Current Trial (7 Days); 1.5mg methylcobalamin 3mg/ml, 1.5mg adenosylcobalamin 3mg/ml, 1mg hydroxocobalamin 1mg/ml. SC injection 5-6 times a day including setting an alarm to inject at night if warranted. 50 mg B6 in the form of P-5-P three times a day or pain from peripheral nephropathy returns. Benfotiamin B1 300 mg three times a day.
Administering B1 is a life changer for me. I have been working with B1 for about two weeks. I am/was B1 deficient.
Administering B6 was a life changer 3 +- years ago in that I no longer experienced the pain of peripheral nephropathy excepting when extremely experiencing low ambivalent temperature due to a power outage. I was a B6 deficient.
B12 has been helpful for me and a life changer over time. I did not experience the same effects that some share due to even 1mg 3 times a day to be insufficient supplementation of B12. I am different than some in that I experienced the debilitating reversing out that some do and need much higher amounts of B12 to heal although I was less worse with 1.5 mg B12 every day. I rejected after 3 +- years the advice that I would heal if I waited. That has been proved false.
I decided to preform a trial of B1 with B6 and B12 from my study of physicians who successfully treat peripheral nephropathy. At least some do prescribe B12 orally and call it good without the successful treatment.
I work with healing my neurological system and reject much of the applied science based on the work done 1/2 a century ago with the hematology model. I decided to do this rejection based on my evaluation of the work done with regards to treatment PA. Ground breaking 50+ years ago. Modified a bit by Chandy.
I have purchased Elliot Overton's work and will read his work and see if it adds anything to my understanding. He is a nutritionist and I will be aware of his likely prejudice. Trying as best I can to be aware of my prejudice.
Overton coined the phrase paradoxical effect of supplementation in that one supplements to feel better and feels worse for a while. I use this to get away from the acceptance of the severe reversing out caused by under supplementation of B12. Pretty much starving the body of B12 a little bit less and because some people heal with EOD everyone will eventually, pseudoscience which is still in vogue with many that advise on this forum.
I am as best I can as I improve my understanding and therefore self treatment the paradoxical effect of both eustress and emotional stress and with exercise. That is a rough row to hoe.
Keep an eye on "cofactors" is not helpful to me. I am working on how to administer
"cofactors". So far B6, B12, and B1 are best supplemented by doing trials as the current testing most commonly available are not sufficient to determine how to determine a deficiency.
I no longer treat for B12 deficiency and add cofactors rather I self treat my neurological system. B12 is just one way I treat my neurological system. I came to this from the understanding of the myoptic view of B12 deficiency based on that model works for some. B12 is a cofactor in my self treatment.
One advantage I may have is I am a licence soil scientist and wetland scientist and understand the difference between applied science and science. I even have personal knowledge of how some of the applied science came into being as I have worked with those that made up the applied science that is accepted currently. Plus I am not overly impressed with myself and how I apply science.
As an example the protective radius of a drilled well is anywhere from 125' to 50' depending on who writes the guidance. Science is 2' with a 100% safety factor.
B1/Thiamine dosing
