Im 65 years old. Anybody do Chemo for prostate cancer after going through 16+ years of various treatments? Surgery Feb 2002 came back a year later, Lupron + casodex failed 2 years later, Meyers protocol Leukine + Ketoconozale + Estrogen patches worked for a very long time, Zytiga did not work, Radiation followed by Provenge gave me a PSA of less than 0.02 and a long remission, XGEVA is ongoing for bone health and osteoporosis, XTANDI slowed it down for a while, Radium 223 slowed it down recently but as soon as I finished all 6 infusions, it started running amuck again with bone involvements. All my previous therapies have had minimal side effects and/or managed with other meds such as Lipitor for high cholesterol, aspirin to thin blood, etc. Oncologists said I am ineligible for clinical trials because I had "too many therapies". Chemo soon and I am going to hate the side effects.