Any thoughts on vitamin levels?: Thanks to those... - Thyroid UK

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Any thoughts on vitamin levels?

Megaloo profile image
11 Replies

Thanks to those who suggested I check my vitamins after my earlier post.

The below results are from medichecks. In their doctor's feedback they suggest I take a Serum MMA test due to low b12. Do you think they are right? or can I try supplementing and if that works assume I don't need to? Any thoughts on the others do I need to supplement them all? For those that don't seem to have a top end of range (Folate and B12 I think), what would be a good number?

Ferritin 129 (30-332)

Folate serum 8.2 (>7)

B12 active 50.7 (>37.5)

Vit D 69.6 (50-250)

and below looks much same as before unsurprisingly as was only a week or so apart (it was still the cheapest way to check the vits)

TSH 0.045 (0.27-4.2) - was 0.02

T4 17.9 (12-22) - was 17.1

T3 4.4 (3.1-6.8) - was 3.4

Thanks again for any feedback

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Megaloo
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SlowDragon profile image
SlowDragonAdministrator

Folate serum 8.2 (>7)

B12 active 50.7 (>37.5)

Vit D 69.6 (50-250)

These are all too low

Low B vitamins

Are you vegetarian or vegan?

Just add supplements and retest in 3-4 months

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

In-depth article on different forms of B12

perniciousanemia.org/b12/fo...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

perniciousanemia.org/b12/le...

And why aiming to keep B12 over 500 recommended

perniciousanemia.org/b12/le...

Great reply by @humanbean on B12 here

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and may need separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

SlowDragon profile image
SlowDragonAdministrator

how much vitamin D have you been taking

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Can test via NHS private testing service

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Recipe ideas

bbc.co.uk/food/articles/mag...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

Megaloo profile image
Megaloo in reply toSlowDragon

Thanks so much SlowDragon - I will read through and get my act together. Really appreciated. I don't take any supplements at all (doc did prescribe vitamin D a few years ago but stopped). I'm not vegetarian or vegan.

So you don't think I need to splash out on this Serum MMA test? 🤞

thanks again

SlowDragon profile image
SlowDragonAdministrator in reply toMegaloo

So you don't think I need to splash out on this Serum MMA test?

No ….you’re on Levo. Low vitamin levels are virtually guaranteed unless supplement

Megaloo profile image
Megaloo in reply toSlowDragon

brilliant, thanks!

Blue_Lagoon profile image
Blue_Lagoon in reply toMegaloo

Hi Megaloo,

A quick google came up with this website (sorry I don’t know how to put links in properly!)

pernicious-anaemia-society....

The bits I took from it were that you shouldn’t supplement before having the MMA test. Treating with B12 will lower your MMA value.

As your B12 is in range the MMA test could be useful as it highlights if your symptoms are actually due to B12 deficiency despite a normal serum level of B12.

I would get the test done. I think it’s something you could show to your GP if it indicates that your symptoms are due to B12 deficiency and if it turns out that you are incapable of absorbing B12 in the gut from tablets, you may need B12 injections which your GP can prescribe. Would be useful to show to your GP.

Hope this helps.x

samaja profile image
samaja

I would not just take B vitamins if your diet is good but ask the question first why are your levels so low? Have you got any known absorption problems? If so, taking B12 in anything will only mask the problem by raising the blood levels but not actually addressing the deficiency itself at the cellular level becuase the only guaranteed way of working on B12 deficiency when you eat meat, dairy, eggs and fish is by having regular B12 injections. Anything oral is only suitable when you are a vegan/vegetarian.

I would take MMA test if it was suggested and also aks for parietal cells and intrinsic factor antibodies tests.

Jaydee1507 profile image
Jaydee1507Administrator in reply tosamaja

Poor vitamin absorption is part and parcel of being hypo. Many people do well with OTC oral supplements.

samaja profile image
samaja in reply toJaydee1507

WIth all due respect but it's not the case for everone. I have excellent absorption despite 10 years of Hashimoto's most of which I was hypo due to not tolerating levo and have good vitamin levels with no supplements. Yes I had gut problems to start with but worked on at and addressed low vitamins on the way and for many years they have been fine. My vit B12 was never that low though. However, I don't think making this kind of a sweeping statement is really helpful, just in case someone has more acute B12 deficiency such as Pernicious Anaemia which can be far too serious to have the diagnosis delayed just becuase the right questions have never been asked and supplements taken which might work for a while before the big crash follows.

Megaloo profile image
Megaloo

thanks to all who've contributed to the above discussion - I'm very tempted to not do the MMA test (£149 at medichecks, can't seem to find it any cheaper), but having spent decades undiagnosed with coeliac (before finally being diagnosed) I'm a bit wary of possibly covering up another autoimmune etc. I shall mull. But really useful (both points of view) - thank you.

Megaloo profile image
Megaloo

PS if anyone knows anywhere cheaper for MMA that would be helpful in making decision

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