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phase 1 clinical trials at Royal Marsden — anyone has experience?
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
Lookingahead
in
My Ovacome
2 years ago
After 11 years, dad has started chemo for the first time
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
PHnerd
in
Advanced Prostate Cancer
2 years ago
This helps you and us
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Darryl
Partner
in
Prostate Cancer Caregivers
2 years ago
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This helps you and us
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Darryl
Partner
in
Prostate Cancer And Gay Men
2 years ago
This is how to help you and us
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Darryl
Partner
in
Prostate Cancer Network
2 years ago
This is how to help you and us
Dear Particpants of Malecare's Advanced Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Advanced Prostate Cancer community
Dear Particpants of Malecare's Advanced Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Advanced Prostate Cancer community
Darryl
Partner
in
Advanced Prostate Cancer
2 years ago
M1774 plus Niraparib clinical trial
hi , has anyone been in the trial of M1774 either in its own or with Niraparib ? I have just been offered this at the Royal Marsden . Any feedback would be greatly appreciated!! Enjoy your Christmas all . Hopefully we can all forget about the big C for one day !!! x x
hi , has anyone been in the trial of M1774 either in its own or with Niraparib ? I have just been offered this at the Royal Marsden . Any feedback would be greatly appreciated!! Enjoy your Christmas all . Hopefully we can all forget about the big C for one day !!! x x
Lookingahead
in
My Ovacome
2 years ago
Any ideas on blood labs to monitor for earlier detection than PSA for becoming Castrate Resistant?
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and Nubeqa) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH. Conclusion: Our analysis suggested the association
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and Nubeqa) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH. Conclusion: Our analysis suggested the association
KocoPr
in
Advanced Prostate Cancer
2 years ago
Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson’s Disease: A Review
Abstract Neurodegenerative disease is a collective term given for the clinical condition, which results in progressive degeneration of neurons and the loss of functions associated with the affected brain region. Apart from the increase in age, neurodegenerative diseases are also partly affected by diet
Abstract Neurodegenerative disease is a collective term given for the clinical condition, which results in progressive degeneration of neurons and the loss of functions associated with the affected brain region. Apart from the increase in age, neurodegenerative diseases are also partly affected by diet
Thal
in
Cure Parkinson's
2 years ago
BITE Clinical Study
My husband was told he only has two treatment options at this point. One is starting Jevtana, but at a lower than normal dose due to his neutrophils being only 1150. The other would be to participate in a clinical trial called BITE in Louisville. I am afraid I don’t recall what BITE is an acronym for
My husband was told he only has two treatment options at this point. One is starting Jevtana, but at a lower than normal dose due to his neutrophils being only 1150. The other would be to participate in a clinical trial called BITE in Louisville. I am afraid I don’t recall what BITE is an acronym for
Wyldhare22
in
Advanced Prostate Cancer
2 years ago
New drug approved for those with KRAS G-12C
On December 12th, 2022, the Food and Drug Administration (FDA) approved Krazati (adagrasib) for treatment of non-small cell lung cancer (nsclc) where there is a KRAS G12C mutation. This approval is for patients who have received at least one line of prior treatment such as chemotherapy. The FDA based
On December 12th, 2022, the Food and Drug Administration (FDA) approved Krazati (adagrasib) for treatment of non-small cell lung cancer (nsclc) where there is a KRAS G12C mutation. This approval is for patients who have received at least one line of prior treatment such as chemotherapy. The FDA based
Miranda_GO2
Partner
in
Lung Cancer Support
2 years ago
Urso blocks COVID - research today from Addenbrooke's Hospital, Cambridge
15h Dec 2022 at 14:15 UK time : On the BBC World Service programme Healthcheck, right now. Liver consultant from Addenbrooke's reporting that they have discovered that Urso protects against COVID. Medic says that Urso blocks COVID's ability to enter human cells. 'It shuts the doorway (into the cell
15h Dec 2022 at 14:15 UK time : On the BBC World Service programme Healthcheck, right now. Liver consultant from Addenbrooke's reporting that they have discovered that Urso protects against COVID. Medic says that Urso blocks COVID's ability to enter human cells. 'It shuts the doorway (into the cell
Wilderswimmer
in
PBCers Organization
2 years ago
Delivery of mRNA therapies: Moderna's founder Bob Langer discusses past, present, and future
[i]"mRNA is expected to become one of the major pillars of drug development. With an increasing number of concepts entering clinical trials, the first approval of an mRNA therapeutic against cancer is nearing" [/i]are the concluding lines of a review paper published in April 2021 https://molecular-cancer.biomedcentral.com
[i]"mRNA is expected to become one of the major pillars of drug development. With an increasing number of concepts entering clinical trials, the first approval of an mRNA therapeutic against cancer is nearing" [/i]are the concluding lines of a review paper published in April 2021 https://molecular-cancer.biomedcentral.com
bennevisplace
in
CLL Support
2 years ago
The Vaccines are coming[b] [/b]
https://www.yahoo.com/now/moderna-merck-announce-mrna-4157-120000391.html Moderna and Merck Announce mRNA-4157/V940, an Investigational Personalized mRNA Cancer Vaccine, in Combination with KEYTRUDA(R) (pembrolizumab), Met Primary Efficacy Endpoint in Phase 2b KEYNOTE-942 Trial Moderna, Inc. Tue,
https://www.yahoo.com/now/moderna-merck-announce-mrna-4157-120000391.html Moderna and Merck Announce mRNA-4157/V940, an Investigational Personalized mRNA Cancer Vaccine, in Combination with KEYTRUDA(R) (pembrolizumab), Met Primary Efficacy Endpoint in Phase 2b KEYNOTE-942 Trial Moderna, Inc. Tue,
Scout4answers
in
Advanced Prostate Cancer
2 years ago
18 Month Update
Brief Summary Gleason 4+5 with Intraductal histology T3b n1 Brca2. After 18 months of ADT plus Abiraterone and HDR Brachytherapy and EBRT my WBC is within normal limits for the first time since HDR Brachytherapy. My PSA started at 10.28 and decreased 95% the first month of ADT and slowly after that
Brief Summary Gleason 4+5 with Intraductal histology T3b n1 Brca2. After 18 months of ADT plus Abiraterone and HDR Brachytherapy and EBRT my WBC is within normal limits for the first time since HDR Brachytherapy. My PSA started at 10.28 and decreased 95% the first month of ADT and slowly after that
TylexGP
in
Advanced Prostate Cancer
2 years ago
Starting my prostate cancer journey after radical prostatectomy. Looking for info, suggestions or recommendations on future treatments.
Hello everyone, I am 67 and had a PSA of 8.9 and a grade group 4 Gleason score of 4+4=8. I had radical prostatectomy with lymph node dissection on 12/1/2022. I am on the road to recovery. The pathology report showed 60-70 % of prostate involved by tumor with extraprostatic extension present, non
Hello everyone, I am 67 and had a PSA of 8.9 and a grade group 4 Gleason score of 4+4=8. I had radical prostatectomy with lymph node dissection on 12/1/2022. I am on the road to recovery. The pathology report showed 60-70 % of prostate involved by tumor with extraprostatic extension present, non
MrDexter
in
Advanced Prostate Cancer
2 years ago
Experimental cancer therapy shows success in more than 70% of patients in global clinical trials
Myeloma is only cancer mentioned https://medicalxpress.com/news/2022-12-experimental-cancer-therapy-success-patients.html?utm_source=join1440&utm_medium=email&utm_placement=newsletter
Myeloma is only cancer mentioned https://medicalxpress.com/news/2022-12-experimental-cancer-therapy-success-patients.html?utm_source=join1440&utm_medium=email&utm_placement=newsletter
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Fine-Tuning the Wave of Innovation in CLL
ASH2022 is happening in New Orleans, right now. Yesterday, there was a great webinar hosted on the PeerView platform that covered Personalized Models for Upfront and Sequential Care With Groundbreaking Treatment, which should be of interest to anyone contemplating firstline or relapsed/refractory treatment
ASH2022 is happening in New Orleans, right now. Yesterday, there was a great webinar hosted on the PeerView platform that covered Personalized Models for Upfront and Sequential Care With Groundbreaking Treatment, which should be of interest to anyone contemplating firstline or relapsed/refractory treatment
SeymourB
in
CLL Support
2 years ago
Treatment of Richter's syndrome - ASH 2022 Education Program
This year's American Society of Hematology (ASH) annual conference is now underway and the ASH Education Program, Volume 2022, Issue 1 booklet that was published on 9 December 2022 is now available at: https://ashpublications.org/hematology/issue/2022/1 It contains three review articles from sessions
This year's American Society of Hematology (ASH) annual conference is now underway and the ASH Education Program, Volume 2022, Issue 1 booklet that was published on 9 December 2022 is now available at: https://ashpublications.org/hematology/issue/2022/1 It contains three review articles from sessions
CLLerinOz
Administrator
in
CLL Support
2 years ago
Lu-177 as SOC vs Clinical Trial
Many thanks to all contributors! Since I've now just had my 16th cabazitazel/carboplatin chemo treatment, we're looking at options and working on Lu-177. I'm curious that, since Lu-177 is now FDA approved and is Standard Of Care, is there an advantage to seeking a clinical trial vs receiving it as
Many thanks to all contributors! Since I've now just had my 16th cabazitazel/carboplatin chemo treatment, we're looking at options and working on Lu-177. I'm curious that, since Lu-177 is now FDA approved and is Standard Of Care, is there an advantage to seeking a clinical trial vs receiving it as
MechD
in
Advanced Prostate Cancer
2 years ago
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