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Arginine / Lysine

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Lysine And Covid-19, Cut The Crap!

HSV growth in both cell and tissue cultures that were supplemented with arginine was suppressed upon the addition of lysine [22].
HSV growth in both cell and tissue cultures that were supplemented with arginine was suppressed upon the addition of lysine [22].
chartist profile image
chartist
in Cure Parkinson's

IBS general: my experience

This smell of rotting flesh comes from the amino acids lysine and arginine being metabolized by bad colonic bacteria into cadaverine and putrescine – the compounds that give the characteristic smell of death!
This smell of rotting flesh comes from the amino acids lysine and arginine being metabolized by bad colonic bacteria into cadaverine and putrescine – the compounds that give the characteristic smell of death!
Stuart24 profile image
Stuart24
in IBS Network

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
Here is one out of far left field https://www.frontiersin.org/articles/10.3389/fphar.2021.692574/full PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy www.frontiersin.orgSi-Min Qi1†, www.frontiersin.orgJinyun Dong2†, www.frontiersin.orgZhi-Yuan Xu2, www.frontiersin.orgXiang-Dong
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Scout4answers
in Advanced Prostate Cancer
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NAC supp continued

I've been taking it (N-acetyl cysteine) with Dr approval. I tried two short tests last Dec and it seemed to help. My latest test has been going for ~ 2 months and is less obviously successful. At the start in Feb I took 600 mgm while I was still on HU only, at 500. My symptoms got worse (usual malaise
I've been taking it (N-acetyl cysteine) with Dr approval. I tried two short tests last Dec and it seemed to help. My latest test has been going for ~ 2 months and is less obviously successful. At the start in Feb I took 600 mgm while I was still on HU only, at 500. My symptoms got worse (usual malaise
EPguy profile image
EPguy
in MPN Voice

Cortexyme presented new data from their Phase II/III GAIN trial of atuzaginstat in mild/moderate Alzheimers

Cortexyme presented new data from their Phase II/III GAIN trial of atuzaginstat in mild/moderate #Alzheimers at adpdnet meeting, showing the drug inhibited lysine gingipains, plus 30%-50% slowing in cognitive decline in high P. gigivalis load cases https://www.cortexyme.com/cortexyme-provides-new-gain-trial-data-at-ad-pd
Cortexyme presented new data from their Phase II/III GAIN trial of atuzaginstat in mild/moderate #Alzheimers at adpdnet meeting, showing the drug inhibited lysine gingipains, plus 30%-50% slowing in cognitive decline in high P. gigivalis load cases https://www.cortexyme.com/cortexyme-provides-new-gain-trial-data-at-ad-pd
nedim profile image
nedim
in Cure Parkinson's

Besremi versus Pegasys

This question was raised by Flynn2107 months ago. I looked into it and replied there but it seems worth a new post with the recent FDA approval. PEG and Ropeg (Besremi) use polyethylene glycol (PEG) to control the release of the INF molecule. The earliest INFs had less of a control element and more
This question was raised by Flynn2107 months ago. I looked into it and replied there but it seems worth a new post with the recent FDA approval. PEG and Ropeg (Besremi) use polyethylene glycol (PEG) to control the release of the INF molecule. The earliest INFs had less of a control element and more
EPguy profile image
EPguy
in MPN Voice

Salmon Protein Hydrolysate

It contains particularly high amounts of glutamic acid (13.9 g/100 g), aspartic acid (9.4 g/100 g), glycine (14.9 g/100 g), proline (7.6 g/100 g), lysine (7.0 g/100 g), alanine (7.5 g/100 g) and arginine (6.9 g/100 g).
It contains particularly high amounts of glutamic acid (13.9 g/100 g), aspartic acid (9.4 g/100 g), glycine (14.9 g/100 g), proline (7.6 g/100 g), lysine (7.0 g/100 g), alanine (7.5 g/100 g) and arginine (6.9 g/100 g).
pjoshea13 profile image
pjoshea13
in Advanced Prostate Cancer

Sirtuins and Pd

For lovers of the genre, an interesting research on Sirtuins and PD. Very specialized and technical. From SoP. "Abstract The sirtuin (SIRT) protein family has been of major research interest over the last decades because of their involvement in aging, cancer, and cell death. SIRTs have been implicated
For lovers of the genre, an interesting research on Sirtuins and PD. Very specialized and technical. From SoP. "Abstract The sirtuin (SIRT) protein family has been of major research interest over the last decades because of their involvement in aging, cancer, and cell death. SIRTs have been implicated
Gioc profile image
Gioc
in Cure Parkinson's

Low-carb diet - ketogenesis - PSADT

New study from Steve Freedland et al. "Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial" [1] Bottom line: Low-carb diet may lenghthen
New study from Steve Freedland et al. "Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial" [1] Bottom line: Low-carb diet may lenghthen
pjoshea13 profile image
pjoshea13
in Advanced Prostate Cancer

Supplements for C-myelopathy

I started taking B1-500 mg and B complex-50 mg. and B12 sometime ago when I didn't know what was happening. I added other supplements like lysine, tyrosine, phosphatidyl choline and Vit. E, D, krill oil, zinc, etc. and without these energy and ataxia are much worse. I just joined so wanting to know
I started taking B1-500 mg and B complex-50 mg. and B12 sometime ago when I didn't know what was happening. I added other supplements like lysine, tyrosine, phosphatidyl choline and Vit. E, D, krill oil, zinc, etc. and without these energy and ataxia are much worse. I just joined so wanting to know
rideabike profile image
rideabike
in Cervical Myelopathy

Microbiomes of Urine and the Prostate Are Linked to Human Prostate Cancer Risk Groups

I have stayed away from this topic, but so many have posted & I don't think a link to the actual paper has been given. Apologies if not the case. Anyway, https://pubmed.ncbi.nlm.nih.gov/35450835/ Eur Urol Oncol . 2022 Apr 18;S2588-9311(22)00056-6. doi: 10.1016/j.euo.2022.03.006. Online ahead
I have stayed away from this topic, but so many have posted & I don't think a link to the actual paper has been given. Apologies if not the case. Anyway, https://pubmed.ncbi.nlm.nih.gov/35450835/ Eur Urol Oncol . 2022 Apr 18;S2588-9311(22)00056-6. doi: 10.1016/j.euo.2022.03.006. Online ahead
pjoshea13 profile image
pjoshea13
in Advanced Prostate Cancer

The Role Of Bile Acids In Prostate Cancer

Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Bile acids (BAs) belong to cholesterol-derived sterols. Due to the side chain carboxyl group and hydroxylation of their steroid ring they are more polar than cholesterol. They have an amphipatic character for which they are known as natural detergents. Majority of cholesterol is excreted by bile acids
Hidden profile image
Hidden
in Advanced Prostate Cancer

A Wise Person Told Me to Not Forget About TUDCA

Bile Acid Signaling in Neurodegenerative and Neurological Disorders 2020 https://mdpi-res.com/d_attachment/ijms/ijms-21-05982/article_deploy/ijms-21-05982.pdf "4.2. Parkinson’s Disease After AD, Parkinson’s disease (PD) is the second most common neurodegenerative disease marked by progressive motor deterioration
Bile Acid Signaling in Neurodegenerative and Neurological Disorders 2020 https://mdpi-res.com/d_attachment/ijms/ijms-21-05982/article_deploy/ijms-21-05982.pdf "4.2. Parkinson’s Disease After AD, Parkinson’s disease (PD) is the second most common neurodegenerative disease marked by progressive motor deterioration
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

The Neuroendocrine Connection

Adrenal hormones, sex hormones, and neurotransmitters are functionally interrelated. Changes in sex hormones and adrenal hormones can lead to neurotransmitter imbalances. In turn, neurotransmitter imbalances can affect hormone function. The following tests are recommended to establish your baseline.
Adrenal hormones, sex hormones, and neurotransmitters are functionally interrelated. Changes in sex hormones and adrenal hormones can lead to neurotransmitter imbalances. In turn, neurotransmitter imbalances can affect hormone function. The following tests are recommended to establish your baseline.
SilentEchoes profile image
SilentEchoes
in Cure Parkinson's

Comprehensive urinary metabolomic profiling and identification of potential noninvasive marker for idiopathic Parkinson’s disease

Box plot showing levels of representative metabolites in normal controls (CON), early-stage PD (EPD), mid-stage PD (MPD) and advanced-stage PD (APD). (A) leucine, (B) isoleucine, (C) glycine, (D) cortisol, (E) dihydrocortisol, (F) kynurenine, (G) phenylalanine; (H) acetylphenylalanine. Asterisk(*) denotes
Box plot showing levels of representative metabolites in normal controls (CON), early-stage PD (EPD), mid-stage PD (MPD) and advanced-stage PD (APD). (A) leucine, (B) isoleucine, (C) glycine, (D) cortisol, (E) dihydrocortisol, (F) kynurenine, (G) phenylalanine; (H) acetylphenylalanine. Asterisk(*) denotes
Bolt_Upright profile image
Bolt_Upright
in Cure Parkinson's

"Low oxalate" may be the only true solution

Before you read the following please take a moment and imagine how frustrating it is for someone to have figured out a non-medical treatment for RLS and then had very little luck getting anybody to listen to him. Every day this website carries stories of needless suffering and it breaks my heart. For
Before you read the following please take a moment and imagine how frustrating it is for someone to have figured out a non-medical treatment for RLS and then had very little luck getting anybody to listen to him. Every day this website carries stories of needless suffering and it breaks my heart. For
notnowdad profile image
notnowdad
in Restless Legs Syndrome

Want to mange this thing!

I had catheter ablation for supraventricular Tachycardia in March and second one in June. Was told 2nd ablation would fix me, as the Electrophysiologist now knew what to do/where to ablate and would use special mapping equipment and higher powered catheters. He ablated SVT site and found a Flutter site
I had catheter ablation for supraventricular Tachycardia in March and second one in June. Was told 2nd ablation would fix me, as the Electrophysiologist now knew what to do/where to ablate and would use special mapping equipment and higher powered catheters. He ablated SVT site and found a Flutter site
Fabfibber profile image
Fabfibber
in AF Association

Supplements to give up after Bfp

Hi there, after 3 failed transfers I’ve managed to get a bfp when trying naturally, I’ve also had 3 chemical pregnancies. I’m very nervous about stopping the supplements I’ve been taking - l-arginine, inositol,CoQ10 and 75mg aspirin along with pregnacare multi vitamin and extra vit d. Is it safe to just
Hi there, after 3 failed transfers I’ve managed to get a bfp when trying naturally, I’ve also had 3 chemical pregnancies. I’m very nervous about stopping the supplements I’ve been taking - l-arginine, inositol,CoQ10 and 75mg aspirin along with pregnacare multi vitamin and extra vit d. Is it safe to just
Lozz566 profile image
Lozz566
in Fertility Network UK

Prep for FET (thin lining)

Hi team, I've tried to look this question up but I am going round in circles a bit. For people who took/take vitamin E and L-Arginine supplements to prep for a FET (thin lining issues here!) when did you start to take these? I can't quite remember what I did last time but I'm pretty sure I started vitamin
Hi team, I've tried to look this question up but I am going round in circles a bit. For people who took/take vitamin E and L-Arginine supplements to prep for a FET (thin lining issues here!) when did you start to take these? I can't quite remember what I did last time but I'm pretty sure I started vitamin
Hoop123 profile image
Hoop123
in Fertility Network UK

Ashermans, thin lining, low ovarian reserve, poor responder.. trying ivf one last time with donor sperm for possible surrogacy if lucky

After many years of having a Mirena coil for heavy periods, my then partner and I decided to start to try for a baby. I thought it was strange that when I had the coil out my periods remained just as light as when I had it in. I decided to do some hormone tests, and discovered I had a high prolactin
After many years of having a Mirena coil for heavy periods, my then partner and I decided to start to try for a baby. I thought it was strange that when I had the coil out my periods remained just as light as when I had it in. I decided to do some hormone tests, and discovered I had a high prolactin
Hidden profile image
Hidden
in Infertility Support
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