Help with blood test results : Hi again Had my... - Thyroid UK

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Help with blood test results

Shenow profile image
5 Replies

Hi again

Had my bloods tested again due to low platelets and iron. Have been taking 80mg iron tablets every day for a few months now. Any insight would be appreciated. Thanks in advance! Had to translate from French so hope I’m right.

Leukocytes. 4,59 (4-10)

Red blood cells 3,93 (4-5,20)

Hemoglobin 11,7 (12-16)

Hematocrit 36,4 (37-47)

Platelets 114 (150-400)

Serum iron. 81. (50-170)

Transferrin. 2,40. (2,50-3,80)

Coefficient of saturation 24%. (15-35)

Ferritin 58,4. (10-291)

TSH. 1,610. (0.550-4,780)

T4. 15. (11,5-22,7)

T3. 4,1. (3,5-6,5)

I have hashimoto’s and take 62,5 thyroxine a day.

Thank you

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Shenow
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Lalatoot profile image
Lalatoot

Can only comment on the thyroid results. If they were mine is be needing an increase in levothyroxine.

SlowDragon profile image
SlowDragonAdministrator

How long been left on such tiny dose levothyroxine

ALWAYS test thyroid levels as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

Request dose increase in levothyroxine to 75mcg and 100mcg alternate days

Initially perhaps increasing to 75mcg daily

Retest in 6-8 weeks

ESSENTIAL to regularly retest vitamin D, folate and B12 too

How much do you weigh in kilo approx

Even if we frequently don’t start on full replacement dose, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or near full replacement dose

NICE guidelines on full replacement dose

nice.org.uk/guidance/ng145/...

1.3.6

Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.

Also here

cks.nice.org.uk/topics/hypo...

gp-update.co.uk/Latest-Upda...

Traditionally we have tended to start patients on a low dose of levothyroxine and titrate it up over a period of months. RCT evidence suggests that for the majority of patients this is not necessary and may waste resources.

For patients aged >60y or with ischaemic heart disease, start levothyroxine at 25–50μg daily and titrate up every 3 to 6 weeks as tolerated.

For ALL other patients start at full replacement dose. For most this will equate to 1.6 μg/kg/day (approximately 100μg for a 60kg woman and 125μg for a 75kg man).

If you are starting treatment for subclinical hypothyroidism, this article advises starting at a dose close to the full treatment dose on the basis that it is difficult to assess symptom response unless a therapeutic dose has been trialled.

BMJ also clear on dose required

bmj.com/content/368/bmj.m41

bestpractice.bmj.com/topics...

Guidelines are just that ....guidelines.

Some people need more some less

healthunlocked.com/thyroidu...

Shenow profile image
Shenow in reply toSlowDragon

I have been on 62.5 mg of thyroxin for years and my T4 and T3 have always been within range but I agree that the dosage seems low. When I first had thyroxin the endocrinologist increased it to 75mg but my blood test results showed that was too high. I’ll will discuss it with my GP so thanks for your comments 😀

SlowDragon profile image
SlowDragonAdministrator

Ft4 is only 31% through range Ft3 only 20% through range

Helpful calculator for working out percentage through range

chorobytarczycy.eu/kalkulator

Most people when adequately treated will have Ft3 at least 60% through range. On just levothyroxine, that often means Ft4 will need to be 60-80% through range

ALWAYS test as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

When under medicated, low vitamin levels are extremely common

Low vitamin levels tend to lower TSH

Request vitamin D, folate and B12 are tested

Ferritin is still a little too low

Looking at improving by increasing iron rich foods in diet

SlowDragon profile image
SlowDragonAdministrator

Getting thyroid levels improved might resolve constipation issues too

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