I recently ordered a private thyroid test and have just received the results, and I'm not too sure about some of them.
CRP 8.61 <5.0 mg/
Magnesium 0.99 (0.7-1.0 mmol/L)
Cortisol 346.0 (166-507)
TSH 3 .21 (0.27-4.20)
T4 total 133.0 (66-181)
Free T4 16.0 (12.0-22.0)
Free T3 5.12 (3.1-6.8)
Anti-thyroidperoxidase abs 584 (<34)
Anti-thyroglobulin abs 194 (<115)
Vitamin D (25OH)4 2 (optimal 75-200)
Vitamin B12 275 (145-569)
I have been taking Levi for 6 weeks,I will just go and check the range but the result before I went on that was 4.8.
ETA these were my last results:
Se thyroid peroxidase Ab conc-> 1006 u/ml< 9.00u/ml
HbA1c 38( <48.00mmol/mol)
Serum TSHlevel 4.81( 0.27-4.20mU/L)
Serum free T4 level 12.8 (11.00-25.00pmol/L)
I would appreciate any help with this,I'm particularly worried about the CRP result as I suspected this would be high because I hurt all the time,whichi know can be from Hashisbut it worries me I have all the same aches and pains as my mum,who has arthritis,except she is in her 70's while I'm in my late 30' s.
Any insight would be greatly appreciated,as always
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Holiday74
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Did you follow the protocol we advise for doing thyroid tests:
* No later than 9am
* Water only before the test
* Last dose of Levo 24 hours before the test
* No biotin, B Complex or any supplement containing biotin for 3-7 days before the test
CRP 8.61 <5.0 mg/
This may be raised due to the Hashi's. Hashi's causes inflammation.
Magnesium 0.99 (0.7-1.0 mmol/L)
Testing magnesium is unreliable. About 99% of magnesium is stored in bone, muscles and soft tissues, leaving about 1% in the blood. So testing what's in the blood isn't giving an accurate picture of our magnesium status.
A red cell magnesium test is the better indicator of magnesium status, not the standard serum magnesium test. The red cell test is expensive and requires phlebotomy which is why it's not included in these bundles.
Cortisol 346.0 (166-507)
This would seem to be OK.
TSH 3 .21 (0.27-4.20)
TSH is reducing, as it should once on thyroid hormone replacement. Still a way to go as the aim of a treated hypo patient on Levo only, generally, is for TSH to be 1 or below if that is where you feel well.
T4 total 133.0 (66-181)
Not a particularly useful test, it's the FT4 that is more important.
Free T4 16.0 (12.0-22.0)
This is improving, now 40% through range, previously 12.86% through range. When optimally medicated it generally is in the upper part of it's reference range, possibly around 60-70% ish.
Free T3 5.12 (3.1-6.8)
Pretty good at 54.59% through range.
These thyroid results show that you are ready for an increase in your Levo as per titrating protocol which your GP should follow. 25mcg increase now, retest in 6-8 weeks and possibly further increase may then be necessary.
Anti-thyroidperoxidase abs 584 (<34)
Anti-thyroglobulin abs 194 (<115)
These confirm your Hashi's.
Vitamin D (25OH)4 2 (optimal 75-200)
Very poor and could possibly be the cause of your aches and pains. Low Vit D can cause muscle and joint aches and pains.
Your level is possibly not low enough for GP to do anything, and to be honest you'd be better sorting this out yourself.
The Vit D Society and Grassroots Health recommend a level of 100-150nmol/L, with a recent blog post on Grassroots Health mentioning a study which recommends over 125nmol/L.
You might want to check out a recent post that I wrote about Vit D and supplementing:
and you can check out the link to how to work out the dose you need to increase your current level to the recommended level.
Your current level of 42nmol/L = 16.8ng/ml
On the Vit D Council's website you would scroll down to the 2nd table
My level is between 10-20 ng/ml
Aiming for 50ng/ml (125nmol/L) you will see that they suggest supplementing with 4,900iu daily, the nearest being 5,000iu.
Retest after 3 months.
Once you've reached the recommended level then a maintenance dose will be needed to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. This can be done with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3. You will have to buy these yourself.
D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc. 90-100mcg K2-MK7 is enough for up to 10,000iu D3.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.
For D3 I like Doctor's Best D3 softgels, they are an oil based very small softgel which contains just two ingredients - D3 and extra virgin olive oil, a good quality, nice clean supplement which is budget friendly. Some people like BetterYou oral spray but this contains a lot of excipients and works out more expensive.
90-100mcg K2-MK7 is enough for up to 10,000iu D3.
For Vit K2-MK7 my suggestions are Vitabay, Vegavero or Vitamaze brands which all contain the correct form of K2-MK7 - the "All Trans" form rather than the "Cis" form. The All Trans form is the bioactive form, a bit like methylfolate is the bioactive form of folic acid.
Vitabay and Vegavero are either tablets or capsules.
Vitabay does do an oil based liquid.
Vitamaze is an oil based liquid.
With the oil based liquids the are xx amount of K2-MK7 per drop so you just take the appropriate amount of drops.
They are all imported German brands, you can find them on Amazon although they do go out of stock from time to time. I get what I can when I need to restock. If the tablet or capsule form is only in 200mcg dose at the time I take those on alternate days.
If looking for a combined D3/K2 supplement, this one has 3,000iu D3 and 50mcg K2-MK7. The K2-MK7 is the All-Trans form
Magnesium should be taken 4 hours away from thyroid meds and as it tends to be calming it's best taken in the evening. Vit D should also be taken 4 hours away from thyroid meds. Vit K2-MK7 should be taken 2 hours away from thyroid meds. Don't take D3 and K2 at the same time unless both are oil based supplements, they both are fat soluble vitamins which require their own fat to be absorbed otherwise they will compete for the fat.
Vitamin B12 275 (145-569)pmol/L = 372pg/ml
According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:
"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".
"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."
Do you have any signs of B12 deficiency – check here:
If you do then list them to discuss with your GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results and if you have B12 deficiency is not detected and treated then this could affect your nervous system. B12 deficiency should be treated before starting folic acid because folic acid can sometimes improve your symptoms so much that is masks B12 deficiency.
If you do not have any sign/symptoms you should look at supplementing to raise your level. I would suggest taking a B12 sublingual such as Cytoplan:
Also take a B Complex to keep all the B vitamins balanced. I would suggest Thorne Basic B or one that says "bioavailable" or "bioactive" and contains methylcobalamin (not cyanocobalamin) and methylfolate (not folic acid) and no Vit C which stops the body absorbing the B12 and needs to be taken 2 hours away.
One bottle should be enough, along with the B Complex. When the bottle of B12 is finished then continue with just the B Complex.
Whn taking B Complex it needs to be left off for 3-7 days before any blood test (including thyroid) as it contains biotin and this can cause false results.
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