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Bone Problems
4 years on ADT and Abiraterone. Had spine fracture and now have osteopenia due to medication. has anyone else suffered bone issues with this medication.
4 years on ADT and Abiraterone. Had spine fracture and now have osteopenia due to medication. has anyone else suffered bone issues with this medication.
Lion321
in
Advanced Prostate Cancer
2 years ago
Collagen Peptide supplements and bone quality
Y'all are familiar by now that ADT leads to accelerated BMD (bone mineral density) loss. There are a series of things that can be done -- 1, Get a DEX scan now 2, Supplement with Calcium, K2, D3 and magnesium 3, Have your MO or whoever put you on BMD medication (eg denosumab, et al) Now comes
Y'all are familiar by now that ADT leads to accelerated BMD (bone mineral density) loss. There are a series of things that can be done -- 1, Get a DEX scan now 2, Supplement with Calcium, K2, D3 and magnesium 3, Have your MO or whoever put you on BMD medication (eg denosumab, et al) Now comes
Derf4223
in
Advanced Prostate Cancer
2 years ago
ADT and ED Meds?
I am just starting Orgovyx and it's working well.... too well as far as ED is concerned. I had no significant issues prior to ADT with achieving an erection and orgasm. So at a minimum I'm pretty motivated to try and get it back in some form or fashion or at least do whatever I can prophylactically
I am just starting Orgovyx and it's working well.... too well as far as ED is concerned. I had no significant issues prior to ADT with achieving an erection and orgasm. So at a minimum I'm pretty motivated to try and get it back in some form or fashion or at least do whatever I can prophylactically
FinnO
in
Advanced Prostate Cancer
2 years ago
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question about hypothermia?
a couple weeks back, I visited my Kaiser infusion lab …. Lupron implant and Zometa pain train infusion. While there the intake nurse was alarmed with my 95.2 body temp. It’s been running between 95.2 and 95.7 lately. She told me to go to the E.R. , immediately, if it dropped to 95 or less. They were
a couple weeks back, I visited my Kaiser infusion lab …. Lupron implant and Zometa pain train infusion. While there the intake nurse was alarmed with my 95.2 body temp. It’s been running between 95.2 and 95.7 lately. She told me to go to the E.R. , immediately, if it dropped to 95 or less. They were
Kaliber
in
Advanced Prostate Cancer
2 years ago
ADT Emotional Lability Do Antidepressants Help?
Dear All, I’m dealing with the emotional lability of ADT and was wondering if Antidepressants helped? Just curious about others experiences. I have tried escitalopram but was deathly nauseous 3 days in and stopped taking it and haven’t tried anything else. Thank you for sharing your experiences.
Dear All, I’m dealing with the emotional lability of ADT and was wondering if Antidepressants helped? Just curious about others experiences. I have tried escitalopram but was deathly nauseous 3 days in and stopped taking it and haven’t tried anything else. Thank you for sharing your experiences.
TylexGP
in
Advanced Prostate Cancer
2 years ago
AR-V7 blood test and PET ordered yesterday.
MO diagnosis information on test order form (slightly edited) is: "Metastatic (stage IV), castrate resistant prostate cancer at last visit. (YES). Most recent PSA .25. Date 1-23-23. Patient received and failed either Xtandi, Erleada or Zytiga and progression of mCRPC was defined by the Prostate Cancer
MO diagnosis information on test order form (slightly edited) is: "Metastatic (stage IV), castrate resistant prostate cancer at last visit. (YES). Most recent PSA .25. Date 1-23-23. Patient received and failed either Xtandi, Erleada or Zytiga and progression of mCRPC was defined by the Prostate Cancer
alperk
in
Advanced Prostate Cancer
2 years ago
Oral SERD approved by FDA
https://apple.news/Ai1FWYlHCQ_yIOAT6MGXX6w Hormone therapies are well established in breast cancer treatment, working by blocking or reducing levels of hormones that feed tumor growth. If the disease progresses, the next line of therapy includes an injectable drug that specifically targets the estrogen
https://apple.news/Ai1FWYlHCQ_yIOAT6MGXX6w Hormone therapies are well established in breast cancer treatment, working by blocking or reducing levels of hormones that feed tumor growth. If the disease progresses, the next line of therapy includes an injectable drug that specifically targets the estrogen
Kerryd22
in
SHARE Metastatic Breast Cancer
2 years ago
To ARi or not to ARi, that is the question
I had a 12/22 .71 PSA, 6mo doubling time and PSMA confirmed 5mm met in right pelvic lymph node (after prior failure of RP and fossa IMRT to “cure”). I have been on Orgovyx for a month and start 28 sessions of IMRT to the pelvic lymph nodes with boost to known met next week. Tolerating Orgovyx very well
I had a 12/22 .71 PSA, 6mo doubling time and PSMA confirmed 5mm met in right pelvic lymph node (after prior failure of RP and fossa IMRT to “cure”). I have been on Orgovyx for a month and start 28 sessions of IMRT to the pelvic lymph nodes with boost to known met next week. Tolerating Orgovyx very well
FinnO
in
Advanced Prostate Cancer
2 years ago
Relugolix/Orgovyx with pelvic radiation?
My PSA is increasing once again beyond the detectable level. 9 years ago had RPT. 6 years ago had follow up PBRT only upon a detectable psa rise. See history in profile. My recent PSA is at 0.364. I have a PSMA PET scan scheduled at UCSF in April. Should the scan show metastasis in the pelvic
My PSA is increasing once again beyond the detectable level. 9 years ago had RPT. 6 years ago had follow up PBRT only upon a detectable psa rise. See history in profile. My recent PSA is at 0.364. I have a PSMA PET scan scheduled at UCSF in April. Should the scan show metastasis in the pelvic
bitittle
in
Advanced Prostate Cancer
2 years ago
QOL - Even More Handy APC Euphemisms
Every once in a while (24/7) my brain takes a dive into black humor. I know this type of humor isn’t for everyone, but hopefully the rest of you will find a chuckle or two to brighten the day. [u]
Even More Handy APC Euphemisms
[/u] for Patients and Their Families
1. Wee Willie, Shorty
Every once in a while (24/7) my brain takes a dive into black humor. I know this type of humor isn’t for everyone, but hopefully the rest of you will find a chuckle or two to brighten the day. [u]
Even More Handy APC Euphemisms
[/u] for Patients and Their Families
1. Wee Willie, Shorty
Carlosbach
in
Advanced Prostate Cancer
2 years ago
Keynote trial of Pembrolizumab + Enz+ ADT discontinued
You might have already seen this but for those like me, Just read this news. Disappointing results of trial https://www.businesswire.com/news/home/20230124006084/en/Merck-Announces-KEYNOTE-991-Trial-Evaluating-KEYTRUDA%C2%AE-pembrolizumab-Plus-Enzalutamide-and-Androgen-Deprivation-Therapy-in-Patients-With-Metastatic-Hormone-Sensitive-Prostate-Cancer-to-Stop-for-Futility
You might have already seen this but for those like me, Just read this news. Disappointing results of trial https://www.businesswire.com/news/home/20230124006084/en/Merck-Announces-KEYNOTE-991-Trial-Evaluating-KEYTRUDA%C2%AE-pembrolizumab-Plus-Enzalutamide-and-Androgen-Deprivation-Therapy-in-Patients-With-Metastatic-Hormone-Sensitive-Prostate-Cancer-to-Stop-for-Futility
Fightinghard
in
Advanced Prostate Cancer
2 years ago
Who else has Myelodysplastic Syndromes (MDS) in addition to their PCa?
Dx a month ago as having trilineage MDS with Ring Sideroblasts(MDS-RS), somewhere between low and intermediate. Described as bone marrow cancers and a bone marrow biopsy is required for dx. It morphs into Acute Myloid Leukemia in 30-40% of the cases. Know that my shit is weak and am searching for
Dx a month ago as having trilineage MDS with Ring Sideroblasts(MDS-RS), somewhere between low and intermediate. Described as bone marrow cancers and a bone marrow biopsy is required for dx. It morphs into Acute Myloid Leukemia in 30-40% of the cases. Know that my shit is weak and am searching for
SpencerBoy11
in
Advanced Prostate Cancer
2 years ago
Curcumin (Theracurmin) Improves Mild Cognitive Impairment and Memory - A Randomized Clinical Trial
This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
MateoBeach
in
Fight Prostate Cancer
2 years ago
Is this a rare event?
Diagnosed in 2006, Gleason 7, failed surgery, failed salvage radiation by beginning of 2007. Saw Tanya Dorff in USC and was put on triple hormone therapy with 90 day lupron. and Casodex and Avodart Dorff believed in intermittent therapy and was i was given a holiday from treatment if psa and testosterone
Diagnosed in 2006, Gleason 7, failed surgery, failed salvage radiation by beginning of 2007. Saw Tanya Dorff in USC and was put on triple hormone therapy with 90 day lupron. and Casodex and Avodart Dorff believed in intermittent therapy and was i was given a holiday from treatment if psa and testosterone
arizonablue
in
Advanced Prostate Cancer
2 years ago
Why do my feet and ankles stay swollen while on ADT therapy
Why do my feet and ankles stay swollen while on ADT therapy
Why do my feet and ankles stay swollen while on ADT therapy
barryium
in
Advanced Prostate Cancer
2 years ago
Strength Training Problem; Advice?
I know that many of you are well practiced in the art and science of strength training, so I’m hoping you might be able to help me here. My only therapy for mPC DX 4 years ago has been ADT (Lupron & abiraterone). So far so good in that my PSA remains < 0.1 and occasional imaging indicates that my upper
I know that many of you are well practiced in the art and science of strength training, so I’m hoping you might be able to help me here. My only therapy for mPC DX 4 years ago has been ADT (Lupron & abiraterone). So far so good in that my PSA remains < 0.1 and occasional imaging indicates that my upper
Gearhead
in
Advanced Prostate Cancer
2 years ago
protocol for intermittent ADT
so his psa rose after 2.5years of an ADT holiday and he took casodex for 4 weeks then had a 3 month zoladex implant , after 2 months he is undetectable again , we asked his oncologist what the protocol is for length of time on it this time and he said if he stayed undetectable that he could possibly
so his psa rose after 2.5years of an ADT holiday and he took casodex for 4 weeks then had a 3 month zoladex implant , after 2 months he is undetectable again , we asked his oncologist what the protocol is for length of time on it this time and he said if he stayed undetectable that he could possibly
Merlin1960
in
Advanced Prostate Cancer
2 years ago
Is anyone currently doing TRT or BAT?
I was dx'd stage 4, G8 in 2018, at age 49, after 44 EBRT sessions and one year of ADT/lupron, I rejected any further ADT after experiencing horrible, life altering side effects and learning about it's actual efficacy. My PSA kept rising ever so slightly, so I pushed for a PSMA PET scan for two years
I was dx'd stage 4, G8 in 2018, at age 49, after 44 EBRT sessions and one year of ADT/lupron, I rejected any further ADT after experiencing horrible, life altering side effects and learning about it's actual efficacy. My PSA kept rising ever so slightly, so I pushed for a PSMA PET scan for two years
babaxiong
in
Advanced Prostate Cancer
2 years ago
Portugese doctors' use of T4 and T3 therapy
A look now at Portugese doctors' treatment of hypothyroidism. They are much less likely to prescribe combination therapy, but many would consider it if the patient did not improve on T4 only. They aren't interested in the source of T4.
Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients
A look now at Portugese doctors' treatment of hypothyroidism. They are much less likely to prescribe combination therapy, but many would consider it if the patient did not improve on T4 only. They aren't interested in the source of T4.
Use of Thyroid Hormones in Hypothyroid and Euthyroid Patients
diogenes
in
Thyroid UK
2 years ago
In hospital with neutropenia following 1st cycle of Docetaxel. Considering discontinuing Docetaxel, is that reasonable?
Gl 5+4 Adjusted PSA at diagnosis of 27 ( was on Dutasteride) cT2 N1 M0 . Pelvic and para aortic nodes on PMSA PET scan . Started on ADT in October 22. PSA < 0.03 in January after 3 months of ADT, pre starting Docetaxel. 8th day following 1st dose of Doctaxel, fever, landed in hospital with severe
Gl 5+4 Adjusted PSA at diagnosis of 27 ( was on Dutasteride) cT2 N1 M0 . Pelvic and para aortic nodes on PMSA PET scan . Started on ADT in October 22. PSA < 0.03 in January after 3 months of ADT, pre starting Docetaxel. 8th day following 1st dose of Doctaxel, fever, landed in hospital with severe
Jay-kud8
in
Advanced Prostate Cancer
2 years ago
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