Medichecks blood tests back. Any input and or advice please?

[ZenBear]

Hi guys,

finally had the ultimate performance blood test done with medichecks, which is fairly extensive. Almost everything has come back as normal, which is great but also highly frustrating as there's still no rhyme or reason as to why I have all these symptoms and why my reflexologist is convinced I have a some kind of thyroid issue. I'm including applicable test results and anything that was deemed low/high but still within normal range. Please advise.

Here's previous results.

July 2019 taken 10:51AM Fasting

.........................................................Result....................................reference range

Haemoglobin .................................127........................................115 - 165 g/L

Haematocrit....................................0.385....................................0.36 - 0.47 ratio

white cell count .............................4.0..........................................4.0 - 11.0 10^9/L

Neutrophil count...........................1.34........................................2.0 - 7.5 10^9/L

Lymphocyte count.........................2.11.......................................1.5 - 4.0 10^9/L

Vitamin B12 - ..................................309 .......................................180 - 2000 ng/L

Serum folate.....................................18.5........................................2.8 - 20 ug/L

TSH.......................................................0.93.......................................0.2 - 4.5 mU/L

FT4.........................................................13..........................................9 - 21 pmol/L

CRP ......... not recorded on my current printout but told it was high

******

September 2019 taken 13:35PM non- fasting

Haemoglobin .................................114........................................115 - 165 g/L

Haematocrit....................................0.339....................................0.36 - 0.47 ratio

white cell count .............................6.3..........................................4.0 - 11.0 10^9/L

Neutrophil count...........................2.65........................................2.0 - 7.5 10^9/L

Lymphocyte count.........................2.80.......................................1.5 - 4.0 10^9/L

Vitamin B12 - ..................................333 .......................................180 - 2000 ng/L

Serum folate.....................................8.5........................................2.8 - 20 ug/L

TSH.......................................................2.1.......................................0.2 - 4.5 mU/L

FT4.........................................................12..........................................9 - 21 pmol/L

CRP.......................................................6...............................................0 - 5 mg/L

********

October 2019 Taken 09:35AM Fasting (Medichecks test)

MCHC..................................................347..........................................300 - 350 g/L

Haemoglobin .....................................127........................................120 - 160 g/L

HAEMATOCRIT...................................0.366......................................0.35 - 0.47 L/L

WHITE CELL COUNT...........................3.15.......................................3 - 10 10^9/L

NEUTROPHILS.....................................0.84.......................................2 - 7.5 10^9/L

LYMPHOCYTES....................................1.91.......................................1.2 - 3.65 10^9/L

MONOCYTES.......................................0.24.......................................0.2 - 1 10^9/L

URIC ACID............................................355.......................................140 - 360 umol/L

CREATINE KINASE..............................256........................................26 - 192 IU/L

FERRITIN..............................................89.8.......................................13 - 150 ug/L

TRANSFERRIN SATURATION.............23.03......................................% 20 - 50

VITAMIN B12 - ACTIVE.......................102........................................> 37.5 pmol/L

VITAMIN D..........................................52.6.......................................50 - 175nmol/L

TSH......................................................0.592.....................................0.27 - 4.2mIU/L

FREE T3................................................4.63.......................................3.1 - 6.8pmol/L

FREE THYROXINE...............................18.2........................................12 - 22 pmol/L

TgAb....................................................12.2........................................< 115kIU/L

TPOAb.................................................9.87........................................< 34kIU/L

CORTISOL............................................222.........................................166 - 507 nmol/L

TESTOSTERONE..................................1.86........................................0.29 - 1.67 nmol/L

FREE TESTOSTERONE - CALC.............0.03.......................................0.003 - 0.03 nmol/L

SHBG....................................................41.8........................................32.4 - 128 nmol/L

[SlowDragon Administrator]

High testosterone and high SHBG suggest PCOS

PCOS and Hashimoto's can be linked

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

Your TSH and FT4 levels are variable which also suggests Hashimoto's

Low vitamin D

GP will only prescribe to bring vitamin D up to 50nmol. Aiming to improve by self supplementing to at least 80nmol and around 100nmol may be better .

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Retesting twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is good as avoids poor gut function.

It's trial and error what dose each person needs. Frequently with Hashimoto's we need higher dose than average

Local CCG guidelines

clinox.info/clinical-suppor...

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Suggest you read up on PCOS

nhs.uk/conditions/polycysti...

thepcosnutritionist.com/res...

verywellhealth.com/things-w...

[ZenBear in reply to SlowDragon]

Hi, thanks for that reply. I definitely have PCOS. Diagnosed in 2011, had ultrasounds etc which confirm. Told cysts were average size, not exceptionally big, but definitely apparent. 🤷🏾‍♀️ So yes, not surprised at those hormone levels.

I’m still fairly convinced that there’s something going on with my thyroid also however. How do I investigate whether or not I have Hashimoto’s more? When I first started to look into thyroid problems, this is the one that I kept coming back to with regard to my symptoms and potential issues.

[SlowDragon Administrator in reply to ZenBear]

Are you addressing PCOS with diet?

Your thyroid antibodies appear to be negative

20% of Hashimoto's patients never have raised antibodies. Getting a thyroid ultrasound might reveal Thyroid damage

healthunlocked.com/thyroidu...

[ZenBear in reply to SlowDragon]

Not specifically changing diet for PCOS, but I am actively trying to lose weight and I generally eat healthily anyway, so I think this will help.

How would I go about getting an ultrasound done of my thyroid? I’m certain my GP won’t refer me for this, they don’t even want to do blood tests usually.

[SlowDragon Administrator in reply to ZenBear]

Email Dionne at Thyroid Uk for list of recommended thyroid specialist endocrinologists

Private ultrasound scan of thyroid costs about £300-400

thyroiduk.org.uk/tuk/About_...

Trying strictly gluten free diet perhaps good next step

[ZenBear in reply to SlowDragon]

Omg! I couldn’t be any more frustrated if I tried. Just saw my GP (not my usual one) and she basically said I was talking nonsense, she’d never heard of Medichecks and had doubts whether their tests are viable as they ‘don’t use the same labs as the NHS’ (how does she know this by the way?). And also that even if my thyroid tests are consistently varying, it’s all still within normal range so there’s absolutely nothing wrong. She agreed to check my white cells levels and redo a blood test for my neutrophils and a random cortisol (is that even helpful is it’s my AM levels that we’re low-ish?). It’s literally like talking to a brick wall. It’s so SO frustrating. She looks at me so pityingly like I’m a mad person that needs appeasing and then...to add insult to injury, she was like “jus to put you at ease let’s check your blood pressure”...whaaaaat!?!?! I’m beyond furious. Don’t know what I was expecting but I’m appalled to say the least.

[SlowDragon Administrator in reply to ZenBear]

GP probably unaware of the link

25% of PCOS patients have Hashimoto's

thepcosnutritionist.com/res...

endocrineweb.com/news/thyro...

Diet and PCOS

medicalnewstoday.com/articl...

[suztango]

Your cortisol level at 9am is low. My Result of 302 was deemed ‘borderline low ‘ by my GP. Yours is lower than mine. Every cell needs T3 + cortisol to make energy.

[ZenBear in reply to suztango]

Ok, but it falls within the reference rages so how do I argue that it’s low? I’ve made an appointment with my GP to discuss some of these results. Looking at the symptoms for low cortisol, I literally suffer from every single one of them. But again...it’s like talking to a brick wall when the blood tests come back within reference range. Any tips?

[suztango in reply to ZenBear]

According to the NHS (well my area anyway), low cortisol such as yours would show up as ‘borderline low’. The doctor would have to talk about it with you.

The Medichecks ranges didn’t bother to put in the borderline low range. They’ve just said if you’re not Addisons or Cushings then you’re normal.

This is what came back on my NHS cortisol blood test:

“Plasma cortisol level 302 nmol/L

To exclude hypoadrenalism, samples for cortisol should

ideally be collected between 8-10 am.

Hypoadrenalism is excluded if a basal cortisol or post

short Synacthen test cortisol concentration exceeds:

459 nmol/L in males.

455 nmol/L in females not on oral contraceptive pill

604 nmol/L in females taking oral contraceptive pill

Random cortisol is an inappropriate test for Cushing's.

Suggest 11 pm salivary cortisol, 24-hour urinary free

cortisol or low dose dexamethasone suppression test.”

Ie recommends further investigation.

I think you should do a 4 pt saliva Cortisol test next. It will tell you your cortisol levels throughout the day. People here don’t recommend the Medichecks one as it doesn’t include DHEA. Regenerus does one that includes DHEA. I ordered one for myself 2 days ago.