Help with results please: Received results of... - Thyroid UK

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Help with results please

DaisyTed profile image
9 Replies

Received results of Medichecks Well Women tests last week (blood test taken at 9.30am fasted, last dose of Levo 24 hrs before and biotin supplements stopped for a week before).

Results - TSH 2.68 (0.27-4.2), Free T3 3.98 (3.1-6.8) and Free thyroxine 19.5 (12-22).

Vitamin D 63nmol/L (range 50-200) - I take vit D spray 25 mcg daily.

Vitamin B12 Active 50.1 (37.5-150)

Ferratin 36.8 (13-150), Transferrin Saturation 16.8% (20-50).

white cell count also low - neutrophils 1.88 (2-7.5), monocytes 0.17 (0.2-1).

I am on a gluten free and dairy free diet and have noticed big improvements in gut symptoms since changing to GF and DF. I upped my Levo dose to 75 in March with immediate improvements in fatigue and brain fog, but these have worsened again in the past month, so I’m guessing I need another dose increase to 100mg. I am planning to write to my GP to request this, as otherwise it will be a difficult conversation over the phone. I am planning to include evidence-based references that I have gleaned from all the helpful advice here! Am assuming low vit D and B12 result due to poor absorption because thyroid function isn’t optimised?? Any other tips before I send the letter gratefully appreciated - I have learnt so much from this forum.

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DaisyTed
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DaisyTed profile image
DaisyTed

SlowDragon tattybogle any advice please??

SlowDragon profile image
SlowDragonAdministrator

yes dose increase to 100mcg

Was last dose levothyroxine 24 hours before test

Because Ft4 is quite high……Perhaps initially to 87.5mcg daily

Which brand of levothyroxine are you currently taking?

Vitamin levels are all poor

Exactly What vitamin supplements are you taking

DaisyTed profile image
DaisyTed in reply toSlowDragon

Thanks so much SlowDragon - I take Accord 50 and Teva 25 at night-time just before bed. Prior to the blood test I took 50mg 24 hrs before the test and 25 the night before that. I take Vitamin D spray 25 ug from Holland and Barrett and Floridix tablets. I have also been taking NU Mind All in One stress support supplement for the last few weeks on recommendation from a nutritionist who felt I was a bit stressed (it contains vitamin B, Vitamin C, Zinc, Iron, vit D, magnesium amongst other things..)

Would 87.5mcg be the same as 75 one day, 100 the next? What is my conversion rate like? Many thanks again for your help 😊

SlowDragon profile image
SlowDragonAdministrator in reply toDaisyTed

FT4: 19.5 pmol/l (Range 12 - 22)

Ft4 is 75.00% through range

FT3: 3.98 pmol/l (Range 3.1 - 6.8)

Ft3 only 23.78% through range

Helpful calculator for working out percentage through range

thyroid.dopiaza.org

Improving vitamin levels should hopefully improve conversion rate

Suggest you always get same brand levothyroxine at each prescription

Teva brand upsets many people

Accord don’t make 25mcg tablets

Get GP to increase number of 50mcg tablets prescribed per month

Cut in half to get 25mcg

Yes 87.5mcg = 100mcg one day and 75mcg the next day

Mercury Pharma make 25mcg, 50mcg and 100mcg tablets 

Mercury Pharma also boxed as Eltroxin. Both often listed by company name on pharmacy database - Advanz

Accord only make 50mcg and 100mcg tablets. Accord is also boxed as Almus via Boots, 

Wockhardt is very well tolerated, but only available in 25mcg tablets. Some people remain on Wockhardt, taking their daily dose as a number of tablets 

Lactose free brands - currently Teva or Vencamil only

Teva makes 25mcg, 50mcg, 75mcg and 100mcg

Many patients do NOT get on well with Teva brand of Levothyroxine.

Teva is lactose free.But Teva contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome 

Teva is the only brand that makes 75mcg tablet.

So if avoiding Teva for 75mcg dose ask for 25mcg to add to 50mcg or just extra 50mcg tablets to cut in half

But for some people (usually if lactose intolerant, Teva is by far the best option)

Aristo (currently 100mcg only) is lactose free and mannitol free.

March 2023 - Aristo now called Vencamil

healthunlocked.com/thyroidu...

List of different brands available in U.K.

thyroiduk.org/if-you-are-hy...

SlowDragon profile image
SlowDragonAdministrator in reply toDaisyTed

I have also been taking NU Mind All in One stress support supplement for the last few weeks on recommendation from a nutritionist who felt I was a bit stressed (it contains vitamin B, Vitamin C, Zinc, Iron, vit D, magnesium amongst other things..)

This one?

numindwellness.com/products...

This contains iodine, not recommended for anyone with Hashimoto’s

multivitamins never recommended on here

Multivitamins

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Contains biotin, so did you stop this 5-7 days before test

SlowDragon profile image
SlowDragonAdministrator

Vitamin D 63nmol/L (range 50-200) - I take vit D spray 25 mcg daily.

Is this Better You mouth spray - which one , blue, green or red

Try increasing to 2 or 3 sprays a day for 2 months then retest

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

Better You do a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Vitamin D and thyroid disease

grassrootshealth.net/blog/t...

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

SlowDragon profile image
SlowDragonAdministrator

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement and add a separate vitamin B Complex after a week

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

Thorne currently difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

Other options

healthunlocked.com/thyroidu....

Igennus B complex popular option too. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator

Ferratin 36.8 (13-150),

Transferrin Saturation 16.8% (20-50).

emedicine.medscape.com/arti....

Request FULL iron panel via GP - saturation below range

cks.nice.org.uk/topics/anae...

Serum ferritin level is the biochemical test, which most reliably correlates with relative total body iron stores. In all people, a serum ferritin level of less than 30 micrograms/L confirms the diagnosis of iron deficiency.

Never supplement iron without doing full iron panel test for anaemia first and retest 3-4 times a year if self supplementing. It’s possible to have low ferritin but high iron

Medichecks iron panel test

medichecks.com/products/iro...

Look at increasing iron rich foods in diet

Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

healthunlocked.com/thyroidu...

Posts discussing Three Arrows as very effective supplement

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Iron patches

healthunlocked.com/thyroidu...

Thyroid disease is as much about optimising vitamins as thyroid hormones

healthunlocked.com/thyroidu...

restartmed.com/hypothyroidi...

Post discussing just how long it can take to raise low ferritin

healthunlocked.com/thyroidu...

Iron and thyroid link

healthunlocked.com/thyroidu...

Excellent article on iron and thyroid

cambridge.org/core/journals...

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

Good iron but low ferritin

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Chicken livers if iron is good, but ferritin low

healthunlocked.com/thyroidu...

Shellfish and Mussels are excellent source of iron

healthline.com/nutrition/he...

Ferritin over 100 to alleviate symptoms

healthunlocked.com/thyroidu...

Great research article discussing similar…..ferritin over 100 often necessary

ncbi.nlm.nih.gov/pmc/articl...

Low Iron implicated in hypothyroidism

healthunlocked.com/thyroidu...

Ferritin range on Medichecks

healthunlocked.com/thyroidu...

Inflammation affecting ferritin

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

We have received further information the lab about ferritin reference ranges. They confirm that they are sex dependent up to the age of 60, then beyond the age of 60 the reference range is the same for both sexes: 

Males 16-60: 30-400 ug/L

Female's: 16-60: 30-150

Both >60: 30-650 

The lower limit of 30 ug/L is in accordance with the updated NICE guidance and the upper limits are in accordance with guidance from the Association of Clinical Biochemists. ‘

DaisyTed profile image
DaisyTed

wow so much helpful information here! I hadn’t realised the stress support capsules had iodine in.. thanks for spotting that. Will work through all the info you sent to get my vitamin levels improved etc. thanks so much! 🙏

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