bit of back story, I have been on 1 grain of NDT for 3.5 years (with added t4). Every time I upped 1/4 grain I would get hyper symptoms and it would push my t3 over range. So I had no choice but to add levo in (tirosint). T4 seems to make me feel worse and worse the higher I go in doses with extreme fatigue.
I have been working on my low iron and low cortisol recently and decided to up the NDT for the 6th time in 3 years and I am finally tolerating 1 1/4 grains (2 weeks in). Usually I have to pull myself off after a week because I feel so bad.
My main current hypo symptoms are extreme fatigue, muscle aches and weakness, hair loss, weight gain etc. I actually feel no better from the increase but not worse.
My question is do I need to wait 6 weeks after bloods to up another 1/4 grain or could I try and attempt it in a week or so? The fatigue is so excessive I am unable to work, struggling to wake up, having vivid really deep sleeps. I also have PoTs and orthostatic hypertension & ME (although I still swear the ME symptoms are my thyroid). Obviously my pots etc is really bad at the moment due to the awful fatigue my body’s struggling to stand or move.
Current doses
t4: 4 days 75mcg, 3 days 100mcg
NDT 1 1/4 grain
Written by
Ajva
To view profiles and participate in discussions please or .
It might be that the Thorne dose isn’t enough, are you following any particular advice re. Thorne, like Peatfield or STTM or are you just taking 1 tab of 50mg in the AM?
I am on taking the 50mcg. My cortisol is still really low so I am hoping by upping my t3 slightly it will start to pick up. I am having cortisol tested again next week so I will see where I am at. Any advice how to up cortisol would be appreciated
from what I’ve seen here and my own experience, it takes quite a long time to tolerate a dose uplift of NDT. I take mine in one dose in the morning at least 1/2 hour before food with a glass of water. You may find it easier to split the extra (I take 1 grain in morning then 1/4 4 hours later. Then stick for at least 6 weeks at that level. I don’t (yet) balance it with Levo though. It may be a conversion issue from Levo but others will be able to comment about that. Don’t hurry the NDT - let it take its time.
you are right, I think after attempting to dose increase 6 times and finally being successful this time round I was probably getting excited and a bit ahead of myself. The only reason I would like to increase after 3/4 weeks is due to the debilitating fatigue I have, which is causing me to spend my days house bound and laying down at every opportunity (when I haven’t got my little one to look after). The holidays have been dreadful for me with how I have felt. Thank you for your advice
Have posted most recent ones on a previous post but will try and add to this comment. I think my t4 has been slowly decreasing over a space of 4/5 months which hopefully explains my symptoms. I feel better when my t4 is much higher more near top of range. So I think I may need quite a few increases
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Help ndt dosing!
Is this a "normal" reaction to NDT? 
Starting NDT - combining with Levo ?
