Melatonin and thyroid: I've read previous posts... - Thyroid UK

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Melatonin and thyroid

redsquirrel68 profile image
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I've read previous posts here about melatonin and would like to enquire more in detail. I suffer bad jet lag when I travel east due to 8 hours time difference. The only thing that has helped me in the past is taking melatonin 5-6mg just before I go to bed. I tend to need it for the first 5-6 days before I can regain normal sleep pattern without any aid.

I have just started taking Liothyronine with my Levo this week. I used to take Levo at 6am but understand from this forum it is better to have 3-4 hours of empty stomach before and after medicating, so I decided to switch to ~3am when I wake up to go to the bathroom. Unfortunately, after 3 days, I find it difficult to go back to sleep and I wake up feeling exhausted.

I'm now thinking of taking my dose at night before sleep as I can easily adjust my meal time accordingly to allow for the 3-4 hours gap. So my question relates to if taking melatonin at night at the same time as my thyroid medication will cause any conflict?

Thank you all again.

Edit: I just remembered since Liothyronine has a short half life and I am only on a starter dose once a day, I should take it in the morning with my Levo.

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redsquirrel68
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Regenallotment profile image
RegenallotmentAmbassador

hey there

I take Levo and Lio together at 6am, get up 6.30 breakfast just after 7.00 I don’t know about the 3-4 hours thing. Sounds a bit over the top to me. The only thing I avoid is magnesium close to Levo as that really affected my absorption. The PIL says 1 hour on my brands. I’d go back to your old routine and add the Lio if it was me. I also tried splitting Lio into 2 doses a day, but that makes me tired in the afternoons.

I’m not familiar with taking melatonin myself, I know some young people who find it helps with ADHD and sleep problems and another with FND and sleep problems/anxiety.

If you had Levo/Lio at 6am could you have melatonin at 10-11pm?

redsquirrel68 profile image
redsquirrel68 in reply toRegenallotment

Thanks.! That's probably what I'll do, melatonin at night and stay with Levo and Lio at 6am.

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