After many years of going round the NHS system with continually being told all my bloods are "within range" I have received these results today from Medichecks. Can anyone give me their opinions please as not sure if this just means I should address Vitamins or being looking to speak with my GP again.
CRP HS - 1.1 (0-5)
Ferritin - 162ug/L (13 -150)
Folate - Serum - 2.3 ug/L (2.9-14.5)
Vitamin B12 Active - 47pmol/L (25.1-165)
Vitamin D - 31 nmol/L (50-200)
TSH - 2.52 mlU/L (0.27-4.2)
Free T3 - 4.6 pmol/L (3.1-6.8)
Free Thyroxine - 12.9pmol/l (12-22)
Thyroglobulin - less than 10 (0-115)
Thyroid Peroxidase Antibodies - less than 9 (0-34)
Thank you in advance
Written by
mcgiggles
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Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)
Or Thorne Basic B is another option that contain folate, but is large capsule
IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results
If serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months, then once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.
I am not vegetarian or vegan and follow as normal diet, where possible.
I had my gallbladder removed just over 2 years ago around the time I last posted results via this forum and since then health has deteriorated month on month. I've had numerous ultrasounds and endoscopies and been told to try a Low Fodmap diet but that didn't work either so I dip in and out of excluding gluten, dairy and red meat (typically don't eat very much red meat as it always seems to cause stomach problems) and basically been told I have IBS.
I have an ever extending list of symptoms which was pointing me toward Hypothyroidism but just can't seem to get a diagnosis (skin break-outs, butterfly bruise like rash around thyroid, sensitive to touch thyroid, pins and needs in feet, tightness around left ankle, unexplained weight gain, etc etc)
I think I possibly need to self-supplement and then test again in the hope I can finally get some form of diagnosis.
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Consider ultrasound scan of thyroid
£150 if GP won’t
Lots of private companies offer
20% of Hashimoto's patients never have raised antibodies
This is an inflammation marker and is nice and low so no problem there.
Ferritin - 162ug/L (13 -150)
A bit over range, ferritin is recommended to be half way through range and some experts say that the optimal ferritin level for thyroid function is between 90-110 ng/ml (which is the same as ug/L). Do you take iron tablets, or maybe eat a lot of meat, liver, etc.
Folate - Serum - 2.3 ug/L (2.9-14.5)
This is folate deficiency and you should see your GP about this and folic acid may be prescribed. See
If you do then list them to discuss with your GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results.
Vitamin D - 31 nmol/L (50-200)
This is just barely above Vit D deficiency and you need to see your GP and hopefully will be prescribed loading doses of D3. See NICE treatment summary for Vit D deficiency: cks.nice.org.uk/vitamin-d-d...
(click on Management > Scenario:Management)
"Treat for vitamin D deficiency if serum 25-hydroxyvitamin D (25[OH]D) levels are less than 25 nmol/L.
For the treatment of vitamin D deficiency, the recommended treatment is based on fixed loading doses of vitamin D (up to a total of about 300,000 international units [IU]) given either as weekly or daily split doses, followed by lifelong maintenance treatment of about 800 IU a day. Higher doses of up to 2000 IU a day, occasionally up to 4000 IU a day, may be used for certain groups of people, for example those with malabsorption disorders.
* Several treatment regimens are available, including 50,000 IU once a week for 6 weeks (300,000 IU in total), 20,000 IU twice a week for 7 weeks (280,000 IU in total), or 4000 IU daily for 10 weeks (280,000 IU in total)."
In some areas deficiency is classed as <30, in others it's <25. If your GP wont give loading doses, not to worry, just get your own D3 supplement (which might be best anyway) and follow the dosing regime above.
Once the loading doses have been completed you will need a reduced amount so you should make sure that you are retested after you have finished the loading doses so that you know how much you should then take going forward. Most doctors, if they continue prescribing, only give 800iu daily which isn't enough. If GP wont retest then do this privately (link below) and post your new result at the time for members to suggest a new dose to bring your level up to what's recommended by the Vit D Council/the Vit D Society - which is 100-150nmol/L - and then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3.
D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.
My suggestion for a good quality, clean D3 supplement with no excipients is Doctor's Best D3 softgels, they contain only D3 and extra virgin olive oil to aid absorption.
For Vit K2-MK7 I like Vitabay or Vegavero brands.
Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.
A normal healthy person would have TSH no higher than 2, often around 1, with FT4 around mid-range-ish. As none of us are tested for a baseline in health then we don't know what's normal for us; however, your FT4 is very close to the bottom of the range that I believe you're well on your way to hypothyroidism but don't yet have the results for your GP to diagnose this. For Primary Hypothyroidism diagnosis is made when TSH goes over 10, if raised antibodies are present then autoimmune thyroid disease can be diagnosed when TSH goes over range.
Thyroglobulin - less than 10 (0-115)
Thyroid Peroxidase Antibodies - less than 9 (0-34)
Your antibodies are low so currently don't suggest autoimmune thyroid disease (known to patients as Hashimoto's). However, one negative result doesn't rule Hashi's out, and it's possible to have Hashi's without raised antibodies.
I think the first thing to do is optimise your nutrient levels as outlined above. The levels to aim for are:
Vit D - 100-150nmol/L
B12 - top of range for Total B12 (which is what is usually done with an NHS test), or 100+ with Active B12 would be a good level
Folate - at least half way through range
Once your nutrient levels are optimal you need to maintain those levels so you don't stop supplementing you just reduce to a maintenance dose. Also have a look again at your thyroid levels and see how they are at that time.
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