Can you help with my daughter's results please? - Thyroid UK

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Can you help with my daughter's results please?

dwsmith profile image
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Ferritin 8.9. (13 - 150),

Folate. 10.10. (8.83 - 60.8),

TSH. 1.96. (0.27 - 4.20)

Total T4. 69.3. (66 - 181)

Free T4 11.4. (12 - 22)

Free T3 5.05. (3.1 - 6.8)

Vitamin B12 and D3 are in range. She is experiencing symptoms but iv been advised to go down nutritional route as opposed to hormone, can you share your knowledge please, I would really appreciate it, thank you.

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dwsmith

Can I also add that the antibodies tests are negative, thank you, Dwsmith

SeasideSusie profile image
SeasideSusieRemembering

dwsmith

She is experiencing symptoms but iv been advised to go down nutritional route as opposed to hormone,

Who advised that?

Below range FT4 with a normal (or low or slightly elevated) TSH suggests Central Hypothyroidism, which is where the problem lies with the pituitary or hypothalamus rather than the thyroid. The feedback loop isn't working properly and the TSH isn't signalling the thyroid to make hormone - hence the low FT4.

Ferritin 8.9. (13 - 150),

This is dire. Low ferritin can suggest iron deficiency anaemia. She needs to make an appointment with her GP. She needs to have an iron panel and a full blood count, these tests will show if she has iron deficiency or iron deficiency anaemia.

Symptoms of low ferritin include:

◾Weakness

◾Fatigue

◾Difficulty concentrating

◾Poor work productivity

◾Cold hands and feet

◾Poor short-term memory

◾Difficulty remembering names

◾Dizziness

◾Pounding in the ears

◾Shortness of breath

◾Brittle nails

◾Headaches

◾Restless legs

Folate. 10.10. (8.83 - 60.8),

This is low in range, folate is recommended to be at least half way through range.

Vitamin B12 and D3 are in range.

What are the actual results. "In range" means exactly that, but it's where in range the result falls that is important. Is this a Medichecks test? If so then Active B12 needs to be over 70, preferably around the 100 mark. If it's a Blue Horizon test then Total B12 needs to be over 412pmol/L at the very least, preferably around 660+

dwsmith profile image
dwsmith in reply to SeasideSusie

Hi SeasideSusie,

these blood tests were done by Blue Horizon, Vitamin D (25 OH) - 58 (30 - 175)

B12 - 358 (145 - 369). Is the treatment the same for Iron deficiency and Iron deficiency Anemia? She is taking Hemaplex now, with Central Hypothyroidism is it the same treatment as Hypothyroidism? with her T3 being in normal range, what do you think?

Marz profile image
Marz in reply to dwsmith

I have read that when the thyroid is struggling due to lack of TSH or other causes - it secretes more T3 to keep things going in the body. T3 is the active hormone.

Vitamin deficiencies v thyroid issues - chicken or egg. I would hate to say. 😎

SeasideSusie profile image
SeasideSusieRemembering in reply to dwsmith

dwsmith

Vitamin D (25 OH) - 58 (30 - 175)

The Vit D Council recommends a level of 125nmol/L and the Vit D Society recommends a level of 100-150nmol/L. To achieve the recommended level from her current level the Vit D Council suggests supplementing with 4,000iu D3 daily.

Retest after 3 months.

Once she has reached the recommended level then she'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. She can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:

vitamindtest.org.uk/

Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3 as recommended by the Vit D Council.

D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.

Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.

Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.

naturalnews.com/046401_magn...

drjockers.com/best-magnesiu...

afibbers.org/magnesium.html

B12 - 358 (145 - 369)pmol/L = 485.09pg/ml

According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

A good, bioavailable B Complex will help raise her level, eg Thorne Basic B or Igennus Super B.

She is taking Hemaplex now

Is this what she's taking?

amazon.co.uk/Natures-Plus-H...

If so it's a multivitamin with only 43mg iron. If she has iron deficiency/iron deficiency anaemia she will be prescribed 3 x ferrous fumarate tablets, each of which contain 65mg elemental iron. So the amount of iron in 1 capsule of Hemaplex is not enough for iron deficiency/iron deficiency anaemia. She needs to see her GP.

Another thing about that supplement, if she is hoping the other active ingredients will help, they wont because the iron will affect their absorption. Iron needs to be taken 2 hours away from other supplements.

Is the treatment the same for Iron deficiency and Iron deficiency Anemia?

Iron is complicated and I'm not au fait with treatment. Anaemia is caused by lack of Haemoglobin. Iron Deficiency is caused by lack of Iron. Iron Deficiency with Anaemia is caused by both a lack of Iron AND a lack of Haemoglobin.

with Central Hypothyroidism is it the same treatment as Hypothyroidism?

I'm not medically qualified and not an expert on Central Hypthyroidism (and neither are many thyroid specialists) but it's likely that the pituitary and hypothalamus will need to be checked (scans?). I think treatment is the same as Primary Hypothyroidism but when tests are carried out the TSH needs to be ignored (because the signal doesn't work properly) and FT4/FT3 should be used to base dose of levothyroxine on.

with her T3 being in normal range

Because T3 is the active hormone that every cell in our bodies need, the body will do it's utmost to push out as much T3 as possible but eventually the FT3 will very likely lower as well.

She needs to see her GP. She needs to push for investigation into Central Hypothyroidism, she should not be fobbed off, it's not as common as Primary Hypothyroidism, her GP may not have heard of it and he should look for a thyroid specialist - not any old endocrinologist because most of them are diabetes specialists who know very little about the thyroid anyway, it must be a thyroid specialist.

Here is some information I have saved about Central Hypothyroidism. Her GP can look at BMJ Best Practice for information - here is something she can read without needing to be subscribed (you can only read the Summary but make sure she clicks "Read More" as well:

bestpractice.bmj.com/topics...

and another article which explains it:

ncbi.nlm.nih.gov/pmc/articl...

and another here:

endocrinologyadvisor.com/ho...

She could do some more research, print out anything that may help and show her GP.

She must also push for further investigation into her dire ferritin level and ask for an iron panel and full blood count.

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