endometriosis together with hashimoto. #Peri or menopause#

[Marinaaa]

Hi everyone! I would appreciate some advice, I am going to mix a few things here but if someone feels related please answer to me.

Last visit to my gine in december she said I am nearly menopausal and my endo suggested starting bioidentical hormones because he believed my hormones were low and has been saying that for months and being 45 he adviced so because he believed it could help a lot and I found about bioidentical hormones and they required a vaginal ultrasound/scan and several test before considering it.

So I have been taking tests to understand where I am. However in these last months I spend 86 days without a period, then two consecutive 25-27 days- period with ovulation where I took the tests and now my last period has lasted 14days And I am also having some night sweats and constant cold sweats day and night since some months ago. I can cope with it however. Annoying if some days it wakes me up. Very tired and I decided to take daily isoflavones for three months, and vitex as adviced by gine who said it was a stupid idea to start on hormones.

Still on vitex but given up the isoflavones. My aim with vitex was treating my extreme sadness and tiredness during the period and force perhaps ovulation.

Wel so I did this scan somewhere else and I was found an endometrioma of 30per 24mm, the gyne said it is small and nothing to be done about it but the radiologist has asked it to be revised in three months and has ordered tumoral markers.

Not given any medication or advice by the gine. She said she was checking tyroid which was related and ordered just TSH and T4, so I doubt she is going to help much, and with a supressed TSH and osteoporosis dignosis she is going to panic.

I feel angry, I find they could have helped me earlier, years ago. 10 years ago I was told I had a quist which later was told it had dissappered but nobody mentioned endometriosis at all. I have had really bad stomach pain for 15 years, but that was specially when I was on monotherapy with plenty of different sympthoms, including night sweats at 35 years old.... since being well treated for thyroid I get stomachaches every once in a while. However I have a huge belly, I have always had it, and feel sometimes bloated. Since learning about the endometrioma, I feel more pain on that side and vaginal left side pain is back again. I had attributed everything to the very slow recovery I have had from hip surgery but now I have doubts. I felt a huge improvement since starting on T3 and now I am starting to panic if old sympthoms are coming back.

I would appreciate some help from someone who has endometriosis as well. I also have osteoporosis so this adds to a list of illnesses and it is somehow of a new burden when I am still trying hard to recover my general health due to my hip problems. But I think they are kind of separate things, the hip problem and this endometriosis issue, I dont know.

I´ll be visiting a private gine in some weeks to get a second opinion on the hormonal issues. Then apparently I´ll be getting vaginal scans every 3months as the procedure. However no mention to how to cope with it.My gine says with every test she sees Ï´m on ovarian failure but then in every scan I have folicules or have ovulated.

I am feeling a bit down and I think I might need to increase my lio meds a bit and would need some advice on how to do it. I wont see my endo until two months and he adviced to do it if FT3 went down sometime. I am currently taking 88levo plus 25 lio. Should I decrease to 75 levo and add 6extra lio? I wonder if FT4 wil go down excessively. Thanks.

Well, these are my most recent labs: APRIL 2024

DAY 3 FSH 34.57 UI/l (previous labs FSH was 40(sept), 30(july) and 75(december 2023)

ESTRADIOL 25,3pg/mL

PROGESTERONE 0,45 ng/mL

TESTOSTERONE TOTAL 0,09 ng/mL

FREE TESTOSTERONE 0,57pg/mL

TSH 0,01

FT4 1.16 ng/dL (range 0.92- 1.68)

F T3 3.07 pg/mL (range 2-4.4)

7days after ovulation:

ESTRADIOL 73 pg/mL

PROGESTERONE 10.3 ng/mL

TESTOSTERONE TOTAL 0,14ng/mL

TESTOSTERONE FREE 1.12 pg/ml

Previous labs NOVEMBER 2023

TSH 0.02

T4L 1.01 ng/dL (range 0.92- 1.68)

T3 1.43

FT3 3.62 pg/mL (range 2-4.4)

Thanks for your priceless help.

[WeeB]

Hi Marinaa , I can’t say for sure but a lot of your symptoms defo sound menopausal rather than thyroid . And your bloods defo show peri and on the way to meno or already menopause . Maybe ask for a second opinion from another gynaecologist to see if all hrt types are off the table ( including estrogen patches , testosterone and utrogeston ) . Or if you can afford it , speak to menopause specialist who also understands and is experienced with your health condition( don’t know if a specialist like that exists in uk though ) Failing that , i think there is new non hormonal medicines coming out or already out in uk that treat hot and cold flashes , you could ask your doctors about that but may just be in US just now. Sorry i’m not much help , just don’t know enough about endo except that certain hormones can cause it to grow. Some supplements might help with your symptoms too but would need to check with gine as some of the menopause supplements have stuff in that encourage estrogen production or are forms of estrogen . Sorry your going through this . Hope you get somewhere with it soon .

[WeeB in reply to WeeB]

oh and apparently i heard from some people that when your heading to full menopause , your body can do weird things with ovulation and long bleeding as one last harrra before it goes completely

[Marinaaa in reply to WeeB]

Thanks WeeB yes I have to find a good specialist. Its always like that, isnt it? Probably my thyroid is working less well as a result of very low progesterone on months when I¨m not ovulating, it could be that as well. Its all a mess I know, Apparently endo is triggerd by excess estrogen but also by the inmune system. I paid for a celiac analyisis even if Ihave been on and off gluten for years to see if I get this information clear.

[WeeB in reply to Marinaaa]

if endo is made worse by estrogen then hrt patch will probably do it too as has estrogen in it. but again need to check with a specialist .

[Marinaaa in reply to WeeB]

Thanks WeeB, actually I¨m visiting a gine who I know works with endometriosis and I will ask her about the hormones as well. I suppose if I end up taking them it will have to be very supervised with the quist but hey, I had a quist 10 years ago and then it went away when I was in my thirties, so if I´m careful and supervise it, why not trying now?

However my current gine (before knowing about the ndometrioma) she said she would only give me hormones after 12 months without a period because she could be causing me a cancer, so I guess she doesnt go for sympthoms.

I dont know if this treatment is included in the national service (pathces and so on) because my new gine is going to be private.

[WeeB in reply to Marinaaa]

i started the evorel hrt patches and utrogestan at 43 with my gp but i think if your private doctor recommends it , they can write a letter for you to your gp and hopefully they will prescribe it if you want it on nhs.

[WeeB in reply to WeeB]

oh sorry didn’t realise you might not be in uk

[Marinaaa in reply to WeeB]

I´ll try that. I read that it was included for early menopause, but being already 45 they may say it´s not early. I have two friends my age who are already menopausal and they havent been given anything, I would say they tend not to recommend it anymore. In the past everyone got it prescribed.

When you started patches, were you still menstruating?

[WeeB in reply to Marinaaa]

Perimenopause can start for many people well before 40 and carry on to around 51. think average age of full blown menopause is around 51 but everyone is different . i still have regular periods , im 45. my sister started hrt when her periods were random , heavy but every 3 or 4 months . there is no real age for starting , it’s just about when your symptoms kick off and there is no longer a set time to come off hrt for most people , some d stay on it their full lives for health benefits . there is a lot of misinformation out there and old research based on old type hrt . the new style hrt is much less risk . Maybe check out people like dr louise newson or dr mary claire haver or dr naomi potter on line or instagram and the balance app for more info , they all have books too . A lot more people are starting hrt in their 40s in the uk now thanks to new updated info and the newer hrt. But expert advice might be needed if you have health conditions that feed off your hormones. because adding more could affect it . xxx

[Marinaaa in reply to WeeB]

Thanks, I´ll have a look at all the information. By the newer hrt, do you mean the biodentical pellets or implants? My endo advised on that but now that I have learnt about the endo thing I wonder it might be dangerous, sth shorter term life maybe better. I´m a bit confussed on whether I¨m menopausal or perimenopausal. Gine said she couldnt declare me menopausal until 12 months without a period.

[WeeB in reply to Marinaaa]

So not bioidentical ( i believe that is still very new and not researched enough yet ) . i was talking about body balance-menopause.com/menop...

Your classes as menopausal when got a not had a period for 12 months . for a lot of women , the fluctuating perimenopause stage is the worst for symptoms due to the constant rise and fall of the hormones , and that can last for 5-10 years roughly . either way , your hormones are reducing.

You’ll get tonnes of answers on that website above or you can download the app . it has a handy cycle / sympton tracker too .

[WeeB in reply to Marinaaa]

just want to remind you this is what i’ve learned on my menopause journey and my own interpretation of the info , and i’m still learning , so best to read the experts online and take your doctors info and decide what suits you best once you have all the info . I see people talk about bioidentical online but i don’t know much about it and nhs don’t recommend it or prescribe it as far as i’m aware . who knows what will be the best hrt in 10 years time though , still so much more research to be done for female hormones . Good luck , hope you can reduce your symptoms soon , one way of another xx

[Marinaaa in reply to WeeB]

Hi I´m back from my gine, I asked for another appointment as my period had lasted for 15 days and she has performed another ecography, and my quist has reduced from 3cm to 2cm which is great. In only a couple of weeks. I was so scared I was going to end up in surgery with all the hormones ups and down..... I have been super careful with what I eat and taking a few supplements I know, so I¨ll go that path.

Well the thing is that I have asked her again about the HTR for insomnia and sweats and because I feel supertired and angry well sometimes, and she has told me that my age is normal, everyone has sympthoms in menopause and that is no reason to take anything because my age is normal.

She has said that the only thing she could give me was contraceptive pills which contain natural estrogen and progesterone and she has prescribed me Zoely. She says that until 12 months without a period have passed, patches cannot be given but that anyway she was against HRT. I have told her that I have osteoporosis and would like to recover my physical health and then she has said that with contraceptive pills I could go on for a few years no problem.

It is true that for endometriosis contraceptive pills are indicated as they keep the ovary quiet and the endometrium, but if I could handle the endometriosis with natural therapies, maybe the other route of estrogens, patches etc is safer. My blood circulation isnt great, they always say for my age my legs arent very good, some venous insuficiency.

I have an appointment with a very good gine in two weeks and I will discuss everything with her. However, Im not sure if they work with patches for premenopause in my country.... I know this gine I´m visiting does pellets, and she is also an expert in endometriosis (conferences and a book written) so I hope she is ethical and doesnt try to sell me the pellets. Always in her books and conferences she says that menopause is a natural thing, no need to medicate it, but that every patient decides her path.

I dont know Im getting so nervous with all these visits to doctors. Perhaps I should go to the reumathologist and see what pills are better for bones. contraceptive have a one release, pellets release constant estrogen. I have been avoiding that visit since I got the diagnosis three years ago because they mess everything, and my trauma and my endo said they would do nothing until my hip is recovered and I can walk fast and do exercise again. So I agreed. Besides he will say I am hyperthyroid for sure with my low TSh so.

what are your thoughts? im so new to all this. I have to investigate, is difficult isnt it having to investigate by yourself everything. We must have already studied a couple of years of Medicine.

[WeeB in reply to Marinaaa]

Hi Marina, You have so much going on medically , i couldn’t really give you my opinion on this except to suggest asking the endometriosis society and maybe read some books for more info on current research and menopause information . I really like the definitive guide to menopause by Dr Louise Newson in the UK . Although there isn’t much about endometriosis in the book so seek specialist help for that . One thing i would say is i agree menopause is a natural process, i think everyone knows that it’s natural , but i don’t think it’s a justification for not fully informing people on up to date current research and available hrt or alternative options including pros and cons and current research health risks etc so they can make an informed choice about what is right for them and their current and future health . just because something is a natural process doesn’t mean everyone is affected the same and doesn’t mean people should suffer when there may be options out there to make that process a bit easier . Fingers crossed for your next gine appointment that you get a more detailed discussion .

[Marinaaa in reply to WeeB]

yes, thanks. I´ll have a look at all the info that you have shared. Thanks a lot

[WeeB in reply to Marinaaa]

i’ve never heard of zoely sorry

[Marinaaa in reply to WeeB]

it has estradiol plus a progestin. Also called miranda, I think.

[WeeB in reply to Marinaaa]

is it transdermal?

[Marinaaa in reply to WeeB]

no no, it is a contraceptive pill. I have told her that patches were safer but she has said no, and also cannot be used until 12 months without the period. It is true however that contraceptives are used to stop endometriosis from advancing, I have read.

But if I manage to stop it somehow differently I may not need them.

[Marinaaa in reply to WeeB]

Zoely nomegestrol acetate 2.5mg / Estradiol 1.5mg

you take them three weeks out of four, like contraception

[CoeliacMum1]

Hi

I very much sympathise with you on this, I’m experiencing this regarding gynaecological issues.

I have Adenomyosis with Endometriosis recently found at last September/October at age of 57… I’m 58 next month still perimenopausal. I also have Hashimoto’s, Coeliac disease and Pernicious anemia they are all related and common to unfortunately have more likelihood of gynaecological problems …I’ve had a Dexa scan for osteoporosis decade ago but I was deemed ok… and I’m going to ask for another… coeliac disease runs a bigger risk of osteoporosis and I did have family member with it.

I see you’re in Spain I can only let you know my experience and what I know NHS will possibly do and had Privately, mines been a mix of both.

Here in U.K. and I am pretty sure it’s done similarly elsewhere, but can’t be sure… testing of sex hormones are hit and miss after 45 sometimes earlier in some people… our hormones are very much up and down over 24hrs in perimenopause so it can show one thing one time and not at others… here they predominantly go on symptoms to prescribe HRT… given are combined and oestrogen only patches or oestrogen sprays and gels & utrogestan (oral progesterone) these are safest options, mirena coil is a prosgestin (as synthetic hormones slight more risk in terms of safety of use but it’s negligible) I was told this is very effective for adenomyosis and I had this fitted in October it’s very localised hence it’s benefits.

This area is very complicated as little is known of causation… it’s seems in some it’s balance of hormones that a trigger others its immune response it’s possibly mix of both there’s unfortunately no cure but to manage the condition, it’s thought it’s spread by lymphatic system as endometriosis is found elsewhere not just reproductive organs … operations to remove adhesions to varying hormone control and obviously pain relief.

As you already have osteoporosis I would make sure you are aware there’s hormonal treatment Decapetyl injections (I’m on it and why I want another Dexa scan) that can cause osteoporosis if on it long term.

I have always had mid cycle bleeds pain at ovulation since having my daughter 30yrs ago nearly, but generally ok until 49/50 yrs old it started with lower back pain, sacroiliac area, hip and thigh pain, I have been on hrt in varying doses and having abnormal bleeding on hrt and my age presents a warning… twice been through the 2week wait pathway for gynaecological cancer luckily not cancer but hormonal cyst and adenomyosis was found at my first scan my 2nd lining thickness was more but still not too bad but as this is reoccurring I was then put down for biopsy- Hysteroscopy I had this privately under general anaesthetic biopsy done 2 polyps removed and D&C and coil fitted.

What I’ve researched is both endometriosis, adenomyosis and thyroid do better with progesterone balanced and cortisol/stress depletes this area… it causes an imbalance and you end up oestrogen dominant not good for thyroid or gynaecological conditions… this might not be your trigger but in relation to what read Thyroid struggles with too much oestrogen and it possibly block conversion of T4-T3 but there are other nuances that can cause conversion problems.

I tried Liothyronine for a year initially was better but still struggled with low FT3 it seems my hormones just blocked it… I am having my annual review next month and interested to see now hormones are being shut down if it’s had any impact on this … I am on 3 injections in though.

Regarding your hip my right hip is a problem and endometriosis was found via a pelvic MRI in my pelvic cavity and on bowels if the endometriosis adheres to sciatic or other ligaments or nerves this can give you referred pain elsewhere… it’s very difficult to know… I would visit Dr Louise Newsons Balsnce website for everything Pre,peri and post menopausal. Look to read more about the condition endometriosis and that unexplained problems could quite possibly be linked… thyroid if you have a thyroid condition may be altered throughout this situation but on reading your gynaecological conditions probably need looking at first… your symptoms you share sound more perimenopausal but I don’t know what they’ll do as I’ve had to come off HRT and have injections as we think I have too much oestrogen and is causing my symptoms of endometriosis flares .. this is for 6 months I will be back on hrt I think if my condition improves it may just be the transition to peri to post menopause for me I’m hoping anyway… I’ve had a decade of incapacity I don’t drive anymore virtually stay at home as I can be doubled up in pain… I have a tummy that looks 6 months pregnant rarely does it go down it’s not just excessive weight.

I do wish you a quick diagnosis and recovery.

[Marinaaa in reply to CoeliacMum1]

Thanks very much for your answer. I appreciate all your advice and hope you will come soon to better solutions.

i have read that endo probably disappears with menopause. Perhaps you would feel better or can you find a very low dose of estrogen maybe that doesnt cause so many flares? Heard that DIM also lowers receptors, and a few other plants.

Just would like to say I believe I eased sympthoms in the past following a strict and boring anti-inflamatory diet, with brown rice, sarracen wheat, quinoa etc as grains, lots of vegetble fruits fish and meat, well i have some books about it, and then there are some supplements as NAC, glutamine, curcumine, resveratrol, vit C, omega 3 and many others, taurine... which help with antioxidants for the body and I believe this natural path is quite possitive. I have found after reading books (spanish) this supplement NUTRIDION COMPLEX which I might try. So far I´m with the NAC which was also advised for recovering thyroid health by Alexander Haskell whose book I read years ago.

For instance, after my first hip surgery I developed an adhesive capsulitis (apparently sth very rare which was attributed to the inexperience of the doctor which harmed the capsule too much) butI was eating normal at that time and with plenty of sugar. For the second surgery I was doing this anti inflamatory diet as adviced by physiotherapist and because I was very afraid of my sudden incapacity, and that surgery went really well, I got no adherences at all and even scars are looking better.

Anyway, I believe my current hip problems are not related to the endometriosis and I really hope so. After some very unprofesional physiotherapeutical manieuvres I lost the biomecanic of the pelvis and my whole body after and that has led to several years of strong incapacity but I was better before and I¨m a sportsperson and slowly listening to my body and with all the knowledge of physiotherapy I have gathered my biomecanics is improving to normal and hoping to recovercompletely. I too have some of the pains you mention. But thats what I hope for at least for now.

Regarding next steps I dont think my gines are going to do much, she already said it was too small the endometrioma and hasnt shown much interest in sympthoms and when I mentioned stomachaches for years she said there was no relationship.

Perhaps they are just waitng for the endometrioma to grow and then take me to surgery. I will visit a private gine in Madrid and see if she is more helpful, and at least I can discuss openly about HRT cause I believe in this country it is considered harmful and not recommended. I Have two friends already menopausal at 46 and they havent been informed about hRT.

At least I Hope she will give me progesterone. i think this month I havent ovulated either and I feel so tired I wouldnt wake up of bed or sofa all day long. Could be depression but as it doesnt happen all the time I bet is the low hormones rather.

Do you really think hormonal values change in a day? I have made a few test and they alwasys show simlar values, around 20-25 for estradiol the first days of the month, and when theres ovulation ( i go and do the test whenever I´ve checked there has been so) at around 65-70. SAme for the other hormones, like I´m pretty stable. I dont know. I feel like I might have to go around and visit a few doctors to find solutions. I hate that.

Regarding the medication you say is ostoeoporotic, I took it when I froze eggs, they did three rounds for me, can that have caused osteoporosis? I read endo in itself caused osteoporosis because of the inflamatory cytoquines, and my endo said to me it could have also been medications I took in my twenties for hay fever. Who knows, Im afraid to perform a new scan, dont need more bad news. It seems thats all the gyne is interested, on how I´m treating the osteoporosis but hey, hormones she wont treat. ;(

[Marinaaa in reply to Marinaaa]

I do have some information on how to deal whith the illnes via supplemnts. ortomolecular medicine, nutrigenetics but its everything in Spanish. If you are lacking this information I could try and help you. Im sure there must be in English somewhere too. Only so far I dont know.

[WeeB in reply to CoeliacMum1]

H, Im so sorry to read what you’re going through . i appreciate you sharing on here .

Can i ask , do you have any articles or website links in relation to oestrogen affecting t4-t3 conversation . I am having an issue with conversion just now and been on hrt for 18 months so just wondering if i should trial reducing my patch too .

[CoeliacMum1 in reply to WeeB]

It’s not so much a HRT problem, actually I was more balanced for a time with added progesterone and Estradiol is the good stuff, we have different types of oestrogen , I’m not getting rid of used oestrogen due to bad detoxification it’s thought… I eat more fibre than most take magnesium which helps… my insulin could be lower though.

Conversion can be other hormones like insulin cortisol or genetic… it also gets converted all over your body so if something is off you need to find cause.

Dr Louise Newson website has this about menopause & thyroid

balance-menopause.com/menop...

I haven’t checked this out but explains roughly what I mentioned.

mariongluckclinic.com/blog/...

Just google oestrogen and conversion of thyroid hormone there’s others, if need more.

[CoeliacMum1]

balance-menopause.com/

Read related articles to your symptoms here she’s a leading doctor in women’s health here in U.K.

Our guidelines are, over 45s blood tests aren’t diagnostic for menopause it’s symptoms based …as there’s too much variability in hormones it can only give a peek into things and why symptoms are now used… it’s explained fully in the link you can look at other related hormones issues in the link too.

I too heard that stabilising hormones after menopause for some do lessen the symptoms and spread, but unless endometriosis adhesion are removed they still can cause problems… some hormones haven’t been the cause so it’s believed also it’s a genetic or immune response.

I can’t eat gluten so I have the buckwheat (Saracen) and brown rice and guess dairy is my only other possibility for inflammatory diet, unless I have problems with things like nightshade, lectins anti nutrient types, which aren’t showing up in as gut related symptoms.

I’ve heard about the supplements you mention, but at present I only take Magnesium complex and vitamin D3 with K2 and B12 shots for my conditions.

I’ve read regarding N-acetyl cysteine - NAC if is possibly good for some PCOS - polycystic ovarian syndrome patients as it lowers testosterone.

lifecodegx.com/products

I have followed these (see link) for a while and have been interested in nutrigenomics for couple of years and our unique epigenetics and some not so unique, can contribute to our health problems… we can be lacking or needing more of some things for various reasons, these areas don’t change our DNA just helps the sequence so this is reversible with the right nutritional support. Detoxification and Methylation being an area I have looked at, at the moment, so I have come across those supplements that are meant to help those areas.

I have a Dexa to compare to and see if much more damage is done …I know my degenerative discs had worsened over past few years as my condition was thought to be skeletal problem so numerous MRIs but nothing out of the ordinary was found just age related wear and tear. I turned to thyroid as extremely poor FT3 and conversion problems, but dead end until read excess oestrogen can cause problems and started looking here and bingo… found these problems which could explain the pain.

Good you find answers soon.

[Marinaaa in reply to CoeliacMum1]

Its also very important avoiding processed foods, so I try reading labels and try to avoid them. I will send some articles when I have more time if I can find them in English, they say these suplements NAC and others have had superior success to hormonal treatment, and can diminsish implants and adherences. I hope so.

what were you saying about T3? I didnt quite get it, you see English is not my first language. My sympthoms were much worse when I was only in levo. They have improved considerably since I started on both.

[CoeliacMum1 in reply to Marinaaa]

I had been on just T4 meds for a decade then I tried T3 meds for a year alongside T4 meds. I was better initially but after 3months my levels were low and didn’t see anymore progress I upped the Levothyroxine and achieved same status…as my conversion from T4-T3 is poor and I have very low in range FT3 blood test results, regardless if on Liothyronine . My journey has lead me to look at sex hormones and thyroid health …given I was having abnormal bleeding, late menopause and since found these gynaecological issues.

Thyroid does well when progesterone is good and it’s usually the first thing to start to decline as we go into perimenopause (may not for all) and although oestrogen may still be low you can be oestrogen dominant as your progesterone can be even lower… I read there is a connection with oestrogen blocking thyroid hormones, so when we are out of balance this can cause us thyroid problems. So only my opinion, if you are experiencing oestrogen dominant gynaecological conditions and also have low thyroid hormones this is one of possibly more areas to look at… we are all different I do have detoxification issues so used oestrogen is often recirculating and that’s not good and causes inflammatory conditions.

Agree processed food is not way to go at all. Avoid and gluten free alternatives are worse in my opinion. I make my own food from scratch I have time … I don’t use ready made sauces, or eat biscuit breads or cakes often, I don’t have a sweet tooth… I snack on nuts and have a square of 85% dark chocolate if want some things sweeter. I buy higher fibre pasta which I I have once a week… I make my own cakes using various flours but some are rice based, but really it’s negligible in how much I actually eat as it’s shared out.

I will gather information on these supplements and see if my gynaecologist is any the wiser …I expect not, but he may have experienced others having desired outcomes even if he hasn’t much knowledge, I go mid June.

[Marinaaa in reply to CoeliacMum1]

ncbi.nlm.nih.gov/pmc/articl...

[Marinaaa in reply to CoeliacMum1]

ncbi.nlm.nih.gov/pmc/articl...

[Marinaaa in reply to CoeliacMum1]

cheese yes or no? very contradictory information regarding milk and cheese etc.

[CoeliacMum1]

Thanks for the information although both links are on studies on animals (mice) only human parts studied was after an hysterectomy from what I quickly saw when looked over them.

There’s a certain criteria to studies if I want to put to medical professionals - not that even those that are gold standard make any difference when it’s right in front of them…it’s what they believe/taught and then hard to budge unless you find an open minded person.

I will look into the supplements I don’t trust manufacturers comments as obviously they want you to try/buy these things, but from a quick Google I can see some interesting things.

Re dairy not sure what you mean, but it wasn’t thought I had any aversion to it when saw dietitian for my coeliacs disease but I have since read constipation can still be a dairy problem and something I have never tried.

[Marinaaa in reply to CoeliacMum1]

No, the second is a study on italian women. And here is a more recent one. pubmed.ncbi.nlm.nih.gov/369... they got superior results to those obtained with hormones. I´m giving it a try. I already tried it in the past for thyroid and I have it at home, just NAC, not the whole supplement I sent you. That one has bromeline (brocoli) which lowers estrogens, I¨m not sure mine need any more lowering.

I dont think your gine will know about it. I´m visiting a dr who I know works with this stuff (a gine) and see what she says about combining it with something else or giving it a try by itself. But the majority of gines dont work with these supplements, this is more for physiotherapists and so on.

In my case, I think in the past I was certainly hyperstrogenic, when I had my tyroid untreated for who know how long and since I started on monotherapy with levo, because I have only a few tests from those years and they show that and my prolactin high, and I felt really bad and had menopausal sympthoms in my early thirties and then a couple of years ago when I started introducing T3 my sympthoms improved, my estrogen lowered prolactin lowered as well, I started sleeping well and my cycle reduced in quantity, also my stomachaches reduced a lot because that had been a problem and I was only treated with benzodiacepinas because they attributed it to anxiety when now I wonder that must have been the endometriosis.

Because they saw a quist but after a year it was gone, but I wasnt told it was an endometrioma, she only said, this is only a problem for getting pregnant.

I spent years eating super healthy, which was so tiring, and to be honest, since I started on t3 and my stomachaches reduced I started eating more relaxed, and lately I was eating a lot of sugary things, milk without lactose and everything.....

So now I¨ll go back to the diet I guess which I feel so tired about, and its also difficult to keep it socially, but lets hope the quist may go away this way. Anyway, my progesterone must be very low these times so that could be a reason to its re-apperance that I cannot really control.

I see that your tried T3 without much improvement in labs. However, in my labs sometimes improves, sometimes it goes down. But my sympthoms have, a lot. I have a checklist with sympthoms, and specially mental clarity has improved. I speak good English and when I¨m low i realise I cannot find my words, I feel stupid. That helps me to check. I started with 12, now taking 25, at the moment labs are low, dont know why, I might increase or wait if I get better by itself.

Did your period bleding decrease a bit with T3, or your endo sympthoms?

[CoeliacMum1 in reply to Marinaaa]

Nothing changed really for me long term on Liothyronine although I lost weight naturally over a stone over the year, so it was good in some respects…so guessing it increased my metabolism I’m guessing but don’t know, my heartrate was higher but not too much, didn’t monitor temperature … I monitored heart on Apple Watch sending ECG from that to my endocrinologist twice a year as he was concerned about arrhythmia … I have episodes where my aches and pains were better but have been when on higher T4 meds too. My creatinine improved on one test not do on another so that’s not really conclusive, as I have higher creatinine but no kidney disease my GP says, it’s thought it’s my normal level it’s been same for well over a decade.

I didn’t know I had gynaecological issues other than having mid cycle bleed for (nearly 30yrs) GPs wasn’t concerned and Mittelschmerz nearly every month… my pelvic lower back pain wasn’t being considered as gynaecological…even though I had asked… it took another bad episode and seeing an out of hours Dr reporting back that it’s sounds gynaecological my GPs were stubborn to agreee for me to be referred. This only was found last year although in 2021 adenomyosis was found I was having abnormal bleeds on hrt but GPs still not convinced… until second time and I’m still under gynaecologists.

I appreciate gynaecologists may not know about supplements but it’s worth mentioning …I will look again at links.

[Marinaaa in reply to CoeliacMum1]

what about your cholesterol? did it change? your Fsh levels? mine were always superlow(not real, I mean) and then they suddenly increased.

[Marinaaa in reply to Marinaaa]

i dont know if your heart rate changed much but for me, having a bradicardia, a dose of 10 would have barely done nothing. Even with current dose still pretty low.

[CoeliacMum1 in reply to Marinaaa]

My cholesterol has been always low to good and triglycerides low

In past 2-3years there’s been a slight increase but still classed as good and still low triglycerides, but whilst on Liothyronine still low Cholesterol .

My blood sugar levels went up after going gluten free and guess the rice based diet isn’t good for that as I don’t eat much processed foods really and I’m not exercising as the pain is too much I still try but some days it’s hard to even stand to make food… so the excess glucose isn’t being used in my muscles.

Now on these injections Ive been told it can cause high blood sugar blood pressure and alter hormones.. I’ve had the headaches migraines hot flushes and bone pain with it the last 14days maybe… only positive so far is bleeding stopped… I go in June to see gynaecologists.

My FSH levels have not been looked at for quite some time after 45 they don’t really check I’m 58 in couple of weeks. They were checked approximately at age 47 though when I had started with more severe pain symptoms… was told I wasn’t menopausal that’s all it’s back when I didn’t really look into things as I now… when my daughter did her doctorate I started researching too.

[Marinaaa in reply to CoeliacMum1]

For glucose, eating with protein (animal preferably) at every meal, it´s convenient. Then eating wholemeal cereals, black rice, quinoa, mijo, sarracen spaguetii I quite like, cook your own sarracen bread for example. I suppose you already know all this. I small part of cereal in every meal as well. Plenty of veggies and fruits.

Chromium helps to lower blood sugar.

For endometriosis exercising daily is part of the recovery. I have read. In one congress on endometriosis is where I found the recommendation of the NAC and the supplements I adviced. I will send you the translation when I can prepare it. I have made photographs of slides.

Therapy with TENS transcutaneous electrical nerve estimulation is used to block pain. It can be used by the patient at home. You put electrodes on pelvis skin that give a vibration which is faster than pain fibres therfore as the nervous pulse travels faster, it starts inhibitory neurons that block pain fibres, therefore closing the painful sensation. They can be bought online. Do you have lots of pain or is it more a fatigue general sensation?

Apparently they say chronic pain stays on the brain for longer. I tend to hate this theories of pain as I associate it with them saying its coming back to all "mental" psychological pain theories which I find tend to substitue real treatment of pain, but just in case for you to know about it.

I personally have this mattress and use on bed. I love it.pranamat.es/eshop there are imitations in the market as well.

I am so sorry you are feeling unwell, and hope you can recover soon.

[CoeliacMum1 in reply to Marinaaa]

I understand psychosomatic effects I have read all about it … my daughter is a doctor, a psychologist and a good book to read is..

The Body Keeps the Score, by Bessel van der Kolk

You can get it in Spanish also.

Even neurologist struggle with why we hurt an example is when a person has an amputated limb they can still feel pain in it … but obviously limb isn’t there but neurones obviously remember, along with past traumas which we haven’t processed.

Berberine I’ve read is as good for blood sugar probably less side effects to metformin.🤷🏻‍♀️

At moment we think the adhesions of Endometriosis possibly on nerves and ligaments and bowel are what are causing my problems…Adenomyosis maybe too but my pain unless it’s nerve related from facet syndrome due to degenerative discs, could be the other answer … I was due to start spinal injections but we found endometriosis so looking at this, it makes more sense given the nuances had with gynaecological issues.

My oestrogen dominance is possibly inhibiting conversion but only my thoughts and although supplements may help certain aspects in my journey I need to know cause then work to help this area.

My pain at present is like a knot in buttock it causes sacroiliac like pain, which can be excruciating and struggle to walk or rise from seated a good day is dull ache in front and side of upper thigh … I know I have too much movement there (hyper mobility in hips and pelvis also) no amount of strengthening exercise has helped or physiotherapy. I get tightness around my stomach along bloating on a flare but not great deal if stomach pain it causes stiffness in my back and pelvis … over years I am more relaxed as know being uptight isn’t good for this but it cause me to cry out then just deal with it… I guess if this doesn’t work they know taking ovaries away is pointless I know hysterectomy can only help adenomyosis.

I’m just at beginning of this so a lot to learn.

[Marinaaa]

Your estrogen dominance could be inhibiting conversion or not. I think that estrogen dominance can be treated with supplements and the healthy eating you are already doing. If your daughter is a doctor, you could ask her to get informed about supplements, nutrigenomics works wonders with this. There is vitex agnus castus, onagra, maca, pulsatilla, brócoli, chrome, vitmaine B, taurine, curcumine, supramineral desmodium etc.

However, my point is that it is low thyroid hormone (low Ft3) which definately creates an excess estrogen in the body. So that might be (low FT3 causing low estrogen) what could be driving your endometriosis to a worse extent.

It is not only because it creates excess estrogen but because the paths of detoxification are even more impaired when you are undermedicated or your body is in a hypo state. They generally are impaired to a certain extent in some people who dont convert well, or it maybe just that thyroid is too ill to convert, but if you sum up that impairment in detoxification with less hormones helping in the detox, the effect multiplies. Clearly the more in balance your thyroid hormones are, the better your body is ready to fight the enemy, so to speak.

Bear in mind that some people still keep and grow adhesions after histerectomy, so I would be looking into other areas a.s.a.p. Because this illness is not only produced by estrogen dominance, there is an inmunological influence as well.

When my gine learnt about the diagnosis, she ordered TSH and T4, because acording to her, it was related. How is she going to fix it this way? In the past my older gine and endo kept me with a TSH around 4... imagine my FT3 well they never checked so.... how were they going to help me with the endometriosis?

Thats why nowadays I study and search myself. 😀