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ESMO 2024: Opevesostat (MK-5684/ODM-208) in metastatic CRPC updated CYPIDES phase 2 results
Not bad but you need a mutation! The trial enrolled 134 heavily pre-treated mCRPC patients who had progressed after at least one novel hormonal agent and one taxane chemotherapy. Among these patients, 66 had activating mutations in the androgen receptor ligand-binding domain (AR-LBD), known to confer
Not bad but you need a mutation! The trial enrolled 134 heavily pre-treated mCRPC patients who had progressed after at least one novel hormonal agent and one taxane chemotherapy. Among these patients, 66 had activating mutations in the androgen receptor ligand-binding domain (AR-LBD), known to confer
Maxone73
in
Advanced Prostate Cancer
16 days ago
Please join us tomorrow, September 17th, for our Living Room discussion on What's New in Radiation Therapy
Hello, Please join us in our San Carlos office tomorrow Tuesday September 17th in person or if you don’t live in the area, you can join us virtually on GO2's YouTube Live channel. We are thrilled to have Dr. Daniel C. Schiffner, MD, Medical Director, Radiation Oncology Service Line Department Chair
Hello, Please join us in our San Carlos office tomorrow Tuesday September 17th in person or if you don’t live in the area, you can join us virtually on GO2's YouTube Live channel. We are thrilled to have Dr. Daniel C. Schiffner, MD, Medical Director, Radiation Oncology Service Line Department Chair
Michelezeh
Administrator
in
Lung Cancer Support
16 days ago
Generative AI tool to help with immunohistochemistry
This is a very interesting system! Thanks to Justfor_ for sending me the references. In cancer research, staining involves coloring tissues to highlight specific features under a microscope. Common techniques like H&E staining help visualize the general structure, while immunohistochemistry (IHC)
This is a very interesting system! Thanks to Justfor_ for sending me the references. In cancer research, staining involves coloring tissues to highlight specific features under a microscope. Common techniques like H&E staining help visualize the general structure, while immunohistochemistry (IHC)
Maxone73
in
Advanced Prostate Cancer
16 days ago
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Drug to fight cachexia in cancer patients phase 2 trial
seems to have good results with cachexia. Not tested directly on prostate cancer patients but could be promising. “This study showed us those who received ponsegromab had improvement in body weight, muscle mass, quality of life and physical function," https://www.upi.com/Health_News/2024/09/14/pfizer-cancer-drug-test
seems to have good results with cachexia. Not tested directly on prostate cancer patients but could be promising. “This study showed us those who received ponsegromab had improvement in body weight, muscle mass, quality of life and physical function," https://www.upi.com/Health_News/2024/09/14/pfizer-cancer-drug-test
Maxone73
in
Advanced Prostate Cancer
17 days ago
Decipher test predicts chemotherapy benefits for metastatic prostate cancer patients
Fresh for you from ESMO 2024: https://www.businesswire.com/news/home/20240915733347/en/New-Data-Presented-at-ESMO-2024-Show-that-Veracyte%E2%80%99s-Decipher-Prostate-Test-Predicts-Chemotherapy-Benefit-in-Patients-with-Metastatic-Prostate-Cancer
Fresh for you from ESMO 2024: https://www.businesswire.com/news/home/20240915733347/en/New-Data-Presented-at-ESMO-2024-Show-that-Veracyte%E2%80%99s-Decipher-Prostate-Test-Predicts-Chemotherapy-Benefit-in-Patients-with-Metastatic-Prostate-Cancer
Maxone73
in
Advanced Prostate Cancer
17 days ago
Is there anyone with experience in bladder cancer treatment?
I am 74 and in CLL remission after a 24-month course of Venetoclax plus Rituximab completed in September 2023. In July 2023 I was diagnosed with low grade, non-muscle invasive (PTa) bladder cancer and had a 12-month treatment with Epirubicin per respective protocol. Although biopsies at 3-month intervals
I am 74 and in CLL remission after a 24-month course of Venetoclax plus Rituximab completed in September 2023. In July 2023 I was diagnosed with low grade, non-muscle invasive (PTa) bladder cancer and had a 12-month treatment with Epirubicin per respective protocol. Although biopsies at 3-month intervals
RamsesII
in
CLL Support
17 days ago
KEYTRUDA Side Effects
Hi All, After failing docetaxel and pluvicto my MO put me on KEYTRUDA. Yesterday, 13 September, I experienced some very painful side effects. My neck was really stiff, which made moving it painful and difficult. The other issue was that all my joints and nerve endings felt like they were on fire. Moving
Hi All, After failing docetaxel and pluvicto my MO put me on KEYTRUDA. Yesterday, 13 September, I experienced some very painful side effects. My neck was really stiff, which made moving it painful and difficult. The other issue was that all my joints and nerve endings felt like they were on fire. Moving
MJCA
in
Advanced Prostate Cancer
18 days ago
Top Dr.s for LDR brachytherapy or SBRT
Hello everyone, I got my results on 2/28/23 , 3+4 in 3 areas. I've consulted with Dr. Dorff at City of Hope and she recommended surgery over radiation, her preference with prostate cancer. She recommended Dr. Lau if I go the surgery route. I met with Dr. Kishan at UCLA, when they had MRIdian, and
Hello everyone, I got my results on 2/28/23 , 3+4 in 3 areas. I've consulted with Dr. Dorff at City of Hope and she recommended surgery over radiation, her preference with prostate cancer. She recommended Dr. Lau if I go the surgery route. I met with Dr. Kishan at UCLA, when they had MRIdian, and
MauiJef
in
Prostate Cancer Network
19 days ago
Serous Borderine tumor
I have Serous Borderline tumor . Has anyone else got this diagnosis ? Should I be worried
I have Serous Borderline tumor . Has anyone else got this diagnosis ? Should I be worried
Kyles21
in
My Ovacome
19 days ago
Hearing loss
My upcoming AN surgery will result in permanent hearing loss in my left ear. What is the experience of living with hearing in only one ear, and has anyone had cochlear implants? How effective are they?
My upcoming AN surgery will result in permanent hearing loss in my left ear. What is the experience of living with hearing in only one ear, and has anyone had cochlear implants? How effective are they?
Ursus_thibetanus
in
Acoustic Neuroma Support
19 days ago
Dr. Selection for Proton Therapy
Hi all, I've been diagnosed with advanced prostate cancer. Gleason 9 with metastatic to the right seminal vessel and one lymph node. Currently getting registered at Loma Linda and also the Proton Center at San Diego. Dr. Rossi just went on vacation for a month, so he's unfortunately a no-go, and I'm
Hi all, I've been diagnosed with advanced prostate cancer. Gleason 9 with metastatic to the right seminal vessel and one lymph node. Currently getting registered at Loma Linda and also the Proton Center at San Diego. Dr. Rossi just went on vacation for a month, so he's unfortunately a no-go, and I'm
Garfield-_1234
in
Advanced Prostate Cancer
20 days ago
GCA Training in Scanning at Leeds
I took part in this training yesterday as a volunteer 'patient'. It was interesting seeing how different doctors managed, or had difficulty, practicing scanning on me. I was lucky that the tutor in my room was Prof Dasgupta. 3 trainees at a time and 3 groups over 1.5 hours, quite intensive. I picked
I took part in this training yesterday as a volunteer 'patient'. It was interesting seeing how different doctors managed, or had difficulty, practicing scanning on me. I was lucky that the tutor in my room was Prof Dasgupta. 3 trainees at a time and 3 groups over 1.5 hours, quite intensive. I picked
PastelsinArt
in
PMRGCAuk
20 days ago
Longer side effects after Enhertu infusion
I have been on Enhertu for over a year but my last two infusions are causing longer periods of nausea and fatigue .It was only for two days after the pre meds wore off.This time it has been a full week.Anyone else notice this? I wonder if my Enhertu has run it's course because that was what I experienced
I have been on Enhertu for over a year but my last two infusions are causing longer periods of nausea and fatigue .It was only for two days after the pre meds wore off.This time it has been a full week.Anyone else notice this? I wonder if my Enhertu has run it's course because that was what I experienced
Figletf
in
SHARE Metastatic Breast Cancer
20 days ago
heading for salvage therapy
hello all. Well my last two ( three month) PSA tests were 0.10 and MO. And RO. Recommend somewhat early salvage radiation treatment. A question I would like some input on is should I look into proton therapy over IMRT. I would need to travel to Fred hutch or Salt Lake City as I live in Reno Nv. Just
hello all. Well my last two ( three month) PSA tests were 0.10 and MO. And RO. Recommend somewhat early salvage radiation treatment. A question I would like some input on is should I look into proton therapy over IMRT. I would need to travel to Fred hutch or Salt Lake City as I live in Reno Nv. Just
Elkguide
in
Advanced Prostate Cancer
20 days ago
When did you feel some hope you might pull out of this and not die next week?
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
New diagnosis. What i thought was back pain just turned out to be Advanced Metastatic PROSTATE Cancer on a CT Scan with contrast and PSA of 56. I've been blessed with excellent health til now. This is all scary NEW to me and my wife, we are in shock. Oncologist/Urologist ordered a ultrasound guided
ELOfan
in
Advanced Prostate Cancer
20 days ago
Frustrating Appointment
Good Morning All I hope you don't mind if I vent here as I know others have experienced the same sort of thing but I just had a very frustrating appointment with my haematology department. I have PV, diagnosed in Jan 2017, been on aspirin for years and interferon for nearly 14 months. I mostly
Good Morning All I hope you don't mind if I vent here as I know others have experienced the same sort of thing but I just had a very frustrating appointment with my haematology department. I have PV, diagnosed in Jan 2017, been on aspirin for years and interferon for nearly 14 months. I mostly
Skyehope
in
MPN Voice
20 days ago
Hypermetabolic PET results
Hi everyone...God bless you all in this fight. I have only posted once before, I think. But, sure do keep up with all on this board...so helpful!I have triple pos MBC with Pik3ca mutation. Diagnosed about 2 1/2 years ago. Not much luck with treatments...am on my 4th or 5th line...have lost count. My
Hi everyone...God bless you all in this fight. I have only posted once before, I think. But, sure do keep up with all on this board...so helpful!I have triple pos MBC with Pik3ca mutation. Diagnosed about 2 1/2 years ago. Not much luck with treatments...am on my 4th or 5th line...have lost count. My
Tuckermom
in
SHARE Metastatic Breast Cancer
20 days ago
efudex ( fluorouracil 5)
My dermatologist has suggested and prescribed the above medications for my face and neck for my ongoing battle with actinic keratosis and squamous cell carcinoma ( 6 mohs surgeries). Has anybody used this treatment for their skin? From what I read, it is a topical chemotherapy. It causes redness,
My dermatologist has suggested and prescribed the above medications for my face and neck for my ongoing battle with actinic keratosis and squamous cell carcinoma ( 6 mohs surgeries). Has anybody used this treatment for their skin? From what I read, it is a topical chemotherapy. It causes redness,
Claybuster
in
CLL Support
21 days ago
In vivo/vitro latest immunotherapy proof of concept by targeting IL30 in prostate cancer
Meanwhile in Italy, a group of researchers....this study discusses the development of immunoliposome-based CRISPR/Cas9 delivery targeting IL30 in prostate cancer. In vivo and in vitro it showed great results in inhibiting tumor growth and metastasis formation. Alteration of tumor environment (reduced
Meanwhile in Italy, a group of researchers....this study discusses the development of immunoliposome-based CRISPR/Cas9 delivery targeting IL30 in prostate cancer. In vivo and in vitro it showed great results in inhibiting tumor growth and metastasis formation. Alteration of tumor environment (reduced
Maxone73
in
Advanced Prostate Cancer
21 days ago
Hysterectomy combined with pelvic floor repair - Booked - will symptoms be similar to Zoladex - advice needed!!!
Hi guys, I'm 36 and have been on zoladex for the past 9 months. I've made the decision to have a hysterectomy along with recommend pelvic floor repair. I was wondering if anyone out there had been on zoladex before their hysterectomy and if the menopause symptoms where similar after or worse? Im
Hi guys, I'm 36 and have been on zoladex for the past 9 months. I've made the decision to have a hysterectomy along with recommend pelvic floor repair. I was wondering if anyone out there had been on zoladex before their hysterectomy and if the menopause symptoms where similar after or worse? Im
Sunshineriverpaella
in
Endometriosis UK
21 days ago
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