosophila-.pdf?sequence=1&isAllowed=y The study showed that the administration of ethanolic extract of propolis (500 mg/mL) with levodopa (250 mg/kg) not only significantly
Bolt_Upright
in
Cure Parkinson's
3 years ago
Vinpocetine regulates levels of circulating TLRs in Parkinson's disease patients 2019
I started today asking "what can I remove from my stack?" And of course, now I am probably adding to my stack: https://www.researchgate.net/publication/328251573_Vinpocetine_regulates_levels_of_circulating_TLRs_in_Parkinson%27s_disease_patients As close as I can tell, it looks like the dosing was 20
I started today asking "what can I remove from my stack?" And of course, now I am probably adding to my stack: https://www.researchgate.net/publication/328251573_Vinpocetine_regulates_levels_of_circulating_TLRs_in_Parkinson%27s_disease_patients As close as I can tell, it looks like the dosing was 20
Bolt_Upright
in
Cure Parkinson's
3 years ago
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Citicoline as Adjuvant Therapy in Parkinson's Disease: A Systematic Review 2017
Findings A total of 7 studies (2 crossover, 3 randomized controlled, and 2 open prospective studies) were included. Despite the varied outcome tools, this review found that patients with PD who were taking citicoline had significant improvement in rigidity, akinesia, tremor, handwriting, and speech.
Findings A total of 7 studies (2 crossover, 3 randomized controlled, and 2 open prospective studies) were included. Despite the varied outcome tools, this review found that patients with PD who were taking citicoline had significant improvement in rigidity, akinesia, tremor, handwriting, and speech.
Bolt_Upright
in
Cure Parkinson's
3 years ago
Surprise, surprise. "When should you start medication therapy for Parkinson's disease?" as per THE PARKINSON'S FOUNDATION.
"The most important factor in initiating medications for an individual patient is whether Parkinson’s symptoms are affecting quality of life, (read; interfering with...) or alternatively whether symptoms are affecting work performance." Read; not automatically at the time of diagnosis. https://www.parkinson.org
"The most important factor in initiating medications for an individual patient is whether Parkinson’s symptoms are affecting quality of life, (read; interfering with...) or alternatively whether symptoms are affecting work performance." Read; not automatically at the time of diagnosis. https://www.parkinson.org
MBAnderson
in
Cure Parkinson's
3 years ago
How Mucuna Pruriens can help body builders !
https://www.healthessentialsdirect.co.uk/blogs/news/mucuna-pruriens-muscle-building
https://www.healthessentialsdirect.co.uk/blogs/news/mucuna-pruriens-muscle-building
Thal
in
Cure Parkinson's
3 years ago
Why Does High Dose Thiamine Work?
I like to keep challenging the items in my stack. HDT is in my stack. I believe in HDT. But why? So far I trust HDT because of the results from Dr Constantini and the testimonials. Time to look for some science: Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children
I like to keep challenging the items in my stack. HDT is in my stack. I believe in HDT. But why? So far I trust HDT because of the results from Dr Constantini and the testimonials. Time to look for some science: Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children
Bolt_Upright
in
Cure Parkinson's
3 years ago
Where to from here?
Writing to you from New Zealand where thus far we have had no contact with other PSP sufferers. In late 2019 my wife (80yrs) had significant weight loss and tremor. Was originally diagnosed with BET (Benign Essential Tremor). Some months later this was changed to Parkinson's. Prescribed levodopa with
Writing to you from New Zealand where thus far we have had no contact with other PSP sufferers. In late 2019 my wife (80yrs) had significant weight loss and tremor. Was originally diagnosed with BET (Benign Essential Tremor). Some months later this was changed to Parkinson's. Prescribed levodopa with
BlairWit
in
PSP Association
3 years ago
Associations between osteoporosis and drug exposure: a post-marketing study of the World Health Organization pharmacovigilance database
This is a comprehensive paper on the impact of medicines on bone density, osteoporosis and fracture. Thyroid hormones are listed but their impact appears considerably lower than for Proton Pump Inhibitors (PPIs), Methotrexate, Steroids, Hydroxychloroquine, and others. It is also often mentioned here
This is a comprehensive paper on the impact of medicines on bone density, osteoporosis and fracture. Thyroid hormones are listed but their impact appears considerably lower than for Proton Pump Inhibitors (PPIs), Methotrexate, Steroids, Hydroxychloroquine, and others. It is also often mentioned here
helvella
Thyroid UK
in
Thyroid UK
3 years ago
Grapefruit reduced carbidopa-levodopa?
Those of you that have had or are having experience with grapefruit juice, how is it going?
Those of you that have had or are having experience with grapefruit juice, how is it going?
Hidden
in
Cure Parkinson's
3 years ago
Sinemet v carbo levodopa g
Sinemet is the Origina make/brand for levodopa and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me. They don’t work well at
Sinemet is the Origina make/brand for levodopa and I have always had this made by Merrick Sharp Dohme Recently in found to my cost that it longer under special licence and it can be made by anyone now, but I was unaware that they would have such a different effect on me. They don’t work well at
Connie18
in
Cure Parkinson's
3 years ago
Ropinerole and Muncuna Pruriens
Has anyone had any experience of combining Ropinerole with high strength Mucuna Pruriens L-Dopa extract capsules food supplement? I am on 0.5mg of Ropinerole and reluctant to increase the dosage due to augmentation so I have just started to take Muncuna early in the evening followed by Ropinerole before
Has anyone had any experience of combining Ropinerole with high strength Mucuna Pruriens L-Dopa extract capsules food supplement? I am on 0.5mg of Ropinerole and reluctant to increase the dosage due to augmentation so I have just started to take Muncuna early in the evening followed by Ropinerole before
dahon
in
Restless Legs Syndrome
3 years ago
REFINING MY PREVIOUS QUESTION (,,, food for thought): should it be preferable in PSP to take phenylalanine instead of tyrosin supplements?
REFINING MY QUESTION (,,, food for thought...) Tyrosine is a dopamine percursor and as such appears to be a good option for supplementation in PSP. “Tyrosine hydroxylase” is the enzyme responsible for catalyzing the conversion of the amino acid L- tyrosine to L-DOPA. Tyrosine can also be made of phenylalanine
REFINING MY QUESTION (,,, food for thought...) Tyrosine is a dopamine percursor and as such appears to be a good option for supplementation in PSP. “Tyrosine hydroxylase” is the enzyme responsible for catalyzing the conversion of the amino acid L- tyrosine to L-DOPA. Tyrosine can also be made of phenylalanine
BluesHealer
in
PSP Association
3 years ago
Mannitol and B1: What’s going on?
Last September, my hwp for 16 years, started mannitol. Over the next months, this gradually allowed him to reduce his dopamine meds, first eliminating the Neupro patch, then gradually eliminating Rytary. He has cognitive impairment and too much of those 2 meds would cause hallucinations. But dialing
Last September, my hwp for 16 years, started mannitol. Over the next months, this gradually allowed him to reduce his dopamine meds, first eliminating the Neupro patch, then gradually eliminating Rytary. He has cognitive impairment and too much of those 2 meds would cause hallucinations. But dialing
LeharLover62
in
Cure Parkinson's
3 years ago
Back to Melatonin - Dosing?
I won't go as deep as Art does on Melatonin, but am picking up on a point Art makes often: Dosing! I read all these papers and frankly skim over a lot. Today somebody on FB reposted one of my favorites: 2021 - Melatonin as a Chronobiotic and Cytoprotective Agent in Parkinson’s Disease https://www.ncbi.nlm.nih.gov
I won't go as deep as Art does on Melatonin, but am picking up on a point Art makes often: Dosing! I read all these papers and frankly skim over a lot. Today somebody on FB reposted one of my favorites: 2021 - Melatonin as a Chronobiotic and Cytoprotective Agent in Parkinson’s Disease https://www.ncbi.nlm.nih.gov
Bolt_Upright
in
Cure Parkinson's
3 years ago
ARE YOU A NON TREMOR DOMINANT PD PATIENT WITH DYSKINESIA? IF SO, PLEASE HELP.
Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
Hi, your suggestions would help a lot. I am beginning to have dyskinesia more frequently. Mostly worse at night. I take Rytary 3pills 145mg, (8am,12noon,4pm and 8pm). My MDS thinks it is motor fluctuations, caused by uneven plasma level of Levodopa. He suggested that I should add two more pills,
OREOLU
in
Cure Parkinson's
3 years ago
Scheduling meals around taking Carbidopa/Levodopa medication
I have found it challenging to schedule taking my medication: one hour before a meal and two hours after a meal. Recently with my Doctor's approval, I increased my Carbopa/Levodopa 25 dosage from 3 times a day to 4 times a day. The increase has made a difference. I still have difficulty scheduling
I have found it challenging to schedule taking my medication: one hour before a meal and two hours after a meal. Recently with my Doctor's approval, I increased my Carbopa/Levodopa 25 dosage from 3 times a day to 4 times a day. The increase has made a difference. I still have difficulty scheduling
kathydubro
in
Cure Parkinson's
3 years ago
A potential case of remission of Parkinson’s disease
Karishma Smart*, Raymon Durso, Jonathan Morgan and Patrick McNamaraA potential case of remissionof Parkinson’s diseaseDOI 10.1515/jcim-2016 https://mindandculture.org/wordpress6/wp-content/uploads/2018/05/SmartDursoMorganMcNamara-A-Potential-Case-of-Remission-of-Parkinsons-Disease.pdf The patient meditates
Karishma Smart*, Raymon Durso, Jonathan Morgan and Patrick McNamaraA potential case of remissionof Parkinson’s diseaseDOI 10.1515/jcim-2016 https://mindandculture.org/wordpress6/wp-content/uploads/2018/05/SmartDursoMorganMcNamara-A-Potential-Case-of-Remission-of-Parkinsons-Disease.pdf The patient meditates
Bolt_Upright
in
Cure Parkinson's
3 years ago
We need to move more quickly to focused ultrasound (FUS)
About half a century ago, the merrRAdical profession established
carbidopa
/
levodopa
as the standard treatment for Parkinson’s disease; and it has been so ever since. But replacing dopamine is not a cure, does not always work, and can lose effectiveness over time.
About half a century ago, the merrRAdical profession established
carbidopa
/
levodopa
as the standard treatment for Parkinson’s disease; and it has been so ever since. But replacing dopamine is not a cure, does not always work, and can lose effectiveness over time.
jack-edmonston
in
Cure Parkinson's
3 years ago
example: High Dose Levodopa and Sleep
Restated, this should be the
Carbidopa
/
Levodopa
dose identified as optimal; the sleep benefit requires a full dose. Another dose may be taken upon awakening in the middle of the night, if necessary to sustain sleep.” Full optimal dose, two 100 mg tablets for a total of 200 mg.
Restated, this should be the
Carbidopa
/
Levodopa
dose identified as optimal; the sleep benefit requires a full dose. Another dose may be taken upon awakening in the middle of the night, if necessary to sustain sleep.” Full optimal dose, two 100 mg tablets for a total of 200 mg.
Hidden
in
Cure Parkinson's
3 years ago
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