Help with blood test results please: Hi there... - Thyroid UK

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Help with blood test results please

KazLS profile image
8 Replies

Hi there, would it be possible to have some advice on my results please? I followed previous advice (thank you) and did the blood test 1st thing in the morning before taking my morning meds. My current dose of levothyroxine is 75mcg which I have been on since first getting diagnosed with Hashis 2 years ago.

Results

CRP HS 1.27 <5

Ferritin 127 13-150

Folate-serum 14.08 >3.89

Vit B12 active 100 >37.5

Vitamin D 40.3 50-175

TSH .668 0.27- 4.2

Free T3 3.14 3.1-6.8

Free Thyroxine 16.7 12 - 22

Thyroglobulin Antibodies 2287 <115

Thyroid Peroxidase Antibodies >600 <34

The suggestion from the medicheck GP was to supplement with Vit D and to change my diet for the antibodies. His suggested list of foods to eliminate or avoid was very long!I have already asked my GP for a referral to a dietician as I have high cholesterol and I do not want to continue on statins.

Any help or advice would be very much appreciated:-)

Thank you!

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KazLS
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8 Replies
Aslangal profile image
Aslangal

Someone will be along soon who is very experienced in interpreting blood results I’m sure. I don’t know enough to help. Your antibodies are very high though. Hang in there. 😉

KazLS profile image
KazLS in reply to Aslangal

Thank you Lyn:-)

SeasideSusie profile image
SeasideSusieRemembering

KazLS

CRP HS 1.27 <5 - this is an inflammation marker, low in range so it's good.

Ferritin 127 13-150 - ferritin is recommended to be half way through range, so about 83ish with that range. Do you supplement?

Folate-serum 14.08 >3.89 - folate is recommended to be at least half way through range, but as there is not a complete range with a lower and upper level, then a result in double figures is OK.

Vit B12 active 100 >37.5 - this is a good result.

Vitamin D 40.3 50-175

This is low. The Vit D Council recommends a level of 125nmol/L and the Vit D Society recommends a level of 100-150nmol/L. To reach the recommended level from your current level, based on the Vit D Council's suggestions you could supplement with 5,000iu D3 daily.

Retest after 3 months.

As you have Hashi's, you might want to consider using an oral spray, eg BetterYou, as this is absorbed through the mucous membranes in the oral cavity and bypasses the stomach. Some Hashi's patients have also done well on an oil base softgel, eg Doctor's Best.

Once you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:

vitamindtest.org.uk/

Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3 as recommended by the Vit D Council

D3 aids absorption of calcium from food and Vit K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.

D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking D3 as tablets/capsules/softgels, no necessity if using an oral spray.

Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.

Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking magnesium as tablets/capsules, no necessity if using topical forms of magnesium.

naturalnews.com/046401_magn...

drjockers.com/best-magnesiu...

afibbers.org/magnesium.html

Thyroglobulin Antibodies 2287 <115

Thyroid Peroxidase Antibodies >600 <34

Raised antibodies confirm autoimmune thyroid disease aka Hashimoto's which you already know about, and SlowDragon gave you advice about this in reply to your previous post here:

healthunlocked.com/thyroidu...

Supplementing with selenium l-selenomethionine 200mcg daily is said to help reduce the antibodies, as can keeping TSH suppressed.

TSH .668 0.27- 4.2

Free Thyroxine 16.7 12 - 22

Free T3 3.14 3.1-6.8

Your FT4 is 47% through range and your FT3 is only 1.08% through range which shows poor T4:T3 conversion so adding some T3 to your levo is indicated.

KazLS profile image
KazLS in reply to SeasideSusie

Thank you SeasideSusie:-). No I don't currently take any supplements other than GOPO (Rosehip) for arthritis. I will definitely start supplementing from now on. As my conversion is not good and I know the issues around T3- is it worth taking the DIO2 test?

Many thanks for you advice

SeasideSusie profile image
SeasideSusieRemembering in reply to KazLS

is it worth taking the DIO2 test?

You already know your conversion is poor and if the DIO2 test shows a gene mutation to this effect then to get T3 on the NHS you will need to find an endo who accepts this test and is willing to prescribe - not the easiest job I'm afraid.

KazLS profile image
KazLS in reply to SeasideSusie

No I figured as much SeasideSusie:-(. It might be worth a shot though as I think the only way I will be able to get my cholesterol down is via optimum T3 levels. l will start supplementing, see a dietician and take the DIO2 test and then take it from there...…..

Really appreciate the help and advice!

SlowDragon profile image
SlowDragonAdministrator

Your Ft4 is only 47% through range

And as SeasideSusie says, conversion is terrible with Ft3 at just 1%

You need dose increase in levothyroxine....see if you can persuade GP to increase dose to 100mcg as a “trial”

Your antibodies are very high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone

Obviously you need good vitamin D.

GP will only prescribe to bring levels to 50nmol.

But improving to around 80nmol or 100nmol may be better

ncbi.nlm.nih.gov/pubmed/218...

vitamindsociety.org/pdf/Vit...

Once you vitamin D Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function. There’s a version made that also contains vitamin K2 Mk7

It’s trial and error what dose we need, with hashimoto’s we frequently need higher dose than average

ouh.nhs.uk/osteoporosis/use...

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten intolerance. Second most common is lactose intolerance

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find strictly gluten free diet reduces symptoms, sometimes significantly. Either due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying strictly gluten free diet for 3-6 months

If no noticeable improvement, reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

High cholesterol is linked to hypothyroidism being under medicated and statins are not recommended when hypothyroid

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

Dose of levothyroxine is likely to need to be increased slowly until on 1.6mcg levothyroxine per kilo of your weight

Post re how to get dose increase

healthunlocked.com/thyroidu....

gp-update.co.uk/Latest-Upda...

How to get TSH as high as possible

thyroidpatients.ca/2020/01/...

KazLS profile image
KazLS in reply to SlowDragon

Thank you SlowDragon, that is so helpful. I am going to try gluton free for 6 months but will get a coeliac test - I did go GF for about 10 days 4 weeks ago but realised that I should have had the test first. Do you think a 4 week period of eating Gluton again will be enough to test for Coeliac now?

I think my GP will be reluctant to increase levo based on my review in oct when she suggested reducing it based my low TSH level but I will push for it!Based on my current weight 46kg the calculation of 1.6 x 46 means my current dose is about right, my concern is that if I increase my dose I will lose weight - which has been a bit of an issue since starting treatment.I am a bit of a loss knowing how to increase my T3 (assuming I cant get a precription for T3) and not lose weight by increasing my throxine meds- any advice would be really appreciated!

Many thanks for all your help-I am so grateful for all the excellent advice and support on this forum!

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