Naproxen is a medicine that reduces inflammation and pain in joints and muscles.
Naproxen is available on prescription as tablets or as a liquid that you drink. You can buy it without a prescription from a pharmacy for period pain.
Naproxen can only be taken by children when it's prescribed for them.
Who can and cannot take naproxen
Most adults can be prescribed naproxen.
It can also be prescribed to children to treat:
- muscle and bone disorders for babies from 1 month
- diseases of the joints for children from 2 years
- period pain – for children under 15
Adults and teenagers aged 15 and over can buy it from a pharmacy for period pain.
Naproxen is not suitable for certain people. Tell your doctor or pharmacist if you:
- have had an allergic reaction to naproxen or any other medicines in the past
- have had an allergic reaction to aspirin or other non-steroidal anti-inflammatory medicines (NSAIDs), such as ibuprofen
- have or have had stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach
- have high blood pressure
- have severe liver or kidney failure
- have severe heart failure or other heart problems
- have Crohn's disease or ulcerative colitis
- have lupus
- have a blood clotting disorder
- are pregnant, planning to become pregnant, or breastfeeding
How and when to take naproxen
Always take your naproxen tablets with or just after a meal so you do not get an upset stomach.
As a general rule in adults, the dose to treat:
- diseases of joints is 500mg to 1,000mg a day in 1 or 2 doses
- muscle, bone disorders and painful periods is 500mg at first, then 250mg every 6 to 8 hours as required
- attacks of gout is 750mg, then 250mg every 8 hours until the attack has passed
Doses are usually lower for elderly people and people with heart, liver or kidney problems.
The doctor will use your child's weight to work out the right dose.
If you get naproxen on prescription, the dose depends on the reason why you're taking it, your age, how well your liver and kidneys work, and how well it helps your symptoms.
If you buy naproxen from a pharmacy for painful menstrual periods:
- on the first day – take 2 tablets when the pain starts, then after 6 to 8 hours take 1 more tablet that day if you need to
- on the second and following days – take 1 tablet every 6 to 8 hours if needed
Do not take more than 3 tablets in 24 hours for period pain.
Naproxen on prescription comes as 2 different tablets: effervescent and gastro-resistant tablets.
Effervescent tablets are dissolved in water before you take them.
Gastro-resistant tablets have a coating to protect them from being broken down by the acid in your stomach. Instead, the medicine is released further down the gut in your intestine.
If you take gastro-resistant tablets, swallow them whole with or after food. Do not crush or chew them.
If you take effervescent tablets, dissolve 1 to 2 tablets in a glass (150ml) of water and drink.
Doses of 3 tablets should be dissolved in 300ml. To make sure there's no medicine left, rinse the empty glass with a small amount of water and drink it. Take with or after food.
What if I forget to take it?
Take your forgotten dose as soon as you remember, unless it's nearly time for your next dose.
Do not take a double dose to make up for a forgotten dose.
If you forget doses often, it may help to set an alarm to remind you.
You could also ask your pharmacist for advice on other ways to help you remember to take your medicine.
What if I take too much?
If you take too many naproxen tablets, you're more likely to get some of the common side effects. Contact your doctor straight away.
Taking naproxen with other painkillers
Do not take naproxen with ibuprofen or other NSAIDs.
If you often need to take extra painkillers with naproxen or for more than a few days, you should talk to your doctor or pharmacist.
Sometimes taking different painkillers together is a good way to relieve pain, but there may be other treatments you can try.
It's OK to take other painkillers with naproxen for longer if your doctor has given them to you on prescription and told you to take them together.
If you're unsure, talk to your pharmacist or doctor.
Like all medicines, naproxen can cause side effects, although not everyone gets them.
Common side effects
Common side effects of naproxen happen in more than 1 in 100 people.
- ringing in the ears
- changes in vision
- tiredness and feeling sleepy
Talk to your doctor or pharmacist if these side effects bother you or do not go away.
Serious side effects
Call your doctor straight away if you have:
- severe indigestion, heartburn, pains in your stomach, feeling or being sick (nausea or vomiting) or diarrhoea – these can be signs of an ulcer or inflammation in the stomach or gut
- vomiting blood or dark particles that look like coffee grounds, blood in your poo, or black, tarry-looking poo – these could be signs of bleeding and perforation of the stomach or gut
- a frequent sore throat, nose bleeds, and infections – these can be signs of abnormalities in your blood cells, known as agranulocytosis
- fainting, chest pain, or breathlessness – these can be signs of anaemia
- high temperature, feeling or being sick, confusion, headache, neck stiffness and sensitivity to light – these can be signs of aseptic meningitis
- blood in your pee, a decrease in how much pee is passed, feeling or being sick – these can be signs of kidney damage or infection
- yellow skin or the whites of your eyes turn yellow – these can be signs of jaundice or inflammation of the liver
- irregular, slow heartbeats caused by high levels of potassium in the blood
- high temperature, stomach pain and being sick – these can be signs of inflammation of the pancreas
Serious allergic reaction
In rare cases, it's possible to have a serious allergic reaction to naproxen.
How to cope with side effects of naproxen
What to do about:
- confusion – if naproxen makes you feel confused, speak to your doctor.
- headache – make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Headaches should usually go away after the first week of taking naproxen. Talk to your doctor if they last longer than a week or are severe.
- ringing in the ears – if this lasts for more than 1 or 2 days, speak to your doctor as they may need to change your treatment.
- changes in vision – do not drive until this side effect has worn off.
- feeling sleepy, tired or dizzy – as your body gets used to naproxen, these side effects should wear off.
- dizziness – if naproxen makes you feel dizzy, stop what you're doing and sit or lie down until you feel better.
- rashes – it may help to take an antihistamine, which you can buy from a pharmacy. Check with the pharmacist to see what type is suitable for you.
Pregnancy and breastfeeding
Naproxen is not usually recommended in pregnancy – especially if you're 30 or more weeks – unless it's prescribed by a doctor.
This is because there might be a link between taking naproxen in pregnancy and some birth defects, in particular damage to the baby's heart and blood vessels.
There may also be a link between taking naproxen in early pregnancy and miscarriage.
Talk to your doctor about the benefits and possible harms of taking naproxen.
It'll depend on how many weeks pregnant you are and the reason you need to take the medicine. There may be other treatments that are safer for you.
Paracetamol is usually recommended as the first choice of painkiller for pregnant women.
Naproxen and breastfeeding
Naproxen is not usually recommended during breastfeeding. Other anti-inflammatory medicines, such as ibuprofen, are safer.
But if your baby is premature, had a low birth weight, or has an underlying medical condition, talk to your doctor before taking any painkillers.
Cautions with other medicines
There are some medicines that interfere with the way naproxen works.
Tell your doctor if you're taking:
- other anti-inflammatory medicines, such as aspirin or ibuprofen
- medicines that thin the blood, such as warfarin or rivaroxaban
- steroids, such as prednisolone
- medicines that make you pee more (diuretics), such as furosemide
- medicines used to treat heart problems and high blood pressure
- antidepressants, such as citalopram
- medicine used to treat rheumatoid arthritis, such as methotrexate
Gout — Link to Related Condition
Indigestion — Link to Related Condition
Period pain — Link to Related Condition
Stomach ulcer — Link to Related Condition
HealthUnlocked: naproxen forum — Link to Useful Resource
Arthritis Research UK — Link to Useful Resource
British Pain Society — Link to Useful Resource
Living with pain: videos of real stories — Link to Useful Resource
The Pain Toolkit: persistent pain — Link to Useful Resource
Women's Health Concern: period pain — Link to Useful Resource
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