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Experiences with
Prostate-specific antigen (PSA)
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Concern about having more radiation to prostate after 43 external beam treatments 15 years ago
15 years ago my husband had 43 radiation treatments after
PSA
reached 50 & his 3rd biopsy showed 1 core to have cancer., Gleason was 3-3. He has had Lupron injections since then.
15 years ago my husband had 43 radiation treatments after
PSA
reached 50 & his 3rd biopsy showed 1 core to have cancer., Gleason was 3-3. He has had Lupron injections since then.
Pickleball38
in
Advanced Prostate Cancer
4 months ago
Estrogen for Bone Health in PCa patient.
Gleason 9-10 when detected with 250
PSA
. Pet CT showed all contained in prostrate but with one ECE and seminal vesicles involvement. No spread visible to lymph nodes or anywhere in the body.
Gleason 9-10 when detected with 250
PSA
. Pet CT showed all contained in prostrate but with one ECE and seminal vesicles involvement. No spread visible to lymph nodes or anywhere in the body.
binati
in
Advanced Prostate Cancer
1 month ago
Testosterone too high?
I recently had my quarterly
PSA
and T tests, following stopping 18 months of ADT (Orgovyx) in April of 2022.
PSA
continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706.
I recently had my quarterly
PSA
and T tests, following stopping 18 months of ADT (Orgovyx) in April of 2022.
PSA
continued to de undetectable (<0.01) and T was 761. The last quarterly T was 706.
JPnSD
in
Advanced Prostate Cancer
6 months ago
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Castration by Estrogen Patch
This plot shows a dramatic decrease in testosterone and
PSA
after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
This plot shows a dramatic decrease in testosterone and
PSA
after starting estrogen patch therapy, indicating that transdermal estrogen (TDE) therapy effectively castrates men, and with fewer side effects than Lupron ADT.
janebob99
in
Prostate Cancer Network
5 months ago
Taking vacation from meds bad idea?
I am polymetastatic with the usual side effects and my
PSA
is undetectable. Anyone know what the science says about taking a break from the medications? Good idea? Bad idea? Is there any real evidence to prove either way? First time poster however I have been following for a while.
I am polymetastatic with the usual side effects and my
PSA
is undetectable. Anyone know what the science says about taking a break from the medications? Good idea? Bad idea? Is there any real evidence to prove either way? First time poster however I have been following for a while.
Vostiniotis
in
Advanced Prostate Cancer
2 months ago
first timer
just received diagnosis mets to bone 3wks ago. i am on xtandi and orgovyx the
psa
droped from 70 to 4.6 after 2wks. any thoughts?
just received diagnosis mets to bone 3wks ago. i am on xtandi and orgovyx the
psa
droped from 70 to 4.6 after 2wks. any thoughts?
billsfan
in
Advanced Prostate Cancer
5 months ago
0.04 PSA
Well after over a year of undetected my
PSA
has risen to 0.04. I will meet with oncology in a few weeks to discuss next steps. Perhaps a scan.
Well after over a year of undetected my
PSA
has risen to 0.04. I will meet with oncology in a few weeks to discuss next steps. Perhaps a scan.
Howard53545
in
Advanced Prostate Cancer
7 months ago
EORTC GUCG 2238 De-escalate: A pragmatic trial to revisit intermittent androgen-deprivation therapy: will we know something more soon?
"The primary goal of this academic-led, open-label, multicenter, pragmatic, randomized phase III study is to investigate whether intermittent maximum androgen blockade (iMAB) can be safely administered to mHNPC patients who reached a
PSA
≤ 0.2 ng/mL at 6-12 months of continuous treatment (cMAB), as compared
"The primary goal of this academic-led, open-label, multicenter, pragmatic, randomized phase III study is to investigate whether intermittent maximum androgen blockade (iMAB) can be safely administered to mHNPC patients who reached a
PSA
≤ 0.2 ng/mL at 6-12 months of continuous treatment (cMAB), as compared
Maxone73
in
Advanced Prostate Cancer
2 months ago
Pluvicto patient
74 yo male 3rd round of pluvicto
PSA
started at 9.8 down to 1.41 !! Been on Luprone for 18 months! Prostrate has been removed and cancer has spread to liver and spine. Surprisingly I feel good, no pain yet! I am a farmer still going 12 hours a day!
74 yo male 3rd round of pluvicto
PSA
started at 9.8 down to 1.41 !! Been on Luprone for 18 months! Prostrate has been removed and cancer has spread to liver and spine. Surprisingly I feel good, no pain yet! I am a farmer still going 12 hours a day!
Reltubs
in
Advanced Prostate Cancer
2 months ago
How long on Prostap?
Gleeson 4+3 but
PSA
only ever up to 10. I have had four PSMA scans which show 8 metastases in skull, ribs, pubic bone, hip bone. These continue to grow. I have been on Aberiterone/prednisolone, plus Prostap every 3 months.
Gleeson 4+3 but
PSA
only ever up to 10. I have had four PSMA scans which show 8 metastases in skull, ribs, pubic bone, hip bone. These continue to grow. I have been on Aberiterone/prednisolone, plus Prostap every 3 months.
Stephen399b
in
Advanced Prostate Cancer
4 months ago
Dental Issues on Finesteride
I'll keep having my
PSA
monitored every 3 months. Any thoughts on how my
PSA
is rising without scans showing activity?
I'll keep having my
PSA
monitored every 3 months. Any thoughts on how my
PSA
is rising without scans showing activity?
fast_eddie
in
Fight Prostate Cancer
6 months ago
Rise in Testosterone but not PSA?
He got some blood work today, and his
is still .06 but his testosterone has risen to 34. Is this a cause for concern? Also, it looks like anemia might be a new thing, low hemoglobin. Does this mean that the ADP isn't working anymore even though the
PSA
is down?
He got some blood work today, and his
is still .06 but his testosterone has risen to 34. Is this a cause for concern? Also, it looks like anemia might be a new thing, low hemoglobin. Does this mean that the ADP isn't working anymore even though the
PSA
is down?
ThisIsForMyMom
in
Advanced Prostate Cancer
6 months ago
What comes after, what comes next?
Stage 4, mets to 8+ bones at time of diagnosis,
PSA
at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s
PSA
dropped from 2.47-1.46 and pain has been improving.
Stage 4, mets to 8+ bones at time of diagnosis,
PSA
at 137 (10/22.) Lupron twice a year, Bicalutamide, failed at 7 months, Xtandi failed at 4 months, currently on Zytiga. We met with my dad’s oncologist on 4/24. My Dad’s
PSA
dropped from 2.47-1.46 and pain has been improving.
lgutman
in
Advanced Prostate Cancer
2 months ago
Chemo or no/not yet?
PSA
hit 366 before starting Abiraterone and Degarelix. Start Lupron next week. Negative on DNA test. Will see what
PSA
looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude towards it.
PSA
hit 366 before starting Abiraterone and Degarelix. Start Lupron next week. Negative on DNA test. Will see what
PSA
looks like next week after a month of ADT. My question chemo, no chemo or wait on chemo? Onco and Rad Onco both seemed to have a very soft attitude towards it.
4tunate1
in
Advanced Prostate Cancer
4 months ago
BILLY NEEDS HELP
my
psa
was 11.7 last week, the highest in my life. I have been off all drugs for two months now. I think I should start a combination of two drugs immediately and Not go backwards on Lupron again.
my
psa
was 11.7 last week, the highest in my life. I have been off all drugs for two months now. I think I should start a combination of two drugs immediately and Not go backwards on Lupron again.
billyboy3
in
Advanced Prostate Cancer
3 months ago
primary tumor
Last
PSA
was .1. The nodules and lymph nodes are gone and I was turned down for radiation to the prostate. My diet is beyond clean, never thought I could do it, but I eat most raw vegatables, berries, nuts and beans. Fish if it's fresh. Nice to you all
Last
PSA
was .1. The nodules and lymph nodes are gone and I was turned down for radiation to the prostate. My diet is beyond clean, never thought I could do it, but I eat most raw vegatables, berries, nuts and beans. Fish if it's fresh. Nice to you all
muttonman
in
Advanced Prostate Cancer
5 days ago
Darolutamide 1200mg/day?
My
PSA
was 6.4 & was reduced to 2.4 in 5 weeks. So that is good, but my question is, has anyone here been on that amount of Darolutamide a day? & What is it doing to the heart? not to mention liver & kidneys. My suspicions were raised because now they subject me to blood pressure tests.
My
PSA
was 6.4 & was reduced to 2.4 in 5 weeks. So that is good, but my question is, has anyone here been on that amount of Darolutamide a day? & What is it doing to the heart? not to mention liver & kidneys. My suspicions were raised because now they subject me to blood pressure tests.
ARIES29
in
Advanced Prostate Cancer
8 days ago
Dutssteride increases PSA Doubling Time by 2X for men with PSA Failure.
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
Failure. In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X).
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
Failure. In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X).
janebob99
in
Prostate Cancer Network
4 months ago
PSA going down, but ALP increasing
At 2 weeks, my
PSA
had dropped from 133 to 66! Bone pain is much less. All my liver numbers are fine, but alkaline phosphatase has gone from 199 when I started to 429 at two weeks and 519 at three weeks. Doc thinks may just be a surge, but this is a pretty big surge. Any thoughts?
At 2 weeks, my
PSA
had dropped from 133 to 66! Bone pain is much less. All my liver numbers are fine, but alkaline phosphatase has gone from 199 when I started to 429 at two weeks and 519 at three weeks. Doc thinks may just be a surge, but this is a pretty big surge. Any thoughts?
rsgdmd
in
Advanced Prostate Cancer
3 months ago
pluvicto
My
PSA
went from 10 to22 after the first round. Today after the second round it dropped to 15. Anyone else have a jump after the first treatment and then continued to decline for the remaining treatments.
My
PSA
went from 10 to22 after the first round. Today after the second round it dropped to 15. Anyone else have a jump after the first treatment and then continued to decline for the remaining treatments.
diatom
in
Advanced Prostate Cancer
23 days ago
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