your wonderful insights to my results would be very much appreciated. hoping to see GP on Monday.

[Auders]

Nov 21 T4 16.2 [10-22] TSH 4.8 mu/L [0.3-4.2]

Dec 21 T4 17.2 [10-22] TSH 4.3 mu/L [0.3-4.2]

Started trial of 25mcg Levo (Teva brand)

April 22 TSH 5.2mu/L [0.3-4.2]

Dose 50mcg Levo (Teva)

May 22 TSH 3.3 [0.3-4.2]

Dose 62.5mcg (50mcg MP and half Wockhardt 25mcg)

TSH 3.77mu/L [0.27-4.2] July M

TSH 2.9mu/L [0.3-4.2] August G

FT4 17.2pmol/L [12-22] July M

FT3 4.1pmol/L [3.1-6.8] July M

Thyro Anti 14 iu/ml [0-115] July F

TPO 10 iu/ml [0-34] July F

Active B12 >300pmol July F

Folate 15.4ug/L [>2.9] August S

Vit D 93nmol/L July M

Vit D (250H) 92nmol/L [50-200] July F

Iron 11.2umol/L [5.8- 34.5] July Med

TIBC 67.4umol/L [45-81] Juky Med

Transferrin 16.6% [20-50] July Med

Ferritin 59.3ug/L [13-150] July Med

CRP hs 12.97 [0-5] July Med

Cortisol 575nmol/L [>557.7 high] July F

EGFR 54/min [<60] July G

HBA1c 49mmol/L [>48] August G

Total Cholesterol 3.9mmol/L [0-5] August G

HDL 1mmol/L [<1.2] August G

Non HDL 2.89mmol/L [<4] August G

Triglyceride 1.0mmol/L [,4.5] August G

LDL 2.4mmol/L [0-3} July F

HDL ratio 3.9 [0-6] july F

All other bloods were in range. Bloods done as per recommended regime. Other medications taken Omeprazole (not takinh daily now) Naproxen (only when in dire need) Delenium (healthspan) Thorne Basic B complex, Nature provides 3000iu D3+K2MK and Nature provides Mag Glycerine X2 at night (if I remember) thank you for reading this lot. Would very much appreciate any input. Hoping to push for another dose increase. Thanks again

[Auders]

Oh forgot to say, I used several different brands for the tests, M =MMH, Med= Medichecks, G=GP, F=Forth (sent to same PO Box in Exeter as MMH) and S=SurerdrugOnline.

[SlowDragon Administrator]

TSH 3.77mu/L [0.27-4.2] July M

FT4 17.2pmol/L [12-22] July M

FT3 4.1pmol/L [3.1-6.8] July M

TSH 2.9mu/L [0.3-4.2] August G

July results

FT4: 17.2 pmol/l (Range 12 - 22)

Ft4 only 52.00% through range

FT3: 4.1 pmol/l (Range 3.1 - 6.8)

Ft3 only 27.03% through range

Were all tests done early morning, ideally before 9am and last dose levothyroxine 24 hours before test

You need increase in dose levothyroxine to 75mcg every day

Retest in another 6-8 weeks

[Auders in reply to SlowDragon]

Thanks for your reply, all bloods done before 09.00 and 24 hrs after last dose. 🙏

[SlowDragon Administrator in reply to Auders]

Work on improving ferritin to nearer 100

Just by increasing iron rich foods in diet

Get levothyroxine dose increase

All four vitamins optimal for best conversion

You could try splitting your levothyroxine dose….half dose waking and half at bedtime

Some people find it improves conversion too

[Auders in reply to SlowDragon]

Oh thanks for that advise. Really hoping the Gp will agree to me trying 75mcg, but I could try 50mcg morning and 25mcg at night? Didn’t know about splitting the doses that it can improve conversion, interesting 🧐

[SlowDragon Administrator in reply to Auders]

Yep …could try that

[Auders in reply to SlowDragon]

Will definitely give it ago. Just hoping Gp isn’t too focused on EGFR! Also was concerned over CRP ha levels. It’s an on going battle isn’t it?

[SlowDragon Administrator in reply to Auders]

Low GFR directly linked to low thyroid hormones, especially low Ft3 …..but don’t be surprised if GP has no idea

Suggest you print this link out

ncbi.nlm.nih.gov/pmc/articl...

Hypothyroidism is associated with reduced GFR

The GFR is reversibly reduced (by about 40%) in more than 55% of adults with hypothyroidism[40] due to several reasons.

tandfonline.com/doi/full/10...

Hypothyroidism is an underappreciated cause of renal impairment.

Primary hypothyroidism is associated with a reduction of GFR and RBF that are normalized following levothyroxine administration.3,8,10–12 Similarly, normalization of circulating TH concentrations with replacement therapy in hypothyroid patients with chronic kidney disease (CKD) can significantly improve GFR.13

[Auders in reply to SlowDragon]

Wow! I did not know that either. Thank you so much I’ll have a good read of that and take a copy with me 🙏