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Current advances of liquid biopsies in prostate cancer: Molecular biomarkers, Cell/Molecular Therapy Oncolytics, 09/21/23
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
CaptnMojoe
in
Fight Prostate Cancer
10 months ago
Provenge Underway
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Pmann
in
Advanced Prostate Cancer
10 months ago
ADT + Zytiga holiday???
I've been on Orgovyx since 8/15/22 and Zytiga since 4/1/23. I'm also suffering from neuropathy from nerve damage that occurred in December 22. The nerve pain has gotten worse and my oncologist and neurologist are wondering if ADT or Zytiga are too blame. Anyone have experience with these drugs and
I've been on Orgovyx since 8/15/22 and Zytiga since 4/1/23. I'm also suffering from neuropathy from nerve damage that occurred in December 22. The nerve pain has gotten worse and my oncologist and neurologist are wondering if ADT or Zytiga are too blame. Anyone have experience with these drugs and
VanHalen84
in
Advanced Prostate Cancer
10 months ago
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New meta-analysis shows docetaxel benefits those having high grade/low PSA prostate cancer
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
HikerWife
in
Advanced Prostate Cancer
10 months ago
Docetaxel only partially successful
I had a full body MRI scan this week at Royal Marsden in London. The purpose was to assess the effectiveness of docetaxel after 3 infusions. The results have been very disappointing, and I'm struggling to keep a sense of perspective - not least because I was feeling so good, and had seen all of my previous
I had a full body MRI scan this week at Royal Marsden in London. The purpose was to assess the effectiveness of docetaxel after 3 infusions. The results have been very disappointing, and I'm struggling to keep a sense of perspective - not least because I was feeling so good, and had seen all of my previous
CrocodileShoes
in
Advanced Prostate Cancer
10 months ago
tumor in spleen
my husband is having his spleen out very soon due to 2 tumors. We won’t know for sure if they are cancer until pathology done. He had radiation plus Lupron and has been in remission 2 years. 4 + 4 Psa still non detectable. Tumors picked up on pet scan to check kidney. Radiologist has said rare
my husband is having his spleen out very soon due to 2 tumors. We won’t know for sure if they are cancer until pathology done. He had radiation plus Lupron and has been in remission 2 years. 4 + 4 Psa still non detectable. Tumors picked up on pet scan to check kidney. Radiologist has said rare
Ojsm
in
Advanced Prostate Cancer
10 months ago
ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Scout4answers
in
Advanced Prostate Cancer
10 months ago
PSMA PET scan
Hello everyone, pardon the simplicity of my question. Is PSMA the same as PET Scan? I ask this because I specifically asked my MO to have a PSMA pet scam but no where in the order or appointment a mention of PSMA pet scan it only says pet scan. I am concerned because MO doesn't seem to be very involved
Hello everyone, pardon the simplicity of my question. Is PSMA the same as PET Scan? I ask this because I specifically asked my MO to have a PSMA pet scam but no where in the order or appointment a mention of PSMA pet scan it only says pet scan. I am concerned because MO doesn't seem to be very involved
Blueribbon63
in
Advanced Prostate Cancer
10 months ago
castration after 7 years of ADT
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
Roscoaus2000
in
Advanced Prostate Cancer
10 months ago
Is my cancer castrate resistant?
Since detection of abdominal and pelvic mesastasis by PSMA scan in October 2018, intermittant Lupron was very effective in keeping my cancer under control until July 2022. From July 2022 until now I have been on continuous Lupron because PSA refused to become undetectable. From July 2022 until August
Since detection of abdominal and pelvic mesastasis by PSMA scan in October 2018, intermittant Lupron was very effective in keeping my cancer under control until July 2022. From July 2022 until now I have been on continuous Lupron because PSA refused to become undetectable. From July 2022 until August
dac500
in
Advanced Prostate Cancer
10 months ago
Pluvicto Failed - Next step
Hello Warriors: Pluvicto has failed. I went through four sessions and had severe side effects of exhaustion and GI problems as well as it seemed to stimulate my foot neuropathy. My PSA went down during injection 2 and 3 but then came back up in 4. Disappointing... I just met my new MO at the Mayo
Hello Warriors: Pluvicto has failed. I went through four sessions and had severe side effects of exhaustion and GI problems as well as it seemed to stimulate my foot neuropathy. My PSA went down during injection 2 and 3 but then came back up in 4. Disappointing... I just met my new MO at the Mayo
Hidden
in
Advanced Prostate Cancer
10 months ago
Cavernous Tumor & Rising PSA
My husband had triple therapy with docetaxel (finished chemo in January), darolutimide, and Firmagon/Lupron. Recently he developed what seemed like a sinus infection but was really a tumor in his sinus cavity and behind his eye socket wrapped around his carotid arteries on the plate of his skull (
My husband had triple therapy with docetaxel (finished chemo in January), darolutimide, and Firmagon/Lupron. Recently he developed what seemed like a sinus infection but was really a tumor in his sinus cavity and behind his eye socket wrapped around his carotid arteries on the plate of his skull (
Izzygirl1
in
Advanced Prostate Cancer
10 months ago
Relugolix and Apalutamide
Any experience with elevated AST and ALT after being treated with Relugolix and Apalutamide? My AST and ALT were normal on Relugolix for 6 weeks.....added Apalutamide and after 4 weeks my AST and ALT are now 3X previous level. I feel fine. Oncologist is wanting to stop the one of the drugs.....I convinced
Any experience with elevated AST and ALT after being treated with Relugolix and Apalutamide? My AST and ALT were normal on Relugolix for 6 weeks.....added Apalutamide and after 4 weeks my AST and ALT are now 3X previous level. I feel fine. Oncologist is wanting to stop the one of the drugs.....I convinced
GoLowPSA
in
Advanced Prostate Cancer
10 months ago
What a long strange road it's been.
Nov 2007 I had DaVinci surgery Gleason 7. I got the surgeon's notes and he said margins were clear, took s bunch of lymph glands, all clear. Held my dick in his hand and said it would come back. It did, but never quite lost the "happy bladder" and I shot pee about 50% of the time. PSA never went
Nov 2007 I had DaVinci surgery Gleason 7. I got the surgeon's notes and he said margins were clear, took s bunch of lymph glands, all clear. Held my dick in his hand and said it would come back. It did, but never quite lost the "happy bladder" and I shot pee about 50% of the time. PSA never went
bcskibdy
in
Prostate Cancer And Gay Men
10 months ago
Side effects experienced once you add Zytiga to Orgovyx
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
CancerConcierge
in
Advanced Prostate Cancer
10 months ago
Update: PSA after IMRT
After my 40 treatments, I wanted to get off the bicalutamide I had been on for 2 months. My breasts had not only gotten enlarged but they had also become quite painful, and the Tamoxifen my RO had put me on did not help with this. He then ordered an early PSA test, and when it came back at just .12
After my 40 treatments, I wanted to get off the bicalutamide I had been on for 2 months. My breasts had not only gotten enlarged but they had also become quite painful, and the Tamoxifen my RO had put me on did not help with this. He then ordered an early PSA test, and when it came back at just .12
Smarks42
in
Prostate Cancer Network
10 months ago
Medical Oncologists recommendations at Mayo Phoenix
My husband is being treated for high risk prostate cancer at Mayo, Phoenix.. GL 9, PSA 46.6 ( almost finished with Proton radiation treatments, on Orgovyx and will be starting on Zytiga. He has had one consult with a Mayo MO , but it wasn’t a good fit. Would be grateful if anyone who was treated at
My husband is being treated for high risk prostate cancer at Mayo, Phoenix.. GL 9, PSA 46.6 ( almost finished with Proton radiation treatments, on Orgovyx and will be starting on Zytiga. He has had one consult with a Mayo MO , but it wasn’t a good fit. Would be grateful if anyone who was treated at
CancerConcierge
in
Advanced Prostate Cancer
10 months ago
PSA At Very Low Levels But Starting to Rise
My PSA started to rise from undetectable up to about .36 in July 2021 after 9 years of treatment. My MO reviewed a PSMA and decided to have my largest tumor radiated. My PSA went below .05 once again shortly thereafter. My most recent PSA labs were : .05, .06, .06, and .09 last week. I am conferring
My PSA started to rise from undetectable up to about .36 in July 2021 after 9 years of treatment. My MO reviewed a PSMA and decided to have my largest tumor radiated. My PSA went below .05 once again shortly thereafter. My most recent PSA labs were : .05, .06, .06, and .09 last week. I am conferring
jfoesq
in
Advanced Prostate Cancer
10 months ago
Radiation Question
PSA test sent me into this journey about 8 mos ago, Gleason 6-7-8s, good PSMA PET/CT did not show uptake outside of the prostate, 6 mos now on Abiraterone and Zytiga brought PSA to .31, now suggesting radiation, went to see RO and they want to start right away, 8 weeks x-ray type to include abdomen in
PSA test sent me into this journey about 8 mos ago, Gleason 6-7-8s, good PSMA PET/CT did not show uptake outside of the prostate, 6 mos now on Abiraterone and Zytiga brought PSA to .31, now suggesting radiation, went to see RO and they want to start right away, 8 weeks x-ray type to include abdomen in
jgsdone
in
Advanced Prostate Cancer
10 months ago
Post RP/SRT Pelvic Mass?
RRP 2/02, SRT 7/16, BCR 9/23 Latest PSA .17 I recently retired and have been spending more time sitting on my ass in front of the computer [like right now] than I should. Over the last couple of months I have begun to feel/sense that I am sitting on something, very similar to what I felt pre-RP. At
RRP 2/02, SRT 7/16, BCR 9/23 Latest PSA .17 I recently retired and have been spending more time sitting on my ass in front of the computer [like right now] than I should. Over the last couple of months I have begun to feel/sense that I am sitting on something, very similar to what I felt pre-RP. At
bldn10
in
Advanced Prostate Cancer
10 months ago
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