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1Trial of Bradykinesia Stem Cell Therapy Now Dosing Last Group
IMAC Holdings has started dosing the third and final group of participants in a Phase 1 clinical trial assessing the potential of its umbilical cord-derived stem cell therapy for treating bradykinesia, an early motor symptom of Parkinson’s disease characterized by slowness or difficulty in movement.
IMAC Holdings has started dosing the third and final group of participants in a Phase 1 clinical trial assessing the potential of its umbilical cord-derived stem cell therapy for treating bradykinesia, an early motor symptom of Parkinson’s disease characterized by slowness or difficulty in movement.
Farooqji
in
Cure Parkinson's
2 years ago
The coming rejuvenation biotechnology revolution for Parkinson's disease - Michael Rae and Dr. Robert Rodgers discuss Parkinson’s and aging
Hey Turnipbarrow , it is your fault I found this. Touches on Zombie neurons! The coming rejuvenation biotechnology revolution for Parkinson's disease - Michael Rae and Dr. Robert Rodgers discuss Parkinson’s and aging https://www.blogtalkradio.com/parkinsons-recovery/2022/01/09/the-coming-rejuvenation-biotechnology-revolution-for-parkinsons-disease
Hey Turnipbarrow , it is your fault I found this. Touches on Zombie neurons! The coming rejuvenation biotechnology revolution for Parkinson's disease - Michael Rae and Dr. Robert Rodgers discuss Parkinson’s and aging https://www.blogtalkradio.com/parkinsons-recovery/2022/01/09/the-coming-rejuvenation-biotechnology-revolution-for-parkinsons-disease
Bolt_Upright
in
Cure Parkinson's
2 years ago
Encouraging Stem Cell Trial Results
Top-line Parkinson's Disease Clinical Trial Results ISCO successfully completed the treatment phase of its dose escalating phase 1 clinical trial (ClinicalTrials.gov Identifier: NCT02452723) evaluating the safety, tolerability, and preliminary efficacy of its lead candidate, ISC-hpNSC® for the treatment
Top-line Parkinson's Disease Clinical Trial Results ISCO successfully completed the treatment phase of its dose escalating phase 1 clinical trial (ClinicalTrials.gov Identifier: NCT02452723) evaluating the safety, tolerability, and preliminary efficacy of its lead candidate, ISC-hpNSC® for the treatment
jimcaster
in
Cure Parkinson's
2 years ago
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A randomized clinical trial of burst vs. spaced physical therapy for Parkinsons disease
https://www.prd-journal.com/article/S1353-8020(22)00054-2/fulltext
https://www.prd-journal.com/article/S1353-8020(22)00054-2/fulltext
Farooqji
in
Cure Parkinson's
2 years ago
Recording available - Dr. Jonathan Sackner-Bernstein: "What If I Discovered the Silver Bullet?"
Thank you to Dr. Jonathan Sackner-Bernstein for his excellent, thought-provoking presentation yesterday titled "What if I discovered the Silver Bullet?" Motivated by a friend’s suffering from Parkinson’s, Dr. Sackner-Bernstein focused on a gap in our understanding of the disease: no one had so far measured
Thank you to Dr. Jonathan Sackner-Bernstein for his excellent, thought-provoking presentation yesterday titled "What if I discovered the Silver Bullet?" Motivated by a friend’s suffering from Parkinson’s, Dr. Sackner-Bernstein focused on a gap in our understanding of the disease: no one had so far measured
Michel0220
in
Cure Parkinson's
2 years ago
Focus on thalassemia and polycythemia vera.
« Silence Therapeutics’ stuttering effort to generate clinical data on SLN124 in myelodysplastic syndrome (MDS) has conked out. Facing recruitment challenges, the RNAi specialist has decided to stop enrollment in the MDS arm of an early-phase clinical trial to focus on thalassemia and polycythemia vera
« Silence Therapeutics’ stuttering effort to generate clinical data on SLN124 in myelodysplastic syndrome (MDS) has conked out. Facing recruitment challenges, the RNAi specialist has decided to stop enrollment in the MDS arm of an early-phase clinical trial to focus on thalassemia and polycythemia vera
Manouche
in
MPN Voice
2 years ago
People of HU: Meet Hazel - Overcoming My Fear to Survive Kidney Cancer
March is kidney cancer awareness month. According to Cancer Research UK, Kidney cancer is the seventh most common cancer in the UK with 36 new cases being diagnosed every day. In this blog post, Hazel shares her story of being diagnosed with kidney cancer and overcoming her fear to proceed with the
March is kidney cancer awareness month. According to Cancer Research UK, Kidney cancer is the seventh most common cancer in the UK with 36 new cases being diagnosed every day. In this blog post, Hazel shares her story of being diagnosed with kidney cancer and overcoming her fear to proceed with the
SaskiaHU
HealthUnlocked
in
HealthUnlocked Blog
2 years ago
Decision time Lutetium or AM509
M1, five bone lesions, mCRPC with PSA now doubling each month (currently at 1.7), after failure of abiraterone. I've been offered a "slot" for two clinical trials: AMG509, a bi-specific T-cell engager, and a new version of Lutetium therapy, called Lu-DOTA-TLX590-CHO (which they say is novel, and seems
M1, five bone lesions, mCRPC with PSA now doubling each month (currently at 1.7), after failure of abiraterone. I've been offered a "slot" for two clinical trials: AMG509, a bi-specific T-cell engager, and a new version of Lutetium therapy, called Lu-DOTA-TLX590-CHO (which they say is novel, and seems
MarkEmrys
in
Advanced Prostate Cancer
2 years ago
Abiraterone and fatigue in 78 year old dad
Abiraterone and fatigue Hi my dad is 78 in April and lives in England. He had prostate surgery in 2019 but cancer had already spread. He's had chemo and ADT. His PSA went from 3.3 last Sept to 7.9 in November. A PSMA scan revealed he had Mets to Lymph nodes and some low-volume skeletal lesions in right
Abiraterone and fatigue Hi my dad is 78 in April and lives in England. He had prostate surgery in 2019 but cancer had already spread. He's had chemo and ADT. His PSA went from 3.3 last Sept to 7.9 in November. A PSMA scan revealed he had Mets to Lymph nodes and some low-volume skeletal lesions in right
Lemonpower
in
Advanced Prostate Cancer
2 years ago
Third Jevtana/Carboplatin treatment completed. Total of 10 chemo treatments are now completed overall. Hoping for better results.
PSA increase as seen above. My oncologist's response was "This may be the roller coaster that your PSA is following We will continue to monitor the levels and symptoms" Seems to me the best part of the old wooden coaster was cresting the top of the climb and plunging to the bottom. Hopefully, my next
PSA increase as seen above. My oncologist's response was "This may be the roller coaster that your PSA is following We will continue to monitor the levels and symptoms" Seems to me the best part of the old wooden coaster was cresting the top of the climb and plunging to the bottom. Hopefully, my next
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
Parkinson’s Disease: Can Targeting Inflammation Be an Effective Neuroprotective Strategy? 2021
There is a LOT to read in this article. And it is very detailed and I did not understand most of it. But if you browse through it, things will pop out. Tidbits. Clues. Parkinson’s Disease: Can Targeting Inflammation Be an Effective Neuroprotective Strategy? https://www.frontiersin.org/articles/10.3389
There is a LOT to read in this article. And it is very detailed and I did not understand most of it. But if you browse through it, things will pop out. Tidbits. Clues. Parkinson’s Disease: Can Targeting Inflammation Be an Effective Neuroprotective Strategy? https://www.frontiersin.org/articles/10.3389
Bolt_Upright
in
Cure Parkinson's
2 years ago
COVID and stage 4 HRPC warning!!
While waiting to join a clinical trial my bf got I'll. He stopped eating, had nausea and vomiting , chills , cough and weakness. Concerned about possible pneumonia , I took him to the ER. I explained all the symptoms and informed them about his vaccines. As soon as a hospitalist saw him and diagnosed
While waiting to join a clinical trial my bf got I'll. He stopped eating, had nausea and vomiting , chills , cough and weakness. Concerned about possible pneumonia , I took him to the ER. I explained all the symptoms and informed them about his vaccines. As soon as a hospitalist saw him and diagnosed
Michelle56pr
in
Prostate Cancer Network
2 years ago
Lutetium-617 vs Lutetium-TLX591 plus Xyandi after Zytiga failure. Question from Australia.
Hi from Australia Congrats on FDA approval for Lutetium! I’m looking for any information about lutetium TLX591 which is being used in prostACT clinical trial here. Considering joining this trial vs lutetium 617 (used in VISION trial and the mainstay of lutetium therapy for quite some time here, Germany
Hi from Australia Congrats on FDA approval for Lutetium! I’m looking for any information about lutetium TLX591 which is being used in prostACT clinical trial here. Considering joining this trial vs lutetium 617 (used in VISION trial and the mainstay of lutetium therapy for quite some time here, Germany
MarkEmrys
in
Advanced Prostate Cancer
2 years ago
Low-carb diet - ketogenesis - PSADT
New study from Steve Freedland et al. "
Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial
" [1] Bottom line: Low-carb diet may lenghthen
New study from Steve Freedland et al. "
Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial
" [1] Bottom line: Low-carb diet may lenghthen
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Another study on T3 given to women with ongoing symptoms
This downloadable paper (I don't think I've posted this before, so apologies if I have) describes a trial of giving T3 to women patients with residual symptoms on T4 only.
Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual Symptoms on Levothyroxine Therapy
This downloadable paper (I don't think I've posted this before, so apologies if I have) describes a trial of giving T3 to women patients with residual symptoms on T4 only.
Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual Symptoms on Levothyroxine Therapy
diogenes
in
Thyroid UK
2 years ago
Shining a light on Protein Aggregation in Parkinson's Disease
Niacin, who knew?! Research shows that in the brain, niacin interacts with a highly-selective receptor, HCAR2, present in immune cells physically associated with amyloid plaques. When niacin activates the receptor, it stimulates beneficial actions from these immune cells. After the Alzheimer's disease
Niacin, who knew?! Research shows that in the brain, niacin interacts with a highly-selective receptor, HCAR2, present in immune cells physically associated with amyloid plaques. When niacin activates the receptor, it stimulates beneficial actions from these immune cells. After the Alzheimer's disease
SilentEchoes
in
Cure Parkinson's
2 years ago
To qualify for Pluvicto, one needs a positive PSMA PET scan, but...
The FDA has only approved one kind of PSMA PET indicator (Ga68PSMA11) to qualify for Pluvicto. Two kinds of PSMA PET indicators are FDA-approved for recurrent patients and high-risk patients: Pylarify and Ga68PSMA11.
Pylarify
, made by Progenics pharmaceuticals, is widely available: https://www.pylarify.com
The FDA has only approved one kind of PSMA PET indicator (Ga68PSMA11) to qualify for Pluvicto. Two kinds of PSMA PET indicators are FDA-approved for recurrent patients and high-risk patients: Pylarify and Ga68PSMA11.
Pylarify
, made by Progenics pharmaceuticals, is widely available: https://www.pylarify.com
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Clinical trial!!!
Have any of you heard of this phase one trial? The drug is Inobrodib! I believe the case number is CSS1477. If any of you could help me in regards to this I would so appreciate it. It was offered to my husband. Hopefully we can get to Boston as often as they would like. It’s three times a week for a
Have any of you heard of this phase one trial? The drug is Inobrodib! I believe the case number is CSS1477. If any of you could help me in regards to this I would so appreciate it. It was offered to my husband. Hopefully we can get to Boston as often as they would like. It’s three times a week for a
Fight11
in
Advanced Prostate Cancer
2 years ago
Lu-177 clinical trial university of Chicago
Husband is on the 5th of 6th isotopes in study. He has had very little side effects(if any). We are hearing that it is close to having FDA approval. PSA has dropped to 0.32. We are hoping to get many months without any treatment other than lupron.
Husband is on the 5th of 6th isotopes in study. He has had very little side effects(if any). We are hearing that it is close to having FDA approval. PSA has dropped to 0.32. We are hoping to get many months without any treatment other than lupron.
Cynthgob
in
Advanced Prostate Cancer
2 years ago
Overcoming Drug Resistance in Advanced Prostate Cancer by Drug Repurposing
https://pubmed.ncbi.nlm.nih.gov/35225948/ There must be more to this but can't figure out how to expand it. Hisham F Bahmad 1, Timothy Demus 2, Maya M Moubarak 3 4, Darine Daher 5, Juan Carlos Alvarez Moreno 1, Francesca Polit 1, Olga Lopez 6, Ali Merhe 7, Wassim Abou-Kheir 3, Alan M Nieder 2 6, Robert
https://pubmed.ncbi.nlm.nih.gov/35225948/ There must be more to this but can't figure out how to expand it. Hisham F Bahmad 1, Timothy Demus 2, Maya M Moubarak 3 4, Darine Daher 5, Juan Carlos Alvarez Moreno 1, Francesca Polit 1, Olga Lopez 6, Ali Merhe 7, Wassim Abou-Kheir 3, Alan M Nieder 2 6, Robert
Scout4answers
in
Advanced Prostate Cancer
2 years ago
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