Experiences with

Provenge

After having lymph nodes and right lung metastasis test negative for lung cancer and providing radiation, I am now being prepared for Provenge treatment. I still have upcoming radiation for a spinal lesion and left iliac lesion. Anyone with Provenge suggestions/thoughts? Thank you!

To my brothers, today I start my first of the three Provenge cycles over the next four weeks: collection/infusion. Any tips from those who have been there, done that? Thanks!

I have some other thoughts about Provenge usage in general, but I'll put them in a separate post.

any study/trial done to show Provenge and Docetaxel can be done concurrently ? Tall_Allenany clinical trial to prove that Docetaxel cat be started along with Provenge. My dad’s PSA is increasing - doubling time is one month (4 weeks).

In my researching into Provenge (both the treatment itself and where to receive it), and in reviewing posts on PCa forums (perhaps mostly other forums besides this one), I've noticed some interesting patterns. Provenge was approved around 2010 and had a troubled opening.

Anybody that has TMB low and had a good run with Provenge, please, please let me know. Thank you so much.

My first PSA reading after finishing Provenge on 9/23 was 2.72 on 10/2. The last PSA reading just before Provenge began was 1.88 on 9/5. It had been at that level since around June 1 over four readings. Any possibility that Provenge can cause a rise (temporary or otherwise) in PSA?

We decided to do Provenge and after that SBRT to the Mets with Dr Kishan at UCLA.

Is this the actual cost of provenge? It seems to me that the costs are rocket high especially for non American patients? I'll appreciate to hear some comments. Thank you.

Had my first leukapheresis done Friday, then had my first re-infusion with Provenge yesterday. So far so good. No side effects yet.

PSA 0.1 since 02/2018 only treatment so far is Eligard every six months Zytiga Prednisone and Provenge back in 2019 . While my quality of life has changed significantly the key word here is life.

He finished Provenge 2 months ago. Recently he started experiencing extremely tiredness, he is walking very slowly and can’t do many of the activities he used to. I never seen my dad crying before but now he tears many days telling me that he doesn’t feel well and can’t do anything.

I had the third and last re-infusion on Monday. My port is being removed today. I'm part of a clinical trial, and if I'm in the arm that gets a 4th dose (the other arm gets no additional treatments), that will happen in 20 weeks. The only side effects worth noting happened after my second re-infusion

I checked online a day or so ago and found that Medicare seems to have covered my Provenge. $58K billed, Medicare approved $55K, paid $44K, leaving 11K for my United Health supplement to cover.

For the last five years I’ve been on and off of, Provenge, Pluvicto, SBRT, first and second generation ADT and currently BAT. I recently contracted a serious blood infection for no apparent reason only speculation by doctors that it was a UTI that jumped into my bloodstream through my kidneys.

What about Provenge, which the article doesnt address? Does Provenge also induce senescence? How do you chose and optimal strategy. Would appreciate your views.

Pluvicto (if even possible to get)...provenge?

From hormone shots Zytiga to Xtandi, to radiation, provenge two clinical trials, docetaxell, and now Pluvicto that I don’t believe is doing what it needs to do. I’ll prepare myself for the next chemo.

Did three treatments of Provenge and started on Lynparza/abiraterone which slowed progression for a few months into mid 2024. Then switched to Talzanna and xtandi which only slowed progression a bit. At this time my PSA is around 6 and it is November 2024.

Lots of frustration with failed treatments, as follows: Three sessions (infusions) of Provenge did not have any real impact, except psma numbers continued to double. Xtandi was started in September and PSA numbers began to triple and by December were over 300. Lower back pain developing.