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Only ADT first or add second generation ADT too at start ?
Dad is going to start ADT shortly. He has bone mets One MO said to start with Zoladex and after two weeks to add xtandi ( starting 40 mg ) The other MO says to start only Zoladex and will think of xtandi or zytiga later at some point , maybe when Zoladex starts being less effective. He says if
Dad is going to start ADT shortly. He has bone mets One MO said to start with Zoladex and after two weeks to add xtandi ( starting 40 mg ) The other MO says to start only Zoladex and will think of xtandi or zytiga later at some point , maybe when Zoladex starts being less effective. He says if
Tinkudi
in
Advanced Prostate Cancer
21 days ago
What's on at Ovacome next week? (week commencing Monday 10 June 2024)
Good afternoon everyone, This is our weekly post to let you know about the different support groups, workshops and events taking place at Ovacome next week. Monday 10 June -Monday monthly meet-up between 4:00pm - 5:30pm: https://www.ovacome.org.uk/Event/monday-monthly-meet-up Tuesday 11 June
Good afternoon everyone, This is our weekly post to let you know about the different support groups, workshops and events taking place at Ovacome next week. Monday 10 June -Monday monthly meet-up between 4:00pm - 5:30pm: https://www.ovacome.org.uk/Event/monday-monthly-meet-up Tuesday 11 June
OvacomeSupport
My Ovacome Team
in
My Ovacome
21 days ago
What are the better treatments for metastasis of the bone and pelvic lymph nodes?
Just found out the past few weeks from a biopsy and a PET/CT scan that the cancer was not contained in the prostate but metastasized to the pelvic lymph nodes and the bones. Was a surprise to me and to the urologist as well. He is recommending no surgery but a multimodal therapy with androgen deprivation
Just found out the past few weeks from a biopsy and a PET/CT scan that the cancer was not contained in the prostate but metastasized to the pelvic lymph nodes and the bones. Was a surprise to me and to the urologist as well. He is recommending no surgery but a multimodal therapy with androgen deprivation
PARKER3237
in
Advanced Prostate Cancer
21 days ago
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Kishan's 6 month Androgen Annihilation Therapy Study for metastatic PCa
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
https://x.com/prostatecell/status/1770206641813696808?s=46 https://bit.ly/43rr68x seems to be a promising tactic for oligometastatic PCa, that combines SBRT with an ADT mix . The Abstract starts off by noting that with metastatic hormone sensitive PCa, recurrence almost always happens within six months
Xavier10
in
Advanced Prostate Cancer
21 days ago
83 years old - Firmagon or Zoladex ? Conflicted which to choose.
Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issues but we have a strong family history of cardiac disease. His dad and brother both passed from it He also gets ectopic beats/ pvc’s since many years but all cardiologists say those are benign and not to bother. His blood
Dad is 83 and has to start on ADT from Tomorrow. He has no known cardiac issues but we have a strong family history of cardiac disease. His dad and brother both passed from it He also gets ectopic beats/ pvc’s since many years but all cardiologists say those are benign and not to bother. His blood
Tinkudi
in
Advanced Prostate Cancer
21 days ago
Phase 1/2 ARV-766 clinical trial
“The purpose of this study is to assess the safety and tolerability (good and bad effects) and how prostate cancer responds to two different doses of the investigational study drug (ARV-766) in combination with Abiraterone in men with metastatic cRPC who have not received prior novel hormonal therapies
“The purpose of this study is to assess the safety and tolerability (good and bad effects) and how prostate cancer responds to two different doses of the investigational study drug (ARV-766) in combination with Abiraterone in men with metastatic cRPC who have not received prior novel hormonal therapies
Woodman33
in
Advanced Prostate Cancer
21 days ago
Why would a doctor ask for an MRI both with and without contrast to see if I have just a fibroid or if there is an ovarian mass as well?
I had both a CT and ultrasound and they couldn't be 100% sure if I had a mass on my ovary or if it is a pedunculated fibroid. My doctor wrote to the OB/GYN and her response was this: [i]I would recommend a pelvic MRI with and without contrast. It tends to be much better at delineating pelvic structures
I had both a CT and ultrasound and they couldn't be 100% sure if I had a mass on my ovary or if it is a pedunculated fibroid. My doctor wrote to the OB/GYN and her response was this: [i]I would recommend a pelvic MRI with and without contrast. It tends to be much better at delineating pelvic structures
starrynight5626
in
My Ovacome
21 days ago
Bra after lung surgery?
What bras did you find most comfortable post surgery or maybe I should be asking, what bras did you find most tolerable? (Not initially after but a few weeks after surgery). Thanks in advance for your responses. I'm asking on behalf of someone else. Also, we are currently working to create a lung cancer
What bras did you find most comfortable post surgery or maybe I should be asking, what bras did you find most tolerable? (Not initially after but a few weeks after surgery). Thanks in advance for your responses. I'm asking on behalf of someone else. Also, we are currently working to create a lung cancer
Miranda_GO2
Partner
in
Lung Cancer Support
22 days ago
PSA Still Going Up
I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went up to 0.015 ng/mL in January 2024 and went up to 0.035 ng/mL in my current test. I know Tall Allen said the previous number was negligible because
I had RP on January 2023, started ADT in May 2023 and went through 38 sessions of radiation. In November 2023, my PSA went down to 0.005 ng/mL. My PSA went up to 0.015 ng/mL in January 2024 and went up to 0.035 ng/mL in my current test. I know Tall Allen said the previous number was negligible because
toyman79912
in
Advanced Prostate Cancer
22 days ago
Interested in joining GO2's Mind Over Matter group?
What is Mind Over Matter (also known as MOM)?
In this group, you will learn tips and tools to handle the big feelings that often come up after a cancer diagnosis and treatment. This 5-week group can help you deal with the fears, worries, and sadness that come up for many people.
Who can join
What is Mind Over Matter (also known as MOM)?
In this group, you will learn tips and tools to handle the big feelings that often come up after a cancer diagnosis and treatment. This 5-week group can help you deal with the fears, worries, and sadness that come up for many people.
Who can join
Miranda_GO2
Partner
in
Lung Cancer Support
22 days ago
FDA Greenlights Phase 2/3 Trial of KPG-121/Abiraterone in mCRPC
A clinical trial to evaluate the combination of a new drug called KPG-121 with abiraterone acetate (Zytiga) for treating metastatic castration-resistant prostate cancer (mCRPC) as a first-line therapy has been approved by the FDA. KPG-121 is an investigational drug that targets specific proteins involved
A clinical trial to evaluate the combination of a new drug called KPG-121 with abiraterone acetate (Zytiga) for treating metastatic castration-resistant prostate cancer (mCRPC) as a first-line therapy has been approved by the FDA. KPG-121 is an investigational drug that targets specific proteins involved
God_Loves_Me
in
Advanced Prostate Cancer
22 days ago
Voice weak after thyroidectomy
I had a thyroidectomy 5 years ago and after surgery had a check on vocal cords which were fine. However my voice has recently become a bit weaker and I constantly have to cough to clear my throat. Is this normal so long after surgery?
I had a thyroidectomy 5 years ago and after surgery had a check on vocal cords which were fine. However my voice has recently become a bit weaker and I constantly have to cough to clear my throat. Is this normal so long after surgery?
red_devil22
in
Thyroid UK
22 days ago
PSA 8 months after EBRT
I need some reassurance. I tend to worry a little bit so please let me know if the following is or could be somewhat normal. As per my history, I had 4+3 per Dr. Epstein, had Pylarify with no mets, seed implant LD brachytherapy in July 2023, EBRT 28 treatments finishing first of Oct 2023. RO said ADT
I need some reassurance. I tend to worry a little bit so please let me know if the following is or could be somewhat normal. As per my history, I had 4+3 per Dr. Epstein, had Pylarify with no mets, seed implant LD brachytherapy in July 2023, EBRT 28 treatments finishing first of Oct 2023. RO said ADT
electronics-guy
in
Prostate Cancer Network
22 days ago
Falling ALT - Pathway to Sarcopenia? - More Exercise Needed?
Two years in to my de novo high volume metastatic prostate cancer diagnosis, I am pleased to report excellent results so far with triplet therapy (Docetaxel chemo completed, Abiraterone ARPI, Firmagon/Degarelix GnRH antagonist as ADT). However I would be grateful for any advice today.
My ALT has fallen
Two years in to my de novo high volume metastatic prostate cancer diagnosis, I am pleased to report excellent results so far with triplet therapy (Docetaxel chemo completed, Abiraterone ARPI, Firmagon/Degarelix GnRH antagonist as ADT). However I would be grateful for any advice today.
My ALT has fallen
JohnInTheMiddle
in
Advanced Prostate Cancer
22 days ago
Has Anyone Any Knowledge Concerning The Oregano Chief Compound, "Carvacrol" And Its Ability To Fight PCa?
There are tons of reports and articles on the internet that state that the chief
Oregano
herb compound [i]
Carvacrol
[/i] outright "kills prostate cancer cells." Reports on studies about Carvacrol's prostate cancer cell-destroying ability seemed to have first began emerging around
There are tons of reports and articles on the internet that state that the chief
Oregano
herb compound [i]
Carvacrol
[/i] outright "kills prostate cancer cells." Reports on studies about Carvacrol's prostate cancer cell-destroying ability seemed to have first began emerging around
back2health
in
Advanced Prostate Cancer
22 days ago
JUN protein could slow prostate cancer growth, study finds
"The results, which have just been published in the top journal "Molecular Cancer", provide a new starting point for the development of therapies..... Our research suggests that activating JUN could potentially be a promising therapeutic option for slowing the progression of prostate cancer" https
"The results, which have just been published in the top journal "Molecular Cancer", provide a new starting point for the development of therapies..... Our research suggests that activating JUN could potentially be a promising therapeutic option for slowing the progression of prostate cancer" https
SimonHL
in
Advanced Prostate Cancer
22 days ago
Could This Alternative Regiment Be Decelerating My PSA?
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
Between Summer of 2021 and Summer of 2023--two solid years--my PSA went from 11.5 to 15.3, roughly two points per year. Having concern about my PSA, I ventured into a more "aggressive anti-prostate cancer diet," centered around legumes/black, purple, wild rices/walnuts/flaxseed/tomato paste
back2health
in
Advanced Prostate Cancer
22 days ago
Casodex - stop or continue ?
Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist started him on Casodex 100 mg to take daily and then take a lupron shot after 2-3 weeks. Before starting the Casodex he had bone pain in a femur and was taking Ibuprofen sometimes but since starting the Casodex since the
Dad , 83 , got diagnosed last month with bone mets and psa 18. The urologist started him on Casodex 100 mg to take daily and then take a lupron shot after 2-3 weeks. Before starting the Casodex he had bone pain in a femur and was taking Ibuprofen sometimes but since starting the Casodex since the
Tinkudi
in
Advanced Prostate Cancer
22 days ago
Need info on blood in urine
Diagnosed with prostate cancer 4 1/2 years ago. Had prostate removed Sept. 2019 and had radiation winter 2020/2021 because PSA was going higher. Radiation is causing blood in my urine periodically. Now that I am older the blood in my urine seems to occur more often. I read on the internet that if
Diagnosed with prostate cancer 4 1/2 years ago. Had prostate removed Sept. 2019 and had radiation winter 2020/2021 because PSA was going higher. Radiation is causing blood in my urine periodically. Now that I am older the blood in my urine seems to occur more often. I read on the internet that if
peanutbutter2
in
Prostate Cancer Network
22 days ago
Best alternative PET for PSMA negative PCa
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Asking for a friend. He was diagnosed 3 years ago with high risk high volume (Gleason 3+5) PCa. Treated with EBRT + LDRBT + ADT (18 months). His PSA was undetectable but is now rising (3+) but PSMA-PET was negative, even in the prostate - implying PSMA non-avid cancer. What would be the best non-PSMA
Vynbal
in
Advanced Prostate Cancer
23 days ago
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