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RT with ADT Relogolix (Orgovyx) vs Enzalutamide (Xtandi) Side Effect Differences?
Of note, Enzalutamide has direct radio sensitizing properties where ADT drugs only have an indirect radio sensitizing effect from lowering
Testosterone
.
Of note, Enzalutamide has direct radio sensitizing properties where ADT drugs only have an indirect radio sensitizing effect from lowering
Testosterone
.
jazj
in
Advanced Prostate Cancer
5 months ago
Thyroid results
I'm in surgical menopause and taking
Testosterone
, Oestrogen and Progesterone and all my levels are good for those so I'm wondering if it could be thyroid related? Any advice would be greatly appreciated. TSH - 2.550 FT4 - 14.20 FT3 - 4.06 Anti TPO - 9.95 Anti TG - 14.8 Thank you 😊
I'm in surgical menopause and taking
Testosterone
, Oestrogen and Progesterone and all my levels are good for those so I'm wondering if it could be thyroid related? Any advice would be greatly appreciated. TSH - 2.550 FT4 - 14.20 FT3 - 4.06 Anti TPO - 9.95 Anti TG - 14.8 Thank you 😊
RedOne1
in
Thyroid UK
8 months ago
Fatigue has reached a whole other level, after 10.5 years. Scared it’s narcolepsy….
Wendy x Daily: - MMF 2g Hydroxychloroquine 400mg Omeprazole Folic acid 5mg Vitamin D, a good iron supplement and magnesium - Solgar brand CBD oil at bedtime
Testosterone
Utrogestan 100mg (progesterone) Methotrexate - 20mg a week
Wendy x Daily: - MMF 2g Hydroxychloroquine 400mg Omeprazole Folic acid 5mg Vitamin D, a good iron supplement and magnesium - Solgar brand CBD oil at bedtime
Testosterone
Utrogestan 100mg (progesterone) Methotrexate - 20mg a week
Wendy39
in
LUPUS UK
1 month ago
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Newbie here.
Got no where with Endocrinology, other than low
testosterone
, treated and no difference. Most recently I've developed some Atrophy in my left calf (dominant leg) and fasciculations (tiny muscle twitches). I walk like an old man, in fact often I'm passed by many silver haired folk.
Got no where with Endocrinology, other than low
testosterone
, treated and no difference. Most recently I've developed some Atrophy in my left calf (dominant leg) and fasciculations (tiny muscle twitches). I walk like an old man, in fact often I'm passed by many silver haired folk.
Eogz
in
Myositis UK
3 months ago
dr Chris woolams
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht and now I have severe osteoporosis because my
testosterone
has never recovered I have had 1 infusion of zoledronic acid for my bones, and now I have been reading dr Chris woolams bio-chemist on canceractive that bishonates make
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht and now I have severe osteoporosis because my
testosterone
has never recovered I have had 1 infusion of zoledronic acid for my bones, and now I have been reading dr Chris woolams bio-chemist on canceractive that bishonates make
Radars
in
Advanced Prostate Cancer
8 months ago
Doubling Times and PSA acceleration - Part II
You can use the DT calculator at: https://www.mskcc.org/nomograms/prostate/psa_doubling_time Decreasing the
testosterone
levels to sub-castrate levels (T < 10 ng/dL) are the best way to stop this rapid rise in PSA over time.
You can use the DT calculator at: https://www.mskcc.org/nomograms/prostate/psa_doubling_time Decreasing the
testosterone
levels to sub-castrate levels (T < 10 ng/dL) are the best way to stop this rapid rise in PSA over time.
janebob99
in
Prostate Cancer Network
6 months ago
INSULIN TOLERANCE TEST - Low cortisol & chronic insomnia
I have low cortisol, also oestrogen and
testosterone
(despite HRT) and DHEA. I’ve had a Short Synacthen Test, which I passed as most thyroid people do. So I now know the problem doesn’t lie with the adrenals. I presume it’s with the pituitary. I have read about the insulin tolerance test.
I have low cortisol, also oestrogen and
testosterone
(despite HRT) and DHEA. I’ve had a Short Synacthen Test, which I passed as most thyroid people do. So I now know the problem doesn’t lie with the adrenals. I presume it’s with the pituitary. I have read about the insulin tolerance test.
CornishChick
in
Thyroid UK
6 months ago
TRT + Hypothyroidism Issue
Still trying to optimise the
testosterone
dose. Any ideas what I can do? Right now I'm taking Tirosint Sol (T4) 75mcg + Thybon (T3) 20mcg, upped it up to 30mcg but I don't feel any difference. edit.
Still trying to optimise the
testosterone
dose. Any ideas what I can do? Right now I'm taking Tirosint Sol (T4) 75mcg + Thybon (T3) 20mcg, upped it up to 30mcg but I don't feel any difference. edit.
greg233
in
Thyroid UK
8 months ago
High oestradiol - medicheck result. Help please !
I ordered a medi checks test to check my DHEA and
testosterone
- both incidentally look ok. Very concerned about the oestradiol result which is 1,131 - wildly high according to parameters. The fsh and lh are also out of range.
I ordered a medi checks test to check my DHEA and
testosterone
- both incidentally look ok. Very concerned about the oestradiol result which is 1,131 - wildly high according to parameters. The fsh and lh are also out of range.
Cuppppatea
in
Fertility Network UK
8 months ago
PSA Response From Broccoli Sprout Extract (Sulforaphane) May Due To Just Being Moderate ADT
Essentially, the PSA lowering effect, in my opinion, is due Sulforaphane reducing
Testosterone
and DHT levels.
Essentially, the PSA lowering effect, in my opinion, is due Sulforaphane reducing
Testosterone
and DHT levels.
jazj
in
Advanced Prostate Cancer
7 months ago
any tests for Familial hypocholesterolemia?
Possible
testosterone
deficiency but needs testing, he is following that up. Father died of stroke (details unknown), mother died from arterial burst (thought to be caused cortisol use, all arteries and veins were clear). does anyone know of GPs can test for familial hypocholesterolemia? 🌱
Possible
testosterone
deficiency but needs testing, he is following that up. Father died of stroke (details unknown), mother died from arterial burst (thought to be caused cortisol use, all arteries and veins were clear). does anyone know of GPs can test for familial hypocholesterolemia? 🌱
Regenallotment
in
Cholesterol Support
7 months ago
Does this mark the beginning of castration resistance?
Most recent PSA in April 2024 showed an PSA increase to 0.03 with
testosterone
value of 0.41 ng/ml. We have an appointment on Friday with his oncologist to discuss. My dad (and the family) is quite frightened and apprehensive that this may mark the beginning of castration resistance.
Most recent PSA in April 2024 showed an PSA increase to 0.03 with
testosterone
value of 0.41 ng/ml. We have an appointment on Friday with his oncologist to discuss. My dad (and the family) is quite frightened and apprehensive that this may mark the beginning of castration resistance.
Agh-2022
in
Advanced Prostate Cancer
4 months ago
Orgovyx: Check, Barrigel: Check, Next Up: Ray-Gunz!
After 16 weeks on Orgovyx (relugovix) my PSA: 0.71 (from 16.5) and my
Testosterone
: 25-ng/dl (from I don't know what. Normal T is 250-800 I'm told.) I want to pass on that I've been able to greatly diminish some SEs from the drug.
After 16 weeks on Orgovyx (relugovix) my PSA: 0.71 (from 16.5) and my
Testosterone
: 25-ng/dl (from I don't know what. Normal T is 250-800 I'm told.) I want to pass on that I've been able to greatly diminish some SEs from the drug.
mababa
in
Advanced Prostate Cancer
25 days ago
Well, three years in…..
points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like me, it seems. hence the name FulThrotl current regimen at UCLA: ADT - lupron + nubeqa currently approaching infusion #4 of 6 with taxotere this thursday PSA 0.06
Testosterone
points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like me, it seems. hence the name FulThrotl current regimen at UCLA: ADT - lupron + nubeqa currently approaching infusion #4 of 6 with taxotere this thursday PSA 0.06
Testosterone
FulThrotl
in
Advanced Prostate Cancer
3 months ago
BAT and Pluvicto?
BAT is simply fluctuating your
testosterone
levels to confuse the cancer. Wondering if any aspect of this would jeopardize the bonding of Pluvicto to the PSMA on the cancer cell? Thanks.
BAT is simply fluctuating your
testosterone
levels to confuse the cancer. Wondering if any aspect of this would jeopardize the bonding of Pluvicto to the PSMA on the cancer cell? Thanks.
Vinny59
in
Advanced Prostate Cancer
8 months ago
Timing of Docetaxel
Testosterone
is stable and low (0.4). ALP normal. I recently had a PET choline scan done abroad, to get another view. It showed that all my mets are in the bones.
Testosterone
is stable and low (0.4). ALP normal. I recently had a PET choline scan done abroad, to get another view. It showed that all my mets are in the bones.
Ian99
in
Advanced Prostate Cancer
4 months ago
Walsh's Folly?
I posted earlier that I had to ask ChatGPt "who came up with the 'gasoline on a fire' characterization regarding the relationship of
testosterone
and prostate cancer" and that Chat GPT had answered -- Dr. Patrick Walsh -- (father of the radical prostatectomy.)
I posted earlier that I had to ask ChatGPt "who came up with the 'gasoline on a fire' characterization regarding the relationship of
testosterone
and prostate cancer" and that Chat GPT had answered -- Dr. Patrick Walsh -- (father of the radical prostatectomy.)
VoxHope
in
Advanced Prostate Cancer
3 months ago
A little advice on latest test results
2024: TSH: 1.54 / T3: 4.1 / T4: 15.3 Ferritin: 51.7 / Folate: 31.1 / B12: 93.3 / D: 108 Aug 2024: TSH: 1.94 / T3: 3.5 / T4: 14.1 Ferritin: 68 / Folate: 21.7 / B12: 135 / D: 179 Aug 2024: Oestradiol: 272 pmol (range 82-1251 luteal phase) Progesterone: 33.70 nmol (range 13.1-46.3 luteal phase)
Testosterone
2024: TSH: 1.54 / T3: 4.1 / T4: 15.3 Ferritin: 51.7 / Folate: 31.1 / B12: 93.3 / D: 108 Aug 2024: TSH: 1.94 / T3: 3.5 / T4: 14.1 Ferritin: 68 / Folate: 21.7 / B12: 135 / D: 179 Aug 2024: Oestradiol: 272 pmol (range 82-1251 luteal phase) Progesterone: 33.70 nmol (range 13.1-46.3 luteal phase)
Testosterone
totk
in
Thyroid UK
6 days ago
Advice about recent NDT thyroid blood tests and high SHBG
0.61 Range (0.101 to 1.42) Free
Testosterone
0.00272 Range (0 to 0.02)
0.61 Range (0.101 to 1.42) Free
Testosterone
0.00272 Range (0 to 0.02)
RatherBeSleeping
in
Thyroid UK
9 months ago
Feeling dismissed on results, am I clutching at straws??
Had hormones tested at same time which showed very low estrogen and
testosterone
, but i was on low dose combined pill. Sent these to my GP and tried explaining my symptoms etc and i pretty much got laughed at and told this isnt unusual for someone my age??
Had hormones tested at same time which showed very low estrogen and
testosterone
, but i was on low dose combined pill. Sent these to my GP and tried explaining my symptoms etc and i pretty much got laughed at and told this isnt unusual for someone my age??
weedee41
in
Thyroid UK
2 months ago
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