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Autovaccination seems a hot topic lately: Mt. Sinai autovaccination technique to turn cold prostate cancer hot (Phase 1)
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
Maxone73
in
Advanced Prostate Cancer
2 months ago
Are endocrinologists of any help after ADT?
After ADT, my MO told me that handling things like Prolia management won't be in her bailiwick. I didn't ask about post-ADT SE's and recovery from same. Hot flashes, low T, BMD loss, and last not least sarcopenia. What is the community's experience with how post-treatment SE's are best handled? Are
After ADT, my MO told me that handling things like Prolia management won't be in her bailiwick. I didn't ask about post-ADT SE's and recovery from same. Hot flashes, low T, BMD loss, and last not least sarcopenia. What is the community's experience with how post-treatment SE's are best handled? Are
Derf4223
in
Advanced Prostate Cancer
2 months ago
Podcast Episode with Abraham Morgentaler, MD about Testosterone and Prostate Cancer
This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Casperson. She often explores misconceptions about hormones. This episode with Dr. Morgentaler takes a fascinating look at the theories about castration and prostate cancer. Spoiler alert: it may shake your confidence in the
This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Casperson. She often explores misconceptions about hormones. This episode with Dr. Morgentaler takes a fascinating look at the theories about castration and prostate cancer. Spoiler alert: it may shake your confidence in the
Chris_Ali
in
Advanced Prostate Cancer
2 months ago
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LaRue44
My husband has metastatic prostate cancer. We went through all the treatments including 5 pluvicto treatments. Even though his scan shows improvement in some areas it continues to spread. Maybe this is due to no meds such as Xtandi to stop the spread. I'm trying to get more information by reading people's
My husband has metastatic prostate cancer. We went through all the treatments including 5 pluvicto treatments. Even though his scan shows improvement in some areas it continues to spread. Maybe this is due to no meds such as Xtandi to stop the spread. I'm trying to get more information by reading people's
LaRue44
in
Advanced Prostate Cancer
2 months ago
Robotic wedge lung resection
During my pet scan a lung shadow was reported. Biopsy failed to get tissue but Drs. do not think it is from the stage 2/3 prostate cancer. They recommend a wedge resection via a daVinci mechanism to remove it. I'd like to hear from someone who has had that surgery but since it may be tangential to this
During my pet scan a lung shadow was reported. Biopsy failed to get tissue but Drs. do not think it is from the stage 2/3 prostate cancer. They recommend a wedge resection via a daVinci mechanism to remove it. I'd like to hear from someone who has had that surgery but since it may be tangential to this
Eadgbe
in
Advanced Prostate Cancer
3 months ago
How about eating a healthy snack that might help fight PCa. Lotus seeds (Nelumbo nucifera) also known as makhana contain Neferine, see below
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation Suat Erdogan, Kader Turkekul First published: 11 May 2020 https://doi.org/10.1111/jfbc.13253 Abstract Cancer stem cells (CSCs) are one of the significant causes of cancer treatment failure
Neferine inhibits proliferation and migration of human prostate cancer stem cells through p38 MAPK/JNK activation Suat Erdogan, Kader Turkekul First published: 11 May 2020 https://doi.org/10.1111/jfbc.13253 Abstract Cancer stem cells (CSCs) are one of the significant causes of cancer treatment failure
Graham49
in
Advanced Prostate Cancer
3 months ago
The suppression of Prolactin is required for the treatment of advanced prostate cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641560/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641560/
agnut
in
Fight Prostate Cancer
3 months ago
Bad news: prostate cancers doubling by 2040
Bad news on one side, for all the guys that will join the damn club (and the trends say their age is lowering as well....I am an example actually!). On the other side we can hope for an increase of effort to solve the problem, at least for prostate, breast, lung and colorectal cancers, which are quite
Bad news on one side, for all the guys that will join the damn club (and the trends say their age is lowering as well....I am an example actually!). On the other side we can hope for an increase of effort to solve the problem, at least for prostate, breast, lung and colorectal cancers, which are quite
Maxone73
in
Advanced Prostate Cancer
3 months ago
Not PCa related but sounds like a very promising approach
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
When I read "advanced pancreatic cancer" and "overall disease control of 94%" in the same document...I feel like smiling.... https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-gene-therapy-plus-chemotherapy/
Maxone73
in
Advanced Prostate Cancer
3 months ago
Zytiga vs Nubeqa for Triple Therapy
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
Hi, I've recently received a diagnosis of Stage 4 prostate cancer, which is high volume and hormone-sensitive. I've consulted with 3 oncologist and all recommend triple therapy: Lupron alongside 6 rounds of Docetaxel, plus an ARPI. While two oncologists recommend Nubeqa, one strongly advocates for Zytiga
littleCar
in
Advanced Prostate Cancer
3 months ago
Prostate cancer cases worldwide likely to double by 2040, analysis finds
Hopefully this report leads to more investment in treatment . "The number of men diagnosed with prostate cancer worldwide is projected to double to 2.9 million a year by 2040, with annual deaths predicted to rise by 85%, according to the largest study of its kind. " "Prostate cancer is already a
Hopefully this report leads to more investment in treatment . "The number of men diagnosed with prostate cancer worldwide is projected to double to 2.9 million a year by 2040, with annual deaths predicted to rise by 85%, according to the largest study of its kind. " "Prostate cancer is already a
PSAed
in
Advanced Prostate Cancer
3 months ago
Why don't doctors prescribe Dutasteride more often?
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
I get this question from a lot of men that have prostate cancer. Although the black label warning is a concern to some doctors, and has been discussed here in previous posts, I think the main reason is simply that most doctors don't know about it. Here is the single best paper reviewing the three major
janebob99
in
Prostate Cancer Network
3 months ago
PSMA Scans and False Positives
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
So I saw my MO yesterday to review my ongoing treatment of Xtandi and Lupron. Been 3 months so far with no real side effects except hot flashes. My PSMA scan showed prostate and one met to sacrum. Prostate treated with 28 rounds of EBRT. MO says since sacrum is so close to prostrate it might have
Jeffdanger
in
Advanced Prostate Cancer
3 months ago
Reaction to docetaxel twice now.
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
second cycle of docetaxel and the same reaction. Pelvic pain, flushing, muzzy head and head ache. Great response from the team again and feeling better pretty quickly. Last time they tried again and it went through okay. Had meds to mitigate but not prevented a reaction. They aren’t go to try the infusion
FortyWinks
in
Advanced Prostate Cancer
3 months ago
Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
3 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
3 months ago
My Prostate Cancer Journey
It has been a year since I was diagnosed with prostate cancer, and it has been quite a difficult journey. However, I have been incredibly fortunate to have the love and support of my wife and family every step of the way. Their presence has been a source of immense emotional comfort and personal care
It has been a year since I was diagnosed with prostate cancer, and it has been quite a difficult journey. However, I have been incredibly fortunate to have the love and support of my wife and family every step of the way. Their presence has been a source of immense emotional comfort and personal care
davidjroberts
in
Advanced Prostate Cancer
3 months ago
Platelets Dropping
Is this “normal” or any advice? Undergoing radiation since March, have 22 sessions done, 6 to go. Started Casodex in December to prepare to start Eligard in January. Radiation started in March. My platelets have been dropping. MO said could be due to Lupron and/or radiation. IMRT targets Gleason 9
Is this “normal” or any advice? Undergoing radiation since March, have 22 sessions done, 6 to go. Started Casodex in December to prepare to start Eligard in January. Radiation started in March. My platelets have been dropping. MO said could be due to Lupron and/or radiation. IMRT targets Gleason 9
Hope49823
in
Advanced Prostate Cancer
3 months ago
I need urgent help for my uncle.
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
3 months ago
I need urgent help for my uncle
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
3 months ago
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