I have recently come off HRT (having tried several over the last 5 years), can this affect the thyroid? I have heard that progesterone and estrogen can cause an imbalance of the thyroid. I am on T4 and T3 still trial and error. Still have weight gain and numerous other symptoms. Taking Vit D, Selenium, Vit C, Iron, Folic Acid. I have noticed that my stress incontinence has come back, urination frequency. Never had the flushes etc. I am 57. It is just that I have been diagnosed with cervical spondylosis, and yesterday found out that I have degenerative osteoarthritis in my left foot. Will be having another root nerve canal (18weeks waiting list) had one already but did not help for long. Also another injection in my foot soot or cortisone. It's just the bone side had scans done twice over the years and told they are ok due another next year. The Endo told me that I could have a yearly injection to protect my bones, so not necessary to take HRT. Would be grateful for any advise please.