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new immune therapy phase 1-2 trial: targeting NK cells
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
The first patient with metastatic castration-resistant prostate cancer (mCRPC) has been dosed in the phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
https://www.targetedonc.com/view/first-patient-dosed-with-inkmune-therapy-in-phase-1-2-trial-for-mcrpc
Maxone73
in
Advanced Prostate Cancer
5 months ago
InkMune clinical trial goes on: second cohort is being treated
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial.
In phase 1/2 CaRe PC trial (NCT06056791) evaluating INKmune, a
biologic
therapy
In its announcement on Monday, INmune said it successfully completed nine INKmune administrations in the outpatient setting within the first cohort in the trial.
Maxone73
in
Advanced Prostate Cancer
5 days ago
biologic therapy blood tests to start Adalimumab
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Hi after azaoprine caused liver cirrhosis, my consultant said I should start Adalimumab . I have had lots of various bloods taken including TB, HIV. Is this normal? 😳
Bucket13
in
Crohn's and Colitis Support
1 year ago
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Change in inhalers
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
I'm currently on sertide and being switched over to symbicort. I'm not sure of the dosage etc as need to discuss further with gp. I'm a little concerned as been on seretide for years. When I get switched it triggers flares and I've already had loads of time of work. I work part time. I also think I'm
spookylou
in
Asthma Community Forum
1 month ago
No meds no symptoms
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
I was told a week ago to stop all my medication due to a chest infection and WBC being too low. I've been off my hydroxychloroquine and methotrexate for over a week now and weirdly my joints and swelling has been the best it's been for over 2 years. I feel perplexed has a 2 year flare just finished
Sunshine634
in
LUPUS UK
1 month ago
Biological therapy.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
I have been reading through all the posts on biological therapy.I have literally this week just heard that I qualify for Tezspire. The wait time is about 4 weeks. I am wondering who else is having this / had it and how they are getting on . Thank you.
pmrdec112014
in
Asthma Community Forum
1 month ago
biologic therapy
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
I have been on methotrexate for 20 years for RA. I started at 10 mg. Went to 15mg fairly promptly and then 20mg last year. In general I had no side effects and good quality of life. Recently I started to have a lot of flares and my rheumatologist has recommended a biologic. He said I could try upping
Barrcroom
in
NRAS
1 year ago
Greater use of Benlysta, Saphnelo seen in US, EU to treat lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids — steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects — among people with moderate to severe lupus
Goal to reduce long-term glucocorticoids use to prevent side effects
In both the U.S. and Europe, clinicians want to limit treatment with glucocorticoids — steroid hormones whose long-term use for autoimmune diseases is tied to serious side effects — among people with moderate to severe lupus
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
7 months ago
Biologic therapies
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! 🫣
I am interested to know if anyone found the injection painful? My first was in the thigh and I am wondering if next time to try the arm or stomach area? Or am I just being a big baby?! 🫣
Headoverheels
in
Asthma Community Forum
10 months ago
Side effects on combination therapy : thyroxine and T3
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
I have been on combination therapy for about 7 weeks. I have noticed I am quite breathless and this looks like it can be related but unusual. Does this sound familiar to anyone?
TheaW
in
Thyroid UK
7 hours ago
Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
Source Link : https://www.nature.com/articles/s41388-024-03059-4 Docetaxel (DX) serves as a palliative treatment option for metastatic prostate cancer (PCa). Despite initial remission, acquired DX resistance is inevitable. The mechanisms behind DX resistance have not yet been deciphered, but a mesenchymal
God_Loves_Me
in
Advanced Prostate Cancer
14 hours ago
constipation leading to Pelvic Floor dysfunction
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
I have IBS - C and over the years the medical fraternity have prescribed laxatives for me. I’m following a low fermentation & FODMAP diet which works well for me. However my constipation due to a lot of straining has turned into PFD which basically means my anal muscles are out of sync. Does anyone suffer
Profound15
in
IBS Network
1 day ago
Enemas for constipation
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
I am taking flecainide and bisoprolol for my afib. The medication is doing fine but I’ve got what I believe to be Pelvic Floor dysfunction. Basically one of my rectum muscles (at exit) is contracting when it should be relaxing. I’ve got biofeedback physio on Monday but wanted to know if anyone has experience
Profound15
in
Atrial Fibrillation Support
1 day ago
Interesting new targeted therapy trial
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
I like this company’s mission. They have a Phase 1/2 trial underway at Mass General in Boston with a new miRNA-10b treatment. https://www.transcodetherapeutics.com TransCode’s lead therapeutic candidate, TTX-MC138, is a targeted therapy designed to treat cancer patients with metastatic cancer,
Best521
in
SHARE Metastatic Breast Cancer
3 days ago
Holistic POSITIVE results
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
Hello, I was dx with PD in 2019. I’ve progressed to stage 3 and have tried a lot of synthetic meds. I wont take tgem if the side effects worsen my current symptoms. That excludes most. I have read a million articles on new and upcoming tests and trials. I’m tired of chasing the rabbit. Although I cant
GigiOf8
in
Cure Parkinson's
5 days ago
Obstructed Defaecation Syndrome
Hi everyone, Does any of you have Obstructed Defaecation Syndrome caused by Dyssynergic Defecation? I have been referred to biofeedback therapy that I will start on the 21st of May. I hope it will be helpful for me.
Hi everyone, Does any of you have Obstructed Defaecation Syndrome caused by Dyssynergic Defecation? I have been referred to biofeedback therapy that I will start on the 21st of May. I hope it will be helpful for me.
EnikoF
in
IBS Network
8 days ago
What Kidney Patients Need to Know About Medical Nutrition Therapy
Medical Nutrition Therapy (MNT) is an evidence-based medical approach to treating certain chronic conditions through the use of an individually tailored nutrition plan based on a comprehensive nutrition assessment conducted by a Registered Dietitian (RD). Tell Congress to support the Medical Nutrition
Medical Nutrition Therapy (MNT) is an evidence-based medical approach to treating certain chronic conditions through the use of an individually tailored nutrition plan based on a comprehensive nutrition assessment conducted by a Registered Dietitian (RD). Tell Congress to support the Medical Nutrition
JackieJ_NKF
Partner
in
Kidney Dialysis
9 days ago
Vocal chord damage in thyroidectomy
Hi all, I had a total Thyroidectomy 2 days ago which was a difficult op. My thyroid had grown so large it was pressing on my larynx, growing downwards to my chest, and growing round the back of my oesophagus. In previous surgery for breast cancer 2 years ago they were unable to get the breathing tube
Hi all, I had a total Thyroidectomy 2 days ago which was a difficult op. My thyroid had grown so large it was pressing on my larynx, growing downwards to my chest, and growing round the back of my oesophagus. In previous surgery for breast cancer 2 years ago they were unable to get the breathing tube
Peppermint20
in
Thyroid UK
9 days ago
Gene therapy
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first gene therapy trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-gene-therapy-trial?CMP=share_btn_url
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first gene therapy trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-gene-therapy-trial?CMP=share_btn_url
WinnieThePoo
in
Cure Parkinson's
9 days ago
speech therapist questions
my mum will be visiting a speech therapist tomorrow, what are the areas you suggest the speech therapist should focus on? What questions do you think will be helpful?
my mum will be visiting a speech therapist tomorrow, what are the areas you suggest the speech therapist should focus on? What questions do you think will be helpful?
Candor8
in
PSP Association
10 days ago
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