New results ! HELP Please.

[Breena]

Test 9th jan 19. 5.30 pm non fasting my surgery now only take blood PM

Had telephonic appointment . with a new doctor

Serum folate 11ug/L 2.00 - 17.00 ug/L

Vit D serum total 25-OH vit D level 131 nmol/L 75.00 -200.00 nmol/L

Plasma vit B12 543 ng/L 200.00 - 900.00ng/L

TSH 0.22 mu/L 0.35 - 5.00 mu/L

Free T4 22.2 pmoI/L 9.00 - 24.00 pmoI/L

Free T3 4.2 pmoI/L 3,50 - 6.50 pmoI/L

Haemoglobin A1c level 43 mmoI/moI 20.00 - 41.00mmoI/moL

Thyroxine dose changed from 100 / 75 alt days

To 75 mg a day as Dr said TSH was to low and to retest in 3 Months

also haemoglobin was heading towards Diabetic Although I am slim and eat a very healthy diet.

Still not feeling well nothing much has changed since my last post .Any help appreciated.

Having medicheck thyroid & ultravit on monday.

[SeasideSusie Remembering]

Breena

Serum folate 11ug/L 2.00 - 17.00 ug/L

This is fine, folate is recommended to be at least half way through range.

Vit D serum total 25-OH vit D level 131 nmol/L 75.00 -200.00 nmol/L

This is good, he Vit D Council recommends a level of 125nmol/L and the Vit D Society recommends a level between 100-150nmol/L.

Plasma vit B12 543 ng/L 200.00 - 900.00ng/L

According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml (same as ng/L) to at least 450 pg/ml (ng/L) because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml (ng/L)."

So you're above their suggested lower level, not quite at the level where they say deficiencies begin to appear in cerebrospinal fluid, but not a dire result.

TSH 0.22 mu/L 0.35 - 5.00 mu/L

Free T4 22.2 pmoI/L 9.00 - 24.00 pmoI/L

Free T3 4.2 pmoI/L 3,50 - 6.50 pmoI/L

Thyroxine dose changed from 100 / 75 alt days

To 75 mg a day as Dr said TSH was to low and to retest in 3 Months

Your doctor is wrong to dose by TSH, as most of them do. Your thyroid hormone levels - FT4 and FT3 tell you what you need to know. TSH is not a thyroid hormone, it just tells the pituitary to send a message to the thyroid to make thyroxine if it detects there is not enough, the TSH would be high in that case.

Yours is low because you're taking replacement hormone. The most important of all these tests is FT3 which is showing the level of the active hormone (T3) that is available to be taken up by the cells. You have plenty of FT4, but that is a storage hormone and the T4 has to be converted to T3. Your conversion is poor to have such a high FT4 (88% through range) and such a low FT3 (23% through range).

By reducing your dose of Levo your TSH might rise slightly, your FT4 will lower, but your FT3 will also lower and it's low T3 that causes symptoms so you will probably feel more unwell that you do now. Your results show that you would benefit from a slight reduction in Levo and the addition of T3.

Haemoglobin A1c level 43 mmoI/moI 20.00 - 41.00mmoI/moL

This is probably classed as pre-diabetic. I would look into that and see what changes you can make to help yourself.

When you get your Medichecks results back, I would post them, link back to this post so we can compare them, and see if anything is different.

[Breena in reply to SeasideSusie]

Thanks! it would be difficult to feel much worse than I do now .

[Angel_of_the_North]

I think your GP was wrong to reduce dose as those were decent results, although free T3 was still a bit too low. How were you feeling? If your very healthy diet contains a lot of starchy carbs (eg whole grain bread and cereal) that can contribute to pre-diabetes or Type 2 diabetes. So a diet with fewer carbs and more fat (not polyunsaturated fats, which increase inflammation) would probably be more helpful.

[Dadondadda]

I posted more thoroughly on your most recent post, but the A1C may be the smoking gun. Blood sugar issues have a profound impact on your help and the symptoms of impaired glucose tolerance can be extreme.