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Vitamin B12 deficiency
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Vital Role of B12 and Folate
https://www.sciencedirect.com/science/article/abs/pii/S0193953X12001001?via%3Dihub This article focuses on the role of b12 and folate in the synthesis of methionine and one of the side effects of improper synthesis is depression and cognitive impairment. However, I want to emphasise that poor synthesis
https://www.sciencedirect.com/science/article/abs/pii/S0193953X12001001?via%3Dihub This article focuses on the role of b12 and folate in the synthesis of methionine and one of the side effects of improper synthesis is depression and cognitive impairment. However, I want to emphasise that poor synthesis
B12life
in
Pernicious Anaemia Society
4 months ago
Folate when SI?
Hi everyone, How much folate is recommended when injecting B12? The folate tablets I have are 400µg. Also, can anyone kindly comment on my sudden lip problems? I awoke 4 mornings ago to blistered lips, they were slightly worse the next morning. The blistering seems to have stopped but my lips are
Hi everyone, How much folate is recommended when injecting B12? The folate tablets I have are 400µg. Also, can anyone kindly comment on my sudden lip problems? I awoke 4 mornings ago to blistered lips, they were slightly worse the next morning. The blistering seems to have stopped but my lips are
J972
in
Pernicious Anaemia Society
4 months ago
Update and latest results
Hello again lovely people. I thought I’d come back and update having been on Levo 50mcg since diagnosis 3 months ago. In early January the GP asked me to retest and only TSH was done (big let down but not unexpected)! I was amazed that after only 2 months on Levo 50mcg that my TSH had dropped to 0.44
Hello again lovely people. I thought I’d come back and update having been on Levo 50mcg since diagnosis 3 months ago. In early January the GP asked me to retest and only TSH was done (big let down but not unexpected)! I was amazed that after only 2 months on Levo 50mcg that my TSH had dropped to 0.44
Gardeningaddict
in
Thyroid UK
4 months ago
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Help with latest bloods please!
hi everyone I’m on 50mcg of Levothyroxine for Hashimotos and my original test results are in my profile. I’ve just had some bloods done with the GP and they’ve said no further action is required. I’m conscious that there is a difference between being within range and optimal, so I thought I’d come on
hi everyone I’m on 50mcg of Levothyroxine for Hashimotos and my original test results are in my profile. I’ve just had some bloods done with the GP and they’ve said no further action is required. I’m conscious that there is a difference between being within range and optimal, so I thought I’d come on
Smartypants1
in
Thyroid UK
4 months ago
Updated results
Morning all, I posted some results a while ago and followed the very wise advice I was given but as I still felt rubbish I got into my GP who was very helpful and ordered lots of tests for me. When I posted towards the end of last year I was struggling and my B12 was low, ferritin dire at 16 and some
Morning all, I posted some results a while ago and followed the very wise advice I was given but as I still felt rubbish I got into my GP who was very helpful and ordered lots of tests for me. When I posted towards the end of last year I was struggling and my B12 was low, ferritin dire at 16 and some
Peril1504
in
Thyroid UK
4 months ago
Advice on new bloods please
Hi, Can anyone give me their insight to my new bloods, correctly taken. I have an endo appointment tomorrow and have been on levothyroxine first 3 months Teva and now a month of Accord all at 50 micrograms. Vitamin D 49 (50-200) insufficient Magnesium 1.07 (0.66-0.99) high CRP 1.71 (<5.0)
Hi, Can anyone give me their insight to my new bloods, correctly taken. I have an endo appointment tomorrow and have been on levothyroxine first 3 months Teva and now a month of Accord all at 50 micrograms. Vitamin D 49 (50-200) insufficient Magnesium 1.07 (0.66-0.99) high CRP 1.71 (<5.0)
Purple450
in
Thyroid UK
4 months ago
Gypsy pains.
Hi again everyone. I was just wondering if anyone has experienced what we call "traveling" pains. For ex; I may have throbbing pain in my wrist and then 10 minutes later my wrist does not hurt at all, but then the back of my thighs ache like crazy and then a few min later my jaw hurts and then after
Hi again everyone. I was just wondering if anyone has experienced what we call "traveling" pains. For ex; I may have throbbing pain in my wrist and then 10 minutes later my wrist does not hurt at all, but then the back of my thighs ache like crazy and then a few min later my jaw hurts and then after
MrJustatip
in
Pernicious Anaemia Society
9 months ago
4 week trial results.
I reviewed in depth the rationale for the amount of B12 that is effective and found it to not be based on credible science, specifically retention times based on the general population and no knowledge base on how the injection is used by the body at the cellular level with regards to frequency. The
I reviewed in depth the rationale for the amount of B12 that is effective and found it to not be based on credible science, specifically retention times based on the general population and no knowledge base on how the injection is used by the body at the cellular level with regards to frequency. The
WIZARD6787
in
Pernicious Anaemia Society
4 months ago
Fatigue, anaemia and chest pain
Hi everyone ☺️ I got diagnosed with stage 2 endo after a lap last November. We're trying to conceive so haven't been prescribed any meds to manage the endo. Just waiting for an IVF appointment. I've stopped eating gluten, not having caffeine or alcohol. Taking supplements. Eating well, sleeping well,
Hi everyone ☺️ I got diagnosed with stage 2 endo after a lap last November. We're trying to conceive so haven't been prescribed any meds to manage the endo. Just waiting for an IVF appointment. I've stopped eating gluten, not having caffeine or alcohol. Taking supplements. Eating well, sleeping well,
Bluebells86
in
Endometriosis UK
4 months ago
SI vs Self-treating
I started using the term self-treating as soon as I started to inject. In the USA I was prescribed 8 weekly cyno 1mg IM then 1mg cyno and 1 mg folic oral daily for life. No further treatment necessary. I did improve but not much. My impetus to self-treat was at first driven to prevent permanent damage
I started using the term self-treating as soon as I started to inject. In the USA I was prescribed 8 weekly cyno 1mg IM then 1mg cyno and 1 mg folic oral daily for life. No further treatment necessary. I did improve but not much. My impetus to self-treat was at first driven to prevent permanent damage
WIZARD6787
in
Pernicious Anaemia Society
9 months ago
B12 ampoules
Can't find post but wondered if there was an outcome to only half the amount in .0.5ml rather than 1mg/1ml Was it an error of user? Or syringe Or was it a batch of b12 faulty?
Can't find post but wondered if there was an outcome to only half the amount in .0.5ml rather than 1mg/1ml Was it an error of user? Or syringe Or was it a batch of b12 faulty?
Nackapan
in
Pernicious Anaemia Society
9 months ago
Promethazine Hydrochloride
hi I have been desperate for sleep but my RLS has been so bad that I’ve found it impossible I managed to get a GP appointment and told her my story and background and although she was sympathetic said the RLS I’d very difficult to control I told her I had no desire to go back on to a DA and my problems
hi I have been desperate for sleep but my RLS has been so bad that I’ve found it impossible I managed to get a GP appointment and told her my story and background and although she was sympathetic said the RLS I’d very difficult to control I told her I had no desire to go back on to a DA and my problems
Hoochybaby
in
Restless Legs Syndrome
7 months ago
Help with Thyroid results please.
hi everyone, I would be grateful for some advice on thyroid results for my younger brother please. I have Auto immune Hypo since 2004 and so does one of my brothers and my mum. My other brother has had lots of symptoms of depression and has deteriorated recently. He has high anxiety and slightly paranoid
hi everyone, I would be grateful for some advice on thyroid results for my younger brother please. I have Auto immune Hypo since 2004 and so does one of my brothers and my mum. My other brother has had lots of symptoms of depression and has deteriorated recently. He has high anxiety and slightly paranoid
CarolineAnne
in
Thyroid UK
4 months ago
PALVE
I’m about to start b12 injections alternate days for two weeks then every 3 months. I appreciate this isn’t enough for neurological problems which I have. Should I ask for blood tests for folic acid before I start and then take every day .. and for how long? I’m not going down the path of SI for lots
I’m about to start b12 injections alternate days for two weeks then every 3 months. I appreciate this isn’t enough for neurological problems which I have. Should I ask for blood tests for folic acid before I start and then take every day .. and for how long? I’m not going down the path of SI for lots
Palum
in
Pernicious Anaemia Society
4 months ago
How many times should we wait for new B12 level testing after loading doses?
Hello dear friends. I wondered if how many times should we wait for a new B12 serum level test. I did my loading doses that can be reliableAppreciate any assistance
Hello dear friends. I wondered if how many times should we wait for a new B12 serum level test. I did my loading doses that can be reliableAppreciate any assistance
Emiroskui
in
Pernicious Anaemia Society
9 months ago
Help with results
Auto immune hypothyroid taking 100mcg Levo. Take iron tablets as ferritin usually 50-60 without. Suspected IBS and lots of gut issues. Feeling tired, aching weak feeling and some symptoms of low B12/folate but all results are in range and considered normal. Serum TSH level: 0.7 mIU/L (range 0.4
Auto immune hypothyroid taking 100mcg Levo. Take iron tablets as ferritin usually 50-60 without. Suspected IBS and lots of gut issues. Feeling tired, aching weak feeling and some symptoms of low B12/folate but all results are in range and considered normal. Serum TSH level: 0.7 mIU/L (range 0.4
pinklady756
in
Thyroid UK
4 months ago
Update
I had a call from surgery re blood test to say I should pick up a script for 50mcg Levothyroxine which is double the daily dose I have been on. Another blood test in 6 weeks. My problem is I have been fine on 25mcg lots of energy as long as I get my B12 I wonder at GP changing meds without any consultation
I had a call from surgery re blood test to say I should pick up a script for 50mcg Levothyroxine which is double the daily dose I have been on. Another blood test in 6 weeks. My problem is I have been fine on 25mcg lots of energy as long as I get my B12 I wonder at GP changing meds without any consultation
Monbretia
in
Thyroid UK
9 months ago
Desperate for direction
I am diagnosed hypothyroid. I take 75mg levothyroxine a day. i have had my latest thyroid results from Monitor My Health. I think they use NHS ranges. 15/01/2024 3.7 pmol/L FT3 levels normal (normal range 3.1 - 6.8 pmol/L) thyroxine 15/01/2024 16.4 pmol/L FT4 levels normal (normal range 12 -
I am diagnosed hypothyroid. I take 75mg levothyroxine a day. i have had my latest thyroid results from Monitor My Health. I think they use NHS ranges. 15/01/2024 3.7 pmol/L FT3 levels normal (normal range 3.1 - 6.8 pmol/L) thyroxine 15/01/2024 16.4 pmol/L FT4 levels normal (normal range 12 -
Bluekipper
in
Thyroid UK
4 months ago
Folate Levels ?
I am still trying to feel well ? With symptoms including severe fatigue and weakness, disorientation, and joint and body pains. Can you please let meknow if I might need to increase my Folate level - as although within range - at 13 - I think I had read here that it is best if it is at least 50% through
I am still trying to feel well ? With symptoms including severe fatigue and weakness, disorientation, and joint and body pains. Can you please let meknow if I might need to increase my Folate level - as although within range - at 13 - I think I had read here that it is best if it is at least 50% through
Lemondrizz
in
Thyroid UK
4 months ago
Update
I am still working out my next trial. I am having issues with procurement which is no fun. I now can reduce or eliminate a supplement and in a few days tell what the effect is, to my satisfaction. I call it incipit symptoms. I can tell they are going to return with a vengeance due to prior trials.
I am still working out my next trial. I am having issues with procurement which is no fun. I now can reduce or eliminate a supplement and in a few days tell what the effect is, to my satisfaction. I call it incipit symptoms. I can tell they are going to return with a vengeance due to prior trials.
WIZARD6787
in
Pernicious Anaemia Society
9 months ago
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