NDT as arrived 👍

[birkie]

Hi everyone ❤️So my compounded ndt as arrived from roseway, it says to take one capsule [ 0.5 grain per capsule] does anyone know what the equivalent is in terms of t3 ,t4 intake🙈.

I've read the leaflet accompany the medication but as always I'm slightly lost as to the ratio

It says...[ T3 liothyronine is approximately four times as potent as[ T4] levothyroxine on a micro gram to micro gram basis) they provide 38mcg levothyroxine and 9mcg liothyronine per grain of thyroid.

My instructions on the bottle are take one daily 0.05 grain ] what is that in T4 , T3???

I'm bothered that 0.5grain will be to much in one go...does anyone thing I should spread it out taking half and half 🤷‍♀️

This is my first time taking ndt .

[beh1]

you say they want you to take half a grain, so approx 19 mcg T4 and 4.5 mcg T3, where T3 is around 3-4 times as potent as T4. It seems a very low dose but I haven’t read your background so maybe it’s fine, or maybe just a starter dose.

[birkie in reply to beh1]

Thanks for the reply, I've had a terrible time on synthetic thyroid hormone , and can't stomach it, I discussed everything with the roseway representative so maby this dose is as you say a starter one, or its to get my body use to it then increase after blood work..if I need to.Was just bothered it was to high a dose, as I was hypersensitivity to synthetic T3🤦‍♀️

[pennyannie in reply to birkie]

Hey there again ;

When I started on NDT - I stopped taking synthetic T4 x125mcg one day and started on 1/2 grain the following day which was around 4.50 mcg T3 + 19 mcg T4 -

- and then weekly increased my dose by 1/4 grains - so as the T4 reduced in my body I was building back up with NDT for a smooth transition from one treatment option to another.

I monitored myself on blood pressure, pulse and body temperature AM and PM - and whilst the first 2 remained constant I tracked my temperature slowly start rising from 35.4 to 36.6 where it generally sits now some 6 years on.

I got as far as 1+3/4 grains and felt a bit uncomfortable in my skin, anxious, edgey, so dropped down to the previous weeks dose - 1 + 1/2 grains where I had no symptoms - stayed on this dose 8 weeks and then ran a blood test -

my T3 was 110% with my T4 at 25 % - through the ranges - the exact opposite of when on T4 monotherapy - I wasn't aware of any negative symptoms - felt fine - and am still taking 1 + 1/2 grains 6 years later and doing ok:

Seeing as you have no T4 left in your body I would think you could go straight to 1 grain

What was suggested by the Roseway thyroid specialist when they learnt you were left with no thyroid hormone support and after a thyroidectomy for Graves Disease ?

Are you dosing once or twice a day - interested to know what the leaflet suggests !!

[birkie in reply to pennyannie]

They were very thorough, I filled in the forms and spoke to a representative.. about my journey on synthetic t4 t3 [ never done combo t4,t3] I've alway been given either t4 or t3 .

Endocrinologists looking over my bloods even writing reports to gp saying I was having absorption issues due to diarrhoea ect..but not doing anything constructive other than putting me back on t4, there go to drug🙄 [ don't get me wrong it works for some, including my own mother who was hypothyroid] but that in its self is the definition of madness, knowing I was not doing well on synthetic hormone replacement but putting me back on the very worst ..T4 ...it never restored my T3 to good levels and the silly Endocrinologists knew this....my analogy of it is like...you see a gp..you have a peanut allergy and the gp pescribes you a tablet with peanut in it and continues to pescribe it...at some point that patient will have a very bad reaction to it.

The roseway representative was more interested in getting me a compound to suit my gastric needs, which I was grateful for , I mentioned I'd been on and off thyroid medication for the last 4 and a half years coming of at periods to see if it was the synthetic thyroid giving me the side effects, which it was and to give my bowles and stomach a rest and for the inflammation to subside..which it always does👍

She obviously said it's not a good thing not taking any thyroid hormone replacement when you have no thyroid, but understood why I did it she also said to keep her informed as to how I do on this compound she as done for me🥰

[birkie in reply to pennyannie]

I've been given 0.05mcg it says take one daily , I think she wants me to start low and build up , I want to see if I can stomach it ,I'll know in around 3/4 days if its going to effect my stomach and bowels.

[Brightness14]

One half a grain is about 39 T4 and about 9 T3.

Then the 39 has to convert to the T3. This is a very low dose but it depends on what you have been taking recently. This is not synthetic T3 but natural.

[birkie in reply to Brightness14]

Yeah just trying to work out what I'm actually taking 🙈 Obviously when I was on synthetic T4, T3 I could only manage a small amount, [ stomach/ gut issues and sensitivity to the synthetic medication] so I got to 25mg t3 but couldn't stay on it...and got to just over 25mg on T4 but had to come off it for same reason.

So is 0.5 half a grain...🙈

[tattybogle in reply to birkie]

yes birkie 0.5 means 'half a grain' ,

one grain has 39mcg T4 + 9mcg T3

half a grain has 19.5mcg T4 + 4.5mcg T3

brightness' reply was incorrect.

[birkie in reply to tattybogle]

OK thanks tattybogle....so this is the million dollar question....do u think I should stay on 0.5 grain for say 5 days [ if I get past 5 days without any stomach and gut issues I can be sure this is OK, because on the synthetic I know within 3/4 days if it affects me]Then if I have no stomach/gut issues I can take 2 capsules 0.5...0.5 [ probably spread this amount out to begin with.. say morning/ evening 🤷‍♀️

[tattybogle in reply to birkie]

I don't feel qualified to offer an opinion on what you should do now birkie , you have lot more experience of taking things containing T3 than i do, and i have never had to deal with any gut issues.

[birkie in reply to tattybogle]

Thanks for your honesty tattybogle 🥰I suppose I will just need to get through the next 5 days crossing everything I don't have any stomach/gut issues.

But as some have mentioned 0.5grain is a small amount...although maby its OK for me....[maby]..but I reckon I'll need to increase at some point , maby see how I go then increase, then get bloods done see what my TSH ,T4 , T3 is and go from there👍

[pennyannie in reply to Brightness14]

Sorry - 1 grain NDT if Armour is 9mcg T3 + 38 mcg T4 -

so it would appear your compounded NDT is Armour -

0.50 of a grain = half a grain so around 4.50 mcg T3 + 19mcg T4:

[tattybogle in reply to Brightness14]

no , one grain is 39mcg T4 / 9mcg T3 brightness , half a grain is half that ...... 19.5 mcg T4 / 4.5mcg T3

[DippyDame in reply to Brightness14]

No....half a grain (30mcg) is 19mcg T4 and 4.5mcg T3

[birkie in reply to DippyDame]

It says on the leaflet....they provided 38mcg [T4] and 9mcg [ T3] per grain of thyroid compound natural dessicated thyroid capsule. And 0.5 being one grain........I think🙈🙈🙈🙈🙈🙈

[sparkly]

Good luck Birkie, fingers crossed this is what you need 🤞🍀

[Brightness14]

I just realised that I made a bad mistake you should in fact half the amounts that I stated. i.e. half is about 19,5 T4 and the T3 about 4.5 The same thing applies to the 19.4 T4 which still has to convert to T3.

Sorry it must be my age.

[birkie in reply to Brightness14]

😂😂😂😂😂 don't worry...I can't work it out🙈🙈 thank goodness for our site🥰🥰🥰🥰🥰🥰🥰

[pennyannie in reply to birkie]

I've replied to you above -

[Brightness14 in reply to birkie]

Exactly how would we manage without the help on the site?