Hi all,
Going to give this another go. Hoping it makes more sense than my last post.
Here are my blood results and the medication I was on during each test:
Bloods on 50mcg of Tirosint:
TSH 1.87 mIU/L
T4 17.7 pmol
T3 3.9 pmol
Bloods on 75mcg of Tirosint:
TSH 1.06 mIU/L
T4 17.5 pmol
T3 4.4 pmol
Bloods after 5 weeks of NDT:
TSH 3.12 mIU/L
T4 13.6
T3 5.3 pmol
I initially tried 50 mcg Tirosint which I responded well to and was then put on 70mcg of Tirosint and it was an absolute nightmare I became really mean and my PMDD was the worst it had been in a long time. I then dropped back to 50mcg of Tirosint and felt as close to normal as I had in a while, I wasn't constipated and felt relatively good but the following nagging issues were still present:
- Muscle fatigue specifically my arms before my period
- Severe PMDD 2 days leading up to period
- Cold feet and hands but my body temperature regulation was definitely better
In an attempt to get rid of the above my Endo recommend I try NDT grain 1 and said I can go back to the Tirosint if I don't like the NDT.
Now I've been on NDT grain 1 for 6 weeks and I definitely feel more motivated and alive but the following issues are still here:
- Muscle fatigue specifically my arms more frequent but not as intense
- Constipated (I was not constipated on the Tirosint
- Over heating (I feel like a heater constantly. I'm so warm my body feels itchy).
- A lot of my hair falling out daily
- My partner reckons I've been more obsessive (anxious) and I agree
- Insane increase in appetite
- Fingers and toes are still cold but it looks like circulation has improved in my feet as they no longer turn purple.
I saw my Endo yesterday and he suggested I try taking an extra 1/4 grain of NDT every second day to see if it resolves everything as my numbers are looking good but there's room to increase the T4 and it's clear some things are better. He said I don't have to if I don't want to and to be really cautious with the increase which has made me even more unsure of increasing the dose. The other option is that I have Grain 1 NDT with 25 mcg compounded Levi-thyroxine.
Now here's the thing even with the improved mood etc., the side effects of the NDT just feel like a deal breaker to me but it's also only been 6 weeks and I had my 2 year old niece here for over a week so I didn't really get to monitor my symptoms leading up to my period and I'm currently beyond exhausted after looking after her.
So I'm thinking of sticking to taking grain 1 for another 4 weeks and actively monitoring and writing down how I feel and any symptoms I have and then seeing if I want to increase my NDT.
If I still feel like NDT is not it I might just switch back to my Tirosint for 6-8 weeks and see how I feel on it and then go see my Endo once I've done some experimenting on my own.
My current gut feeling is that I'll be better off on Tirosint and Cytomel as I'll be able to tweak and find the right dose of T3 for my body where I can't really do that with the NDT. I'm skeptical of upping the NDT as my appetite increase has been insane and I'm sick of feeling like a heater.
All of my other vitals (Vitamin B, Vitamin D, Ferritin etc.) are in good standing.
I guess what I'm asking is what advice do you have for this situation? My gut is telling me the NDT is not it even with the few improvements it feels as if the Tirosint was just a better fit.
Do I give the NDT another 6 weeks to see if the symptoms I'm currently having resolve, try an increased dose, try the compounded Levo-thyroxine, or do I go back to my Endo and make a case to shift back to Tirosint and trial taking Cytomel with it?
I'm not sure how much longer my insurance will pay for appointments so I need to do the most with the time I currently have. I will pay to see my Endo but it's not cheap so trying to make the most of it.
Thank you for taking time to read this.