Current Trial; 1.5mg methylcobalamin 3mg/ml, 1.5mg adenosylcobalamin 3mg/ml, 1.5mg hydroxocobalamin 3mg/ml. SC injection 5 times a day. 50 mg B6 in the form of P-5-P three times a day or pain from peripheral neuropathy returns. Benfotiamin B1 300 mg 5 times a day. 2 mg Magnesium L-Threonate twice a day to prevent muscle cramps. Betiane 5 times a day total 20 mg.
“Betaine is used to lower homocysteine as a substrate for betaine‐homocysteine methyltransferase, which can convert homocysteine into methionine.”
“ betaine at 250 mg/kg/day”
The above two quotes are from ncbi.nlm.nih.gov/pmc/articl...
I first came across betaine in a case study done in China 1.5 +- years ago. In that case study the EOD concept was abandoned. I saw the study as progressive and that caused me to do a trial of 2 g once a day. And continued for 6 +- months. I discontinued it with no noticeable adverse effects.
I have never had a test for homocysteine level although I asked one to be done. I would have acne like bumps that tended to reappear in the same place. With my increase in B12 these bumps only appeared with an increase in B12 and then for less than a day. They disappeared altogether.
I started another trial of 4 g per day spread over three doses which was the maximum based on the information I had. This was effective in reducing my ‘stuffy’ head which for short periods went away. This is a huge deal and I have been working on it including unclogging my Eustation Tubes.
I weigh 82 kg (82 X 250 mg = 20,500 mg = 20.5 g/day per above quote.)
I started a trial of 1.5 g 4 to 5 times a day for a total of 6 g to 7.5 g.
I continued this trial for 4 days. The first day I woke up in the night coughing up phlegm,and felt awful. I attributed it to having swum in a cold lake a bit too far. Since then I am still coughing up a bit of phlegm and my stuffy head and fluid in my eustachian tubes is gone!
My clogged eustachian tubes started about 5 years ago and I mistakenly thought it was swimmer's ear. I did get relief from treatment for swimmers ear until the end of the summer of 2020 and then ended up in the hospital in November 2020. I also had temperature regulation issues after swimming.
I started a trial of 3 g 4 to 5 times a day. For a total of 12 g to 15 g. My prognosis was rapid improvement and that is what happened. Guessing my reaction to the current trial could have been avoided at 20 mg per day.
I have just started a trial of 20 mg per day administered throughout the day.
I will likely have in a few days enough information and have
The results have to be taken in the context of the amounts and frequency I am taking and my current trial.
Using information from Overton with regards to B1 has been life changing. Pretty much it is easier to be me. I have plateaued and will be increasing my B1 intake in another trial.
I take the Betiane in powder mixed with water for economy and will be adding Methionine and Carnitine in a trial with powder in water.
I am ahead of this time last year with my swimming distance. I am at ¼ mile and expect to be at ½ mile earlier than last summer. I am ahead of my distance hiking and expect to be more ahead than the end of last summer. I still hike in the winter. It is a different dynamic.
I want to do some study and take Vitamin D and K2 for this winter. Have not decided what month to start. Going with sooner is better than later.
I again did a trial of Folate/L-Mehylfolate for three days at one mg per day. I have since started a trial of .5 mg every time I inject which is 5 times a day.
The last 30 days were hard as my body was experiencing healing with is tiring and I need more sleep and rest.
I did at times have the pain from my peripheral neuropathy return and had issues with no hunger. I was surprised as that had all but eliminated. Pretty much there was more healing available with more appropriate supplementation and there was no way I could know that. There is a difference from the agony of reversing out I experienced when under supplementing and the discomfort of healing with my appropriate/effective supplementation. Both are hard to deal with the first suffering needlessly caused by my belief that physicians would know how I should supplement to heal and they do not.
I can not express what a difference it has made since I supplemented adequately enough that I could evaluate any change in supplementation in 7 days. It has changed to know I know with in the first two days if not hours. I still wait until I evaluate other possible factors. 7 days so far has been the longest I have needed to make decisions. The effect is not always wonderful. I have the ability to ascertain that the change is positive thru experience. Allowing I may be wrong which I always do and give much more credibility to those who also work with the idea they may be wrong.
Reset - depleted
Wondering how weird healing can feel? 
