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CLL survival times ARE improving, thanks to BTK and BCL-2 inhibitors
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
Many of us were shocked after our CLL/SLL diagnosis when we googled for survival times. [u]Hopefully[/u] we subsequently read that search engine information from Google, Bing, etc., is way out of date, due to the fact that with CLL being a chronic disease, the relatively long survival times with this
AussieNeil
Partner
in
CLL Support
4 months ago
NCT04662580 - All about ARX517 as Monotherapy
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
God_Loves_Me
in
Advanced Prostate Cancer
4 months ago
Photopharmics kickstarts phototherapy trial for Parkinson’s disease
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
The US Food and Drug Administration (FDA)-approved device targets photoreceptors in the eye responsible for circadian signalling. Research has shown that Parkinson’s disease can damage the retina and impact the circadian system leading to symptoms such as trouble sleeping, cognition, depression, and
Farooqji
in
Cure Parkinson's
4 months ago
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New to Afib- tiredness
Diagnosed a little over a week ago with Afib. On Diltazem and Eloquis. I am 58 years old and always been healthy until now. They have given me Flecainide to start taking daily if I have another episode. My question is about being so tired all the time. I sleep a lot but have to work full time.
Diagnosed a little over a week ago with Afib. On Diltazem and Eloquis. I am 58 years old and always been healthy until now. They have given me Flecainide to start taking daily if I have another episode. My question is about being so tired all the time. I sleep a lot but have to work full time.
Jeep2021
in
AF Association
10 months ago
Anecdotal, but running could boost immunity
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a high
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a high
PeggySusi
Graduate
in
Couch to 5K
4 months ago
Anecdotal, but indicates that exercise boosts immunity
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a
I am reading a lovely book of essays called These Precious Days by Ann Patchett. In the title essay a friend of the author is taking part in a clinical trial, having chemotherapy for pancreatic cancer. As you will know, Chemo destroys white blood cells which provide immunity, so you have to have a
PeggySusi
in
Active 10
4 months ago
low T4 and T3 normal TSH
I posted earlier in the year about my daughter diagnosed with post partum thyroiditis , no treatment at the time but endocrinologist said he’d keep an eye on her! Her most recent results seem odd to me in that both T4 and T3 are very low but her TSH is also low - her case has been closed and results
I posted earlier in the year about my daughter diagnosed with post partum thyroiditis , no treatment at the time but endocrinologist said he’d keep an eye on her! Her most recent results seem odd to me in that both T4 and T3 are very low but her TSH is also low - her case has been closed and results
Sususulio
in
Thyroid UK
10 months ago
Dutasteride reduces PSA by 40% over 6 months
This companion chart from data reported in Moore (2017) compares PSA, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o
This companion chart from data reported in Moore (2017) compares PSA, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o
janebob99
in
Prostate Cancer Network
4 months ago
Dutasteride Reduces Tumor Volume by 30% after 6 months.
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
This chart compares prostate cancer tumor volume measured by MRI, at baseline and at 6 months, comparing placebo to Dutasteride. This was a randomized, double-blind, placebo-controlled clinical trial. The cohort included Low and Intermediate Risk men, GS-6-7, baseline PSA = 6-7, median age 64 y.o,
janebob99
in
Prostate Cancer Network
4 months ago
unanswered questions
I'm excited to be leaving for The International PBC Summit in Edinburgh the end of next week. I'll be bringing back as much information to you as I can about research being done for the cause of PBC, itching and fatigue. All of these issues have impacted all of our lives to some degree. Many of us have
I'm excited to be leaving for The International PBC Summit in Edinburgh the end of next week. I'll be bringing back as much information to you as I can about research being done for the cause of PBC, itching and fatigue. All of these issues have impacted all of our lives to some degree. Many of us have
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
Falling platelet counts after achieving Undetectable Minimal Residual Diseaese
Hello folks I completed a course of Venetoclax & Obinituzumab (Gazyva) last March, and happily achieved UMRD (undetectable minimal residual disease). I'm part of a clinical trial, which stopped treatment once I reached UMRD (with a minimum of 6-9 months of treatment); I was treated for 9 months. Have
Hello folks I completed a course of Venetoclax & Obinituzumab (Gazyva) last March, and happily achieved UMRD (undetectable minimal residual disease). I'm part of a clinical trial, which stopped treatment once I reached UMRD (with a minimum of 6-9 months of treatment); I was treated for 9 months. Have
DinosaurDad
in
CLL Support
4 months ago
Heart rate up and down
my husband is currently waiting for an appointment with the arrhythmia clinic after suffering a stroke 3 months ago . As I’ve mentioned before he had an ablation in 2017 which had obviously stopped working at some point . Just curious as to whether anyone else s heart rate varies so much . He can go
my husband is currently waiting for an appointment with the arrhythmia clinic after suffering a stroke 3 months ago . As I’ve mentioned before he had an ablation in 2017 which had obviously stopped working at some point . Just curious as to whether anyone else s heart rate varies so much . He can go
Jackiesmith7777
in
AF Association
10 months ago
Cardiovascular disease (CVD) kills more than 20.5 million people every year across the world
Did you know atrial fibrillation (AF) is the most common heart rhythm disorder and leading cause of stroke? Over 1.5 million people in the UK are diagnosed with AF and yet approx. a further 500,000 yet to be diagnosed. A simple pulse check can DETECT AF. Anticoagulation therapy can PROTECT against
Did you know atrial fibrillation (AF) is the most common heart rhythm disorder and leading cause of stroke? Over 1.5 million people in the UK are diagnosed with AF and yet approx. a further 500,000 yet to be diagnosed. A simple pulse check can DETECT AF. Anticoagulation therapy can PROTECT against
TracyAdmin
Partner
in
AF Association
10 months ago
OCD Institute - Houston
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
My adult son was recently referred to the OCD Institute in Houston for residential treatment. Has anyone had success there or can anyone share their experience there? He has been in outpatient treatment since the beginning of January and so far it is not working well. We are looking for any help we can
BrooksideBliss
in
My OCD Community
4 months ago
slow release liothyronine
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Like many people on here I miss the wise opinion and knowledge of Diogenes enormously. I know he was working on the formulation of a slow release liothyronine which was in clinical trial. Does anyone have an update on this? is it any closer? In the meantime I am tempted to try sustained release compounded
Mollyfan
in
Thyroid UK
4 months ago
Lisinopril, A-Fib enlarged left atrium,
I was taking Diltiazem 60 mg 12HR ER Cap 2 times a day for A-fib and hypertension. I stopped it as doctor recommended when I had to take Paxlovid for Covid. I didn't get A-fib when I didn't go back to taking the Diltiazem and have been off of it for more than 2 months. I'm thinking of taking Lisinopril
I was taking Diltiazem 60 mg 12HR ER Cap 2 times a day for A-fib and hypertension. I stopped it as doctor recommended when I had to take Paxlovid for Covid. I didn't get A-fib when I didn't go back to taking the Diltiazem and have been off of it for more than 2 months. I'm thinking of taking Lisinopril
Jana_
in
AF Association
10 months ago
Lisinopril enlarged Atrium, afib
Jana_ in reply to BobD 7 days ago I was taking Diltiazem 60 mg 12HR ER Cap 2 times a day for A-fib and hypertension. I stopped it as doctor recommended when I had to take Paxlovid for Covid. I didn't get A-fib when I didn't go back to taking the Diltiazem and have been off of it for more than
Jana_ in reply to BobD 7 days ago I was taking Diltiazem 60 mg 12HR ER Cap 2 times a day for A-fib and hypertension. I stopped it as doctor recommended when I had to take Paxlovid for Covid. I didn't get A-fib when I didn't go back to taking the Diltiazem and have been off of it for more than
Jana_
in
AF Association
10 months ago
Smell Training (Olfactory Training)
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Smell Training (Olfactory Training)
March 18, 2024
This post is about Smell Training and is building on an earlier HU post “Olfactory enrichment improves olfactory ability in humans with olfactory loss due to Parkinson’s”
https://healthunlocked.com/cure-parkinsons/posts/150588869/olfactory-enrichment-improves-olfactory-ability-in-humans-with-olfactory-loss-due-to-parkinson-s
Bolt_Upright
in
Cure Parkinson's
4 months ago
Seeking anyone familiar with aggressive small cell neuroendocrine prostate cancer and/or with lurbinectedin as 2nd line chemotherapy.
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
silver5
in
Advanced Prostate Cancer
4 months ago
Weighing the pros and possible risks of treatment holiday.
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
I am looking for reliable articles (not too scientific please). We will be discussing w oncologist this week and again with his clinical trial people next month. My husband's only treatment has been 1st & 2nd generation hormone therapy (Eligard & Darolutamide) for 20 months. He reached >.1 nadar
Decktime
in
Advanced Prostate Cancer
4 months ago
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