High Ferritin Levels

[laceysmum]

Good Afternoon

Just wondering if someone could look my latest results and give some idea of the interpretation. Thank you

Biochemistry

hs-CRP 2.74 <5.0 mg/L

Ferritin H 220.0 13 - 150 ug/L

Magnesium 0.89 0.66 - 0.99 mmol/L

Hormones

Cortisol (Random) 369.0

Thyroid Function

TSH 0.62 0.27 - 4.20 mIU/L

T4 Total 117. 0 66 -181 nmol/L

Free T4 20.7 12.0 - 22.0 pmol/L

Free T3 4.18 3.1 - 6.8 pmol/L

Immunology

Anti-Thyroidperoxidase abs 14 <34 kIU/L

Anti-Thyroglobulin Abs 13 <115 kIU/L

Vitamins

Vitamin D (25 OH) 73 50 - 175 nmol/L

Vitamin B12 448 Deficient <145 pmol/L

Insufficient 145 - 300

Consider reducing dose >569

Serum Folate 15.40 8.83 - 60.8 nmol/L

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[SlowDragon Administrator]

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healthunlocked.com/thyroidu...

What medication are you prescribed? Levothyroxine? What dose? What brand?

What vitamin supplements are you currently taking

Was test done as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

[laceysmum in reply to SlowDragon]

Hi.

125 made up of 100 accord and 25 teva. I stopped b complex about a week before test and took the test at 7am 24 hours after last thyroxine.

Thankyou

[SlowDragon Administrator in reply to laceysmum]

So Ft4 is 87% through range

But Ft3 is only 30% through range

Helpful calculator for working out percentage through range

chorobytarczycy.eu/kalkulator

You’re a poor converter

Vitamin D might be better nearer 100nmol

Are you currently taking any vitamin D, magnesium, vitamin K2 mk7, selenium or zinc?

You may need to consider reducing levothyroxine slightly and adding small dose of T3 alongside

Email Dionne at Thyroid UK for list of recommend thyroid specialist endocrinologists who will prescribe T3

[e-mail]

Many people don’t tolerate Teva brand levothyroxine. Have you noticed any reaction?

[laceysmum in reply to SlowDragon]

Thanks very much for your advice. I will contact gp re full iron panel and all other suggestions. I do also have teva candesartan 16mg but I dont know if any problems with this. Problem is they quite frequently change the brands so I will ask for the same brand.

[SlowDragon Administrator in reply to laceysmum]

Many people find Levothyroxine brands are not interchangeable.

Once you find a brand that suits you, best to make sure to only get that one at each prescription. Watch out for brand change when dose is increased or at repeat prescription.

Many patients do NOT get on well with Teva brand of Levothyroxine. Teva contains mannitol as a filler, which seems to be possible cause of problems. Teva is the only brand that makes 75mcg tablet. So if avoiding Teva for 75mcg dose ask for 25mcg to add to 50mcg or just extra 50mcg tablets to cut in half

Teva and Aristo are the only lactose free tablets

healthunlocked.com/thyroidu...

Teva poll

healthunlocked.com/thyroidu...

academic.oup.com/jcem/artic...

Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).

Levothyroxine is an extremely fussy hormone and should always be taken on an empty stomach and then nothing apart from water for at least an hour after

Many people take Levothyroxine soon after waking, but it may be more convenient and perhaps more effective taken at bedtime

verywellhealth.com/best-tim...

No other medication or supplements at same as Levothyroxine, leave at least 2 hour gap. Some like iron, calcium, magnesium, HRT, omeprazole or vitamin D should be four hours away

(Time gap doesn't apply to Vitamin D mouth spray)

[laceysmum in reply to SlowDragon]

Hi . Sorry for being slow but just wondering how 4.8pmol is a third of the range of 3.1 -6.8 pmol. Thankyou

[helvella in reply to laceysmum]

To work out how far through a reference interval (range) a result is, we need to do the following:

Find out how big the interval is. That is, how far it is from the bottom to the top of the interval.

If the reference interval were 3.1 to 6.8, you would subtract 3.1 from 6.8 giving 3.7.

Then work out how far from the bottom of the interval your result is. If your result were 4.8, then subtract 3.7 from 4.8 giving 1.1.

Now what percentage is your result (1.1 up from the bottom) of the interval (3.7)? Divide 1.1 by 3.7. Which gives 0.297…. And multiply that by 100 to convert it to a percentage. 29.7 – near enough, 30%. Which is almost a third.

[laceysmum in reply to helvella]

Oh thats clearer , Thank you very much.

[SlowDragon Administrator]

High ferritin is common with Hashimoto’s...due to inflammation

Other possible cause can be non Alcoholic fatty liver disease

Ask GP for full iron panel test to see if iron is also high

Links about iron and ferritin

irondisorders.org/Websites/...

High ferritin and hemeachromatosis

healthunlocked.com/thyroidu...

Post about high ferritin

healthunlocked.com/thyroidu...

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...