I'm a 31 y/o female. I woke up one morning back in April 2013 with achy hands and didn't understand why they felt so achy. I just lived with it until July. It wasn't horrible, just annoying, and it came and went--sometimes made worse by chopping veggies or cleaning--sometimes those activities were fine. In July 2013, I saw a rheumatologist and all my tests were negative. Then I saw another rheumatologist in Sept 2014. This time I had a positive ANA, Chromatin, and double stranded DNA. All the while my husband and I have been trying to conceive since Nov 2012 with no luck. I had a laparoscopy in Sept 2014 also to remove endometriosis--was under for 3 hours. Anyways, in the midst of seeing a rheumatologist we underwent IUI as well. My rheumy wanted me to start Plaquenil right away. I had the IUI done and started Plaquenil 3 days later. I started having dizzy spells and becoming anxious and weepy (thought I was pregnant, but I wasn't). Then 3 days later, I developed new symptoms. Both my elbows felt like they had rug burn on the bottom of them. This made me really stress out and emotional. Keeping them straight seemed to help, but I obviously couldn't do that all day long. Then I felt the burning in my elbow creases. But if I was busy and distracted sometimes they seemed better. Sometimes it reminded of my like having poison ivy on them. So after 6 days I stopped the generic Plaquenil (was only on 200 mg a day). It's been a week and a half and I still have my elbow issue and it's really making me sad and upset. I thought stopping the drug might help. I cry every day. It feels more in the skin than in the joint. My hands were never this bad. I don't know what to do. Could the Plaquenil have set off my elbow issue? The doctor says no because myositis would be more diffuse and not just to those areas. I thought about slowly trying name brand Plaquenil but I'm scared of side effects and what if it never helps my pain and it takes so long to work. The doctor gave me Voltaren gel to rub on my elbows, but do I have to do this forever?? Uhh… why is this happening? How can I fix this? I've even thought about trying LDN instead (when mentioned to my rheumy she said there weren't enough studies on it.) I've also cut out dairy and gluten. My hands have been really good, just my elbows now. Is this a flare or what? Will it last forever? I'm so lost and scared for all the what ifs. Any advice? Thank you!