Ive just received my results from Blue Horizon and wonder if anyone can shed any light on them.
I've been on 125mg Levothyroxine since 2012..originally diagnosed in 2005. Last Sept/Oct i started suffering from complete exhaustion so my gp upped my dose to 150. After a month or so I found I just couldn't sleep. Hot sweats etc..so I reduced back to 125 and soon started to feel tired again. In January Iwent back up to 150. In march i decided to get more tests done with blue horizon.
My results are as follows.
Total T4. 93. (59-154)
Tsh 0.47. (0.27-4.2)
Free thyroxine 19.3 (12-22)
Free T3 4.7 (3.1-6.8)
Reverse T3 18 (10-24)
Vit D 78 (50-200)
Ferritin 45 (30-400)
Folate 4.9 (>2.9)
B12 320. (197-771)
Thyroglubin antibody 10.6 (0-115)
Thyroid peroxidase antibody 200 (0-34)
C reactive protein 0.6 (<5.0)
I've also looked back through my medical history since 2012 and notice my Tsh sits at an average of 2.5.
Any feedback would be appreciated
Thanks
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Hotcurry300
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Your vitamins are too low. I shall let SeasideSusie deal with that
Your TPO antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).
About 90% of all primary hypothyroidism in Uk is due to Hashimoto's
Hashimoto's affects the gut and very often leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can then lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
I also suffer from ulcerative colitis which has been in remission for 3 years and has now returned...I'm trying to see if its this affecting my thyroid or the other way round or is it low vitamins? I've started last weekend on a gluten free diet as I have never tried this before...anything that may help is defo worth a go..thanks
My late husband had ulcerative colitis, and I wish I had known then how important vitamins and minerals are. I would suggest you do some research into vitamins and UC, here's one article to get you started everydayhealth.com/ulcerati...
Be careful about calcium, you need to know that you are deficient before supplementing. And Vit D will increase calcium anyway.
As Magnesium is a cofactor of D3, I would stay away from Magnesium Citrate as you have UC, it can have a laxative effect.
As steroids used in treatment for UC can cause malabsorption, it might be best to find as many sublingual/liquid vitamins and minerals as possible to bypass the stomach.
SlowDragon has mentioned Hashi's and gut problems which are probably the reason for your low nutrient levels. I will answer assuming that you're not taking any supplements.
Vit D 78 (50-200)
This isn't too bad really but not optimal. The Vit D Council recommends a level of 100-150nmol/L so I would supplement with an oral spray (best for absorption when you have Hashi's). BetterYou do a 3000iu spray and I would take 3000iu daily for 3 months then retest. When you've reached the recommended level then you'll need a maintenance dose which may be 2000iu daily, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with City Assays vitamindtest.org.uk/
There are important cofactors needed when taking D3
D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds.
Magnesium helps D3 to work and comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds
BetterYou do a combined D3/K2 spray which might be best for you rather than having a separate K2 supplement.
**
Ferritin 45 (30-400)
For thyroid hormone to work (that's our own as well as replacement hormone) ferritin needs to be at least 70, preferably half way through range. You can help raise your level by eating liver regularly, maximum 200g per week due to it's high Vit A content, and including lots of iron rich foods in your diet apjcn.nhri.org.tw/server/in...
**
B12 320. (197-771)
First of all, check for signs of B12 deficiency here b12deficiency.info/signs-an... If you do have any then pop over to the Pernicious Anaemia Society forum for further advice healthunlocked.com/pasoc as you will need further testing which needs to be carried out before supplementing with B12 or folate/B Complex.
**
Folate 4.9 (>2.9)
This is acceptable because it's over the limit but it's not particularly good. Unfortunately they no longer give ranges but as it's only just over the limit I would assume that it could be much better than this. I would take a B Complex which will raise your folate level, and is a good supplement for us Hypos anyway. My choice would be Thorne Basic B as it contains 400mcg methylfolate which is a better form than folic acid. Stay away from B100s and B50s, they are not balanced, and don't go for one with high dose B6, 10mg is a nice safe dose.
**
Don't start all supplements together. Start with one, give it a week or two and if no reaction then add in the second one, give it another week or two and if no reaction add in the next one, etc. By doing it this way, if you do have any reaction you will know what caused it.
**
Reverse T3 18 (10-24)
C reactive protein 0.6 (<5.0)
Absolutely fine, no problems with either of those.
**
SlowDragon has given you lots of information about Hashi's so there's nothing to add there other than as well as adopting a gluten free diet, supplementing with selenium l-selenomethionine 200mcg daily can also help reduce the antibodies, as can keeping TSH suppressed.
**
Last Sept/Oct i started suffering from complete exhaustion so my gp upped my dose to 150. After a month or so I found I just couldn't sleep. Hot sweats etc..so I reduced back to 125 and soon started to feel tired again. In January Iwent back up to 150.
This will be due to the antibody activity. The antibody attacks cause fluctuations in symptoms and test results.
Adjusting dose when a Hashi's "swing" happens can help, and readjusting when things get back to normal.
I have noticed an annual pattern. I go on holiday for around 3/4weeks every august and spend everyday in the hot sun. After a few days I seem a to spring to life with lots of energy but then struggle to sleep. My apertite increases ten fold and over the next 3 or 4 weeks i struggle to eat enough calories and lose weight. After returning and head towards winter I slow down and start to get exhausted..dry skin..feel low etc. Once the cold weather arrives I really struggle to warm up and even though I work everyday I start to gain weight.
For the,last 5 months I have taken 5000iu vitamin d however it still shows very low.
I am now on a mission to try and improve my overall health so will look at the supplements you recommend many thanks chris
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