Experiences with

Metabolic conditions

Protein Misfolding and Aggregation: • Both proteins misfold and aggregate under conditions of oxidative stress and metabolic dysregulation. • Aggregates of both proteins are toxic to the cells where they accumulate (beta cells in diabetes, neurons in Parkinson’s). 2.

The other day I fell across a paper: The role of lipoprotein(a) in atrial fibrillation: a systematic review. https://europepmc.org/article/MED/39791840 Within that paper, I specifically noticed in their reference 28: Conclusion Low circulating Lp(a) levels were associated with AF, especially

I got to a better place with my fibro with a healthy diet, water, exercise, low dairy, low gluten, and low sugar. I've fallen into all of the opposite over Christmas and can't believe how poorly I feel. I've also come off vitamins as my GP said I have high iron and B12. Trouble is the pain stops you

So, I haven't had any RLS in many years - until the last 2 nights! Mostly my severe RLS was settled years ago with iron supplements (ferrous bisglycinate chelate). I have been taking berberine to help with cholesterol support - in the morning (500mg). I recently had my cholesterol checked and decided

My ctDNA summary attached. Low intermediate TMU. And, a list of Variants of Uncertain Clinical Significance (VoUCS) but no other smoking guns. My PROMISE COLOR germ line results were ‘clean’. Here are most of the VoUCS. The major VoUCS gene/protein is SETD2 F341Y (5.4%). Google has SETD2 as a DNA

https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/157202-total-prostate-specific-antigen-psa-testing-in-capillary-samples-proof-of-principle-and-feasibility-study-for-home-self-testing-for-prostate-cancer.html Cool if it it becomes reality, so we can maybe finger prick onto

Thyroxine increased from 100mcg by tiny amount recently due to increased TSH. (25mg over 4 days - quartered tablets). Managed to tolerate for about 6 weeks but felt increasingly unwell, anxious, over medicated. Would appreciate your input before appointment with NP/GP: also on Ferous numerate as was

hi all So the past few days I’ve been having symptoms of over medicated - hot flushed, sweating, not being able to sleep AT ALL, palpitations and just generalised jitteriness. my results 2nd December were: TSH 0.77 (0.35-4.94) T3 5 (3.1-6.8) T4 13 (9-19) Increased to 100mcg levo from 75mcg 10 weeks

I was give this when I got covid it's left me to breathing problems a year in I got covid again I was supposed to have a spirow monitor but I've not been because I'm so scared the salamol always stop I clean them once a week I've to ring my doctor's for a new one but they want give me another one I do

I recently posted my latest presentation about Parkinson's and nutrition here https://www.youtube.com/watch?v=W7kT4OonMV0. I call it a ketogenic lifestyle. I combine a ketogenic diet with MCT oil and sufficient exercise. (The presentation is in Dutch. Most here will not be Dutch speaking and can use

Hello, Has anyone used or using DHA and Ketone / MCT / Coconut oil? Please share your experiences / suggestions.

Hello Everyone , Fasting blood sample taken in the morning (11:30am, T3 taken at 7:30am) . Stopped biotin couple of days before. Below are the latest blood test results. (December 2024). FREE T3 6.3 pmol/L 3.1 - 6.8 CREATININE 118  umol/L Please note method changed to enzymatic and ref range

I’m Darryl Mitteldorf, the social worker who started Malecare. Malecare amplifies patient voices, drives research focusing on quality of life and underserved communities, and addresses patients' real-life concerns. I started Malecare in 1998 when I identified a problem in the healthcare system: the

Hi all, I was on Tirosint initially 50mg which work r really well but I still had cold extremities and mild muscle fatigue leading up to my period so my doctor put me on 75mg Tirosint every two days which was horrific. I dropped back down to 50mg Tirosint and was then place on NDT grain 1 and taken

Difficult subject but perhaps worth some discussion! I just read a post on the forum which made me sad for the daughter of a gentleman who was littered with cancer and had a heart attack but they were able to revive him. However he is now in what appears to be in a coma status. Wondering what your

Hopefully an encouraging share! Self-directed T and uPSA results in today. This past April my T was down to 350, today 422; no supplements. This past March my uPSA reached a high of 0.037. Today 0.029; no ADT. Overall, my uPSA has been holding very low stable 0.03X range since June 2021, with increasing

I have an underactive thyroid and take 75mcg of Levothyroxine. I have just been diagnosed with high cholesterol and advised to take statins. Having read information on this I am a little apprehensive about taking them. Can anyone advise me if it's better to reduce cholesterol by diet or take statins

I was looking for information regarding cholesterol medication "ezetimibe" and I came across this article. There seams to be a relation between regulating lipid accumulation and CLL. I am currently not taking ezetimibe but I do plan to have a conversation with my doctor to see if we should consider

There are regular posts and snippets about Ketones and Ketone diets. This is an attempt to provide a more definitive post and reference. I’ve tried to keep it simple and jargon free as much as possible. This attempts to provides information on the following areas. 1. What is a Ketone, how and why

Update, after seeing my Endo for 1st time & cortisol being ok I have struggled to get to the trail stage as suggested as where I live the NHS trust have T3 black listed, written to Health Secretary - no reply, MP - no reply, head of NHS Trust a lovely lady emailed to discuss my "complaint" answered all