Peeling Skin on Hands: I wonder if anyone else... - Thyroid UK

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Peeling Skin on Hands

Milkmaid123 profile image
10 Replies

I wonder if anyone else has peeling skin on their hands? Or if it is anything to do with my thyroid issues at all?

I am still on a block and replace regime. Currently 40mg Carbimazole daily and 100mcg Levothyroxine. I have been on block and replace for 20 months now and they tweak the Levo up or down 25mcg depending on the TSH and T4 result.

Some of the time I feel ok (ish!) and other times I can feel either hypo or hyper - I haven’t quite worked out any one reason for the changes! But I’m working on that.

I am also on Vit D and calcium. Prescribed by Endocrinologist.

From my latest Blue Horizon results (attached) it looks to me like I need folate?

I have NHS blood tests every 6 weeks, but they only test TSH and T4 - the last was at the same time as the attached.

The letter came from Endo to say results were in the normal range so continue with block and replace at present dose.

I would really appreciate your comments on my peeling hands and anything else you consider I should be doing.

Thank you.

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Milkmaid123
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10 Replies
greygoose profile image
greygoose

It's not a symptom I've ever had myself, but it would appear that lots of hypos have peeling hands, yes. If you do a search on this page, you'll probably come up with a lot of other posts complaining about the same thing.

And, you are hypo, despite your good TSH. Your FT3 is very low. Did you ever find out if you really do have Grave's? If they ever tested your TSI or TRAB? Or if you really have Hashi's, and they're treating you for the wrong disease?

SlowDragon profile image
SlowDragonAdministrator

Yes, personally I think peeling skin on hands may be linked to food intolerances....obviously extremely common with Hashimoto's

Your private tests from year ago showed you had low vitamin D and low folate

healthunlocked.com/thyroidu...

Vitamin D is now just about ok....but around 100nmol may be better

Folate still low

B12 very low too

Supplementing a good quality daily vitamin B complex, one with folate in not folic acid may be beneficial.

chriskresser.com/folate-vs-...

B vitamins best taken in the morning after breakfast

Recommended brands on here are Igennus Super B complex. (Often only need one tablet per day, not two. Certainly only start with one tablet per day after breakfast. Retesting levels in 6-8 weeks ).

Or Jarrow B-right is popular choice, but is large capsule

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

If you have low B12 symptoms.....then you may need sublingual B12 as well for few months

b12deficiency.info/signs-an...

Low vitamin D and low B vitamins both often together...and common with Hashimoto's - as explained here

drgominak.com/sleep/vitamin...

Are you on strictly gluten free diet?

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Might be worth testing to see if you ever had Graves' disease....results seem to suggest only Hashimoto's

But you can have both

Private testing for suspected Graves - TSI or TRab antibodies

medichecks.com/thyroid-func...

Your results suggest you need small dose increase in Levothyroxine

asiatic profile image
asiatic

I am no expert only an " informed " patient with Graves who likes to follow other patients with this disease and a couple of things confuse me about your treatment. Why is your TSH so high mine was always suppressed or low ? Why are your fT4/FT3 not higher in range ? Could it be you are on too high a dose of Carbimazole and would benefit from a reduction . Perhaps someone could answer ??

Milkmaid123 profile image
Milkmaid123

Thank you for your quick replies.

I asked whether I had been tested for Graves, and apparently I was, but Endo didn’t have the results to give me.

I haven’t been officially diagnosed with Hashimoto’s yet.

Unfortunately I have only seen a succession of locum Endos, who all seem to have differing opinions about what should be done.....apparently a permanent consultant is due to start soon, so hopefully a future way forward can be planned for me.

I will go through your suggestions SlowDragon.

Asiatic, I am on block and replace regime at the moment. So the carbimazole is at a dose to ‘block’ my thyroid and then, technically, the Levo should be at a dose to keep me well. But, tweaking the Levo up and down doesn’t seem to stabilise me.

Thank you all again for your replies, I really appreciate them.

SlowDragon profile image
SlowDragonAdministrator in reply to Milkmaid123

You are legally entitled to printed copies of your blood test results and ranges

Write/email endocrinologist for copies of results of TSI or TRab Graves antibodies test

If you can't get copies then request test is redone at next appointment

Or test privately

Valarian profile image
Valarian in reply to SlowDragon

the problem with getting TSI/TRAb tested at this stage is that it won't tell Milkmaid123 what they were when she was first diagnosed. Her antibodies may have been positive initaiily but after so many months of carbimazole they may now be sigificantly lower, or even return a negative result.

Milkmaid123 - do you know what your initial FT3/FT3 and TSH were ? How long have your results been within range ?

I'm not sure that it's possible to tell what your natural thyroid levels would be while you are taking such a high dose of carbimazole, combined with levo. For me, that has always seemed to be one of the downsides of the block and replace approach: once your results are within range, you can't really tell whether you are likely to achieve remission or not until you stop the medication, so it's a step into the unknown.

Assuming you did have Graves', it's a positive sign that your TSH has recovered. It can remain suppressed for many months. During active Graves', the antibodies effectively take over the role of TSH, signalling the thyroid to create more hormone, while TSH remains suppressed. Unlike TSH, the antibodies don't switch off when sufficient thyroid hormone has been produced.

asiatic profile image
asiatic

I too am on block and replace but to get my sweet spot it was not only necessary to adjust levo but also Carbimazole. I must have had a dozen adjustments and am now on 10mg Carb / 50mcg Levo. I suspect your Carbimazole is too high and as it can have nasty side effects you want to be on the lowest effective dose. Most endos arent prepared to closely monitor a patient as it is time consuming

JumpJiving profile image
JumpJiving

I am hypo, and have taken levothyroxine for years. I am also allergic to lactose. The consequence of eating something containing lactose depends on the quantity. The very slightest trace causes my skin (particularly on the face and scalp), eyes, nasal passages etc to dry out to the extent that the next morning my face in particular is like a snake shedding its skin, I will be seriously bunged up, and I cannot focus my eyes until I have put in drops. However, that drying has not previously been a problem with my hands. This year, I started taking NDT (NP Thyroid, which is lactose-free). Since then, my hands have been peeling, on the inside of the hand just below the gap between fingers. I've only ever had anything similar in the depths of winter, when being outside in winter air multiple times per day (walking dog) resulted in cracking (rather than peeling) between the fingers (not just below the gap). It may be coincidence of timing that the peeling has started since taking NDT, but my suspicion is that there is a connection. I have had a few lactose reactions in the same time period too (I blame cross contamination in crisps - one of those "made in a factory that also handles milk" cop outs that may actually be true this time), but the peeling hands has been a regular thing since taking NDT, not just when I have had a lactose reaction. Do I have an explanation as to why NDT might trigger this? Nope, afraid not.

(and yes I do dry my hands properly after washing, and yes I do moisturise).

LuluCops profile image
LuluCops

I suffer badly with peeling hands, I don’t know whether it’s my thyroid or vitamin deficiencies but they were very bad and I tried everything going. In the end it was a pharmacist in Boots that recommended a product to me, it is expensive at £10.99 but you can get it on prescription, it’s the only thing that’s worked so I now get it on prescription. It’s called Dermol 500 lotion, it is an antimicrobial emollient and moisturiser and can be used as a soap substitute too. I find it excellent!

ling profile image
ling

How is your toxic multinodular goitre being monitored?

I guess this was why u were originally put on carbimazole.

Have they grown bigger? Has the condition progressed?

It's interesting after levo was subsequently added, that you started to feel more normal.

Could this be an indication of your Hashimoto's status since both your TPO and TG antibodies remain high?

Would dealing with the toxic multinodular goitre, and leaving only Hashimoto's to contend with, leave you more stable?

Carbimazole can then be withdrawn, and its a matter of seeing the Hashimoto's run its course.

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