Title says it all. How much of this heartbreak can a person take! It really leaves very little hope of this ever working.
Everything possible thrown at this transfer - PG tested embryos, increased progesterone, steroids and intralipids, clexane and aspirin, ERA, probiotics, acupuncture etc etc
I know I can’t give up but equally I don’t know how to keep going. Sorry for the negative post just looking for some hope on a dark day ❤️
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Patches86
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Oh Patches I am so sorry. It doesn't get any easier does it. Hope is a cruel thing sometimes.
I am not sure if this is what you need to hear right now but my sister got her BFPs on her 7th and 8th transfers with her last two embryos which were her worst and they are now healthy 3 yo and a 1yo. My friend had her baby on her 9th transfer.
Thanks Daisy, that does inspire some hope. I think it’s just so tough wondering whether that “might not be me” and whether it is a matter of eventually it will work or, the sadder thought, of maybe it never will!
I totally hear you. Its just the worst - the lack of control and the what ifs.. It took me a long time to realise it wasn't meant to be me with my own eggs, because there was always that story of hope that made me wonder if I should try one more time... the reality looking back was I never ever had something good enough to freeze - so why would it be good enough to make a baby!! I am optimistic for you though - you have age on your side and are making it to blasto regularly - I am ancient in comparison!! xx
I think with both of us, although different narratives (my issue being my body not allowing implantation and yours being a difficulty with your own eggs) we have the same outcome of no baby! And with both of us you right, there is always the story of hope which makes you wonder and a difficult decision as to “when” you need to take next steps (donor for you, surrogacy for me). PS you are not ancient!!
I don't have any success stories I'm afraid, but I just wanted to say I am so sorry to see this. It really is so hard when you feel like you are throwing everything at it and everything looks good yet no implantation, so frustrating 😔 you are definitely not alone in these feelings, although I know that is not much help.
I really hope you can find your winning formula 🤞 sending hugs to you on a difficult day 💐 x
Thank you. Yes I am going to have the ERA. It is more waiting, but I hope it gives me some useful information.
Did you think about LIT therapy at all? This has been suggested to me again during the follow up, trying to decide whether to proceed with it or not - it is expensive x
Hi just wanted to say I’m really sorry, must be so upsetting and frustrating. Hope you have some time to rest and switch off from everything before you decide what to do x
So sorry to hear this lovely, it's so difficult 😥 I'm in a similar spot. Have you maybe considered IVIG? It's on my list for my next time. Sending you hugs xx
Sorry to hear you’re in a similar spot - wouldn’t wish this on anyone! I know IVIG is super pricey and from what I understand is not anymore beneficial than steroids and Intralipid? Have you been told otherwise? Did you test high for NK cells?
I think for some ladies it can work a lot better. I believe that intralipids don't work for some, and the top reproductive immune specialists are still using IVIG.
I have some immune tests be abnormal including high ANA+ result and high TNFa, so seems like it could be the issue. I have IVIG and Humira on my list for next time and feeling hopeful about it. Maybe your dr can do more tests or explore whether they could throw these things at it? Best of luck lovely xx
Hi I’m sorry to read the sadness and disappointment. May I ask why you were prescribed intralipids and steroids? Have you had a second opinion on your situation? Sometimes another opinion could be all it needs moving forwards ?
My NK cells were borderline high and I think it was the last thing they could try after all my other failed transfers. I am going to get a second opinion although nervous that there isn’t anything left to do differently!
I hope you get some answers from another perspective. Does your clinic offer time lapse images on your embryo growth? It’s a highly regarded tool that works alongside grading in selecting the best embryo for transfer. I am not in the slightest suggesting it’s an embryo issue just covering all ground suggestions. Are your embryo transfers at blastocyst stage too? Have you had a hystersonigram test, to check for any abnormalities within the uterus that could be impeding implantation such as fibroids, polyps etc and is your lining at a good thickness at transfer? A minimum of 8mm ideally to give as good shot that the embryo can implant. wishing you all the best going forward. x
Looking at your previous posts did you see an endocrinologist? Have you thought about trying a gluten free diet- good for autoimmune thyroid conditions even if coeliac testing negative.
Through my own testing I was diagnosed with Hashimoto’s and went gluten-free even though coeliac testing negative. Endocrinologist didn’t suggest this but I thought it was worth a go. They did say to make sure thyroid function was stable before IVF.
Otherwise have you had internal checks eg hysteroscopy or laparoscopy?
I’ve got an appointment with an endo coming up in April. I’ll see what he says about gluten free diet although I have heard good things - thanks for sharing your experience too! I’ve done the internal checks and all fine so who knows what the missing piece of the puzzle is!
I am really sorry to read your latest post. This is really heartbreaking and it is going to take time to move forward. So take the time you need to grieve and process what has happened. Be extra kind to yourself and when you feel ready to do so, spend time doing things that will put a smile on your face - even if only for a short while. You are not alone in this journey so please take some comfort in that. Thinking of you today. Hopeful tomorrow won’t be as dark a day x
This is such shit news, I'm really sorry. 💔 Sending you a huge hug.
This is probably a silly question because you've obviously had the full gamut of tests, but have you had your vitamin D levels checked recently? Low vitamin D is linked to implantation failure and seeing as how we're just coming out of winter, it's not uncommon to be deficient unless you've been supplementing regularly.
Also, this is a slightly weird one but have you ever had your iron levels checked? My gp did an iron panel after my second chemical and much to my surprise my levels came back borderline low. Ever since increasing my iron intake with a supplement, my anxiety has been WAY better and I'm just feeling much more myself overall. There don't seem to be any studies specifically linking iron deficiency to implantation failure, but it seems logical that if your blood doesn't have enough oxygen then that could be negatively affecting fertility. But frankly, I feel so much better overall now that I've upped my iron that I kind of don't care whether or not it's helpful for fertility! Just something to consider.
For today, I hope you give yourself a big hug and can be especially gentle with yourself. You've been through a lot xxx
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