NDT dose query.

[arpan13]

Hi everyone,

After two years of trying, following a hystero laproscopy, my wife is pregnant

Pregnancy test kit gave a positive result yesterday.

So we had recently switched to NDT from Levo.

This is my previous post:

healthunlocked.com/thyroidu...

We are currently on 1 + 1/4 grain [ Thyroid -S ]

First day of last period : 18 th September. 6 weeks pregnant.

Need help in deciding the NDT dosage. How much has to be increased ? Please advise.

Current tests results :

***Thyroid tests:

Free T3 : 2.86 pg/ml

Ref Range: 2.04 - 4.40

Free T4 : 0.99 ng/dl

Ref Range: 0.99 - 1.62

TSH : 0.37 uIU/ml

Ref Range :

Non Pregnant: 0.27 - 4.20

1st Trimester:- 0.33 - 4.59

2nd Trimester:- 0.35 - 4.10

3rd Trimester:- 0.21 - 3.15

***HCG:

HCG : 7603 mIU/ml

WEEKS OF PREGNANCY REFERENCE RANGE mIU/ml -------------------- -------------------- BY GESTATION

3 : 5.8 - 71.2

4 : 9.5 - 750

5 : 217 - 7138

6 : 158 - 31795

7 : 3697 - 163563

8 32065 - 149571

9 63803 - 151410

10 46509 - 186977

12 27832 - 210612

14 13950 - 62530

15 12039 - 70971

16 9040 - 56541

17 8175 - 55868

18 8099 - 58176

NON PREGNANT : Not Detectable to 5.3 mIU/ml

***Ferritin : 25.3 ng/ml

Ref Range: 13 - 150

***Total Iron 52.2 ugm/dl

Ref Range: 28 - 170

***T.I.B.C. 317.4 ugm/dl

Ref Range: 255 - 450

***Transferrin Saturation 16.4 %

Ref Range: 20 - 50

***Progesterone : Result awaiting.

[Clutter]

Congratulations, Arpan13

In the UK it is desirable to have TSH of pregnant women in the low-normal range 0.4 - 2.5 so your wife's TSH is fine. It is customary to increase Levothyroxine dose by 25-50mcg when pregnancy is confirmed to ensure good foetal development. An equivalent dose is 1/2 to 3/4 of a grain NDT.

Ferritin and iron are low in range so I would suggest your wife supplement's iron with 1,000mg vitamin C which will aid absorption and minimise constipation. Iron should be taken 4 hours away from NDT.

[arpan13 in reply to Clutter]

Thank you Clutter

So, as per the lab reports should i increase by 1/2 or 3/4 ?

We tried Solgar gentle 25 mg iron caps with 500 mg Vit C , but she was having severe headaches everytime she took them. So, we stopped it.

Shall I try a different brand? and is it safe to take vitamin supplements during pregnancy?

[Clutter in reply to arpan13]

Arpan13,

Yes, I would increase by 1/2 grain and retest in 6-8 weeks aiming to keep TSH <2.5.

Try the Solgar iron again. Iron is more likely to cause upset stomach than headache.

[arpan13 in reply to Clutter]

Ok, will increase the dosage by 1/2 grain.

Will give Solgar one more try.

Apart from solgar, we have Vit D3 2000 iu capsules, Vit K2MK7 200 mcg capsules, Vit C 500 mg chewable tablets.

Are these supplements safe during pregnancy ?

[Clutter in reply to arpan13]

Arpan13,

Unless supplements have been tested on pregnant women it isn't possible to say they are safe. What is not good during pregnancy is having low iron, low B12, low folate and low vitD. I would prefer to have blood tests to check whether levels are low and that supplementation is necessary before supplementing with the exception of folic acid which taken pre and during pregnancy may help prevent neural tube defects in the foetus (spina bifida).

[arpan13 in reply to Clutter]

Will get vit d, b12 and folate tests done soon. We have started Folinext D one capsule every night.

[Camdentown]

Congratulations to you both! I wish your wife a healthy and happy pregnancy. 😀

[arpan13 in reply to Camdentown]

Thank you for your kind wishes