Feeling defeated after IVF chemical pregnancy

[BabyWonder]

Really feeling bad as my IVF doctor did not practice APS treatment protocol for my 2nd IVF that resulted in chemical pregnancy at 6 weeks. The doctor only introduce baby aspirin despite the fact I was tested twice high reading (3 months interval) for APS. Now after discussion with the IVF doctor and mostly from our own research, my next IVF treatment will be 100mg baby aspirin, 40ml clexane, 200mg plaquenil, 10mg prednisolone. The doctor also want to introduce Intralipid. Though I think the doctor is willing to change protocol to help us succeed, I was pretty upset and traumatised when the clinic’s consultant said ‘the doctor will not be responsible for me because of the high medicine dosage. Not sure if I should continue with them but I still have 2 embryos left and so far the doctor is quite understanding. 😢

[MaryF Administrator]

Hello and welcome, I am so sorry to hear your sad news about your losses, where are you located? This information will help us to help you. If in the UK, we have a list of specialists under pinned posts over on the right hand side of this forum.

We also have a list of specialists across the world on our charity website: ghic.world/ It is vital that you work with a team who can not only support and help you but also your GP. A specialist who has the full knowledge of this disease within pregnancy and outside of it is crucial. Please stay on this forum to be supported by many who have been in your position, and then gone on to have a successful outcome. MaryF

[BabyWonder in reply to MaryF]

Thanks for the offer. I’m located in Malaysia. Unfortunately not much support for APS in Asia. It seems that most doctors are not familiar with this condition. We have seen private and public hospitals/clinic and have heard conflicting and different views - one doctor claim that I most likely will not benefit from any APS treatment for pregnancy/IVF as she said I don’t have any symptom though tested positive for APS twice. Very confusing.

[MaryF Administrator in reply to BabyWonder]

Here are medical papers out of Malaysia, maybe contacting the hospitals and the names on them: e-mjm.org/2012/v67n4/Antiph...

ncbi.nlm.nih.gov/pmc/articl...

MaryF

[BabyWonder in reply to MaryF]

Thanks for the info. Will look through and probably explore consulting another specialist in Singapore instead.

[MaryF Administrator in reply to BabyWonder]

Ok well you have the contacts above, and here is a paper written out of Singapore: onlinelibrary.wiley.com/doi...

MaryF

[Wittycjt]

Sorry you had to go through this, truly I am. 40ml? Are you sure s/he didnt mean 40mg? Please be sure!

[BabyWonder in reply to Wittycjt]

Oh yes, I meant 40mg clexane. Actually still deciding between 40mg to 60mg as worried that lower dose will not be effective. My IVF doctor said only one of his patient has used clexane so not able to give me much advice. In fact, the above treatment plan was derived from IVF doctor, gynae, Rhematologist and many research via website and me and DH come up with the treatment protocol plan.

[Wittycjt in reply to BabyWonder]

Specialist?

[BabyWonder in reply to Wittycjt]

Unfortunately I couldn’t find any specialist in Malaysia and for a private specialist in Singapore is about S$14,000 (£7900) just for blood test and medicine treatment for APS in relation to IVF/Pregnancy.

[Wittycjt in reply to BabyWonder]

Ouch!

[lianm8]

I used 40mg of clexane, 10mg prednisalone and had three rounds of intralipids for each pregnancy (just before transfer, 8 weeks and then 12 weeks) when going through IVF. When I had no treatment two rounds failed- I went privately and they prescribed the same treatment for both rounds and I have a little girl who is 19 months and I am 38 weeks pregnant with baby girl number 2. I wouldn’t have any treatment without it now x

[BabyWonder in reply to lianm8]

Thanks for letting me know. Really appreciate your reply and also having support and advice from this support group. For my Intralipid, my IVF doctor suggested 2 times only - 10 to 14 days before transfer and then upon BFP.

[lianm8 in reply to BabyWonder]

I suppose different clinics have different protocols- intralipids aren’t cheap here Either - i paid £350 each time. But I think it’s worth the money considering it’s only a fraction of the cost of IVF.

Wish you luck with all treatment x