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Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
2 months ago
Addition of an ARSI to standard ADT significantly increases the risk of fractures and falls in men with prostate cancer
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Jones C, Gray S, Brown M, et al. Risk of fractures and falls in men with advanced or metastatic prostate cancer receiving androgen deprivation therapy and treated with novel androgen receptor signalling inhibitors: a systematic review and meta-analysis of randomised controlled trials. Eur Urol Oncol.
Graham49
in
Advanced Prostate Cancer
2 months ago
My Prostate Cancer Journey
It has been a year since I was diagnosed with prostate cancer, and it has been quite a difficult journey. However, I have been incredibly fortunate to have the love and support of my wife and family every step of the way. Their presence has been a source of immense emotional comfort and personal care
It has been a year since I was diagnosed with prostate cancer, and it has been quite a difficult journey. However, I have been incredibly fortunate to have the love and support of my wife and family every step of the way. Their presence has been a source of immense emotional comfort and personal care
davidjroberts
in
Advanced Prostate Cancer
3 months ago
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Platelets Dropping
Is this “normal” or any advice? Undergoing radiation since March, have 22 sessions done, 6 to go. Started Casodex in December to prepare to start Eligard in January. Radiation started in March. My platelets have been dropping. MO said could be due to Lupron and/or radiation. IMRT targets Gleason 9
Is this “normal” or any advice? Undergoing radiation since March, have 22 sessions done, 6 to go. Started Casodex in December to prepare to start Eligard in January. Radiation started in March. My platelets have been dropping. MO said could be due to Lupron and/or radiation. IMRT targets Gleason 9
Hope49823
in
Advanced Prostate Cancer
3 months ago
I need urgent help for my uncle.
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
3 months ago
I need urgent help for my uncle
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
My uncle who resides in France and is a holder of a French citizenship, has been diagnosed with terminal prostatic cancer. He had treated this condition in the past but it ultimately came back, but this time around doctors (including a specialist in Marseille) made him know that his condition was incurable
Admhdu
in
Advanced Prostate Cancer
3 months ago
chemo
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
has anyone who failed xtandi and zytiga have good outcome with chemo- does it completely eliminate the cancer or do you still have to take things after - how does it work when it stops - also can you take it in smaller doses?
Chris52981
in
Advanced Prostate Cancer
3 months ago
Improved Posts and Replies
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Darryl
Partner
in
Advanced Prostate Cancer
3 months ago
Satisfaction with AUS after Radiation
If you have had an AUS implanted after receiving radiation are you satisfied with your decision and has it improved your quality of life? Or do you regret having an AUS implanted and if so why? I have had both a prostatectomy and salvage radiation (see profile). I regained continence after the prostatectomy
If you have had an AUS implanted after receiving radiation are you satisfied with your decision and has it improved your quality of life? Or do you regret having an AUS implanted and if so why? I have had both a prostatectomy and salvage radiation (see profile). I regained continence after the prostatectomy
Alturia
in
Advanced Prostate Cancer
3 months ago
Prostap delayed
How long after stopping Prostap did you symptoms/periods come back? My next injection was postponed due to the strike and was wondering what effect this would have. I’ve managed to get an appointment for a weeks time.
How long after stopping Prostap did you symptoms/periods come back? My next injection was postponed due to the strike and was wondering what effect this would have. I’ve managed to get an appointment for a weeks time.
Strictly2010
in
Endometriosis UK
1 year ago
SBRT process just starting
Hello and THANK YOU to all you brave and extremely knowledgeable folks for posting your priceless experiences and expertise here and to the brave spouses and partners as well. This Network has helped keep me sane since I was diagnosed with PC in 2023 and I could not decide on which way to deal with
Hello and THANK YOU to all you brave and extremely knowledgeable folks for posting your priceless experiences and expertise here and to the brave spouses and partners as well. This Network has helped keep me sane since I was diagnosed with PC in 2023 and I could not decide on which way to deal with
Info_Search_JMA
in
Prostate Cancer Network
3 months ago
Second Line Hormonal
I am still only receiving Zoladex injections every three months. I did try Abiraterone 2022/2023 and it failed after a few months. I have been trying to get my Oncologist to prescribe Enzalutamide. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug
I am still only receiving Zoladex injections every three months. I did try Abiraterone 2022/2023 and it failed after a few months. I have been trying to get my Oncologist to prescribe Enzalutamide. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug
Islandboy2021
in
Advanced Prostate Cancer
3 months ago
IMRT WITHOUT THE JELL
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
woppaginny
in
Advanced Prostate Cancer
3 months ago
Cabazitaxel Questions
I have switched from Docetaxel to Cabazitaxel. Should I still take the Grastofil injections?
I have switched from Docetaxel to Cabazitaxel. Should I still take the Grastofil injections?
Islandboy2021
in
Advanced Prostate Cancer
3 months ago
Curious about Prednisone dosage.
Warriors If you do not mind telling me, I am curious about how many of you on Zytiga/Abiraterone take a 5 mg dosage of Prednisone , and how many take some other dosage level. I know most of your also getting Lupron injections and some are taking other medications along with the Zytiga/Abiraterone
Warriors If you do not mind telling me, I am curious about how many of you on Zytiga/Abiraterone take a 5 mg dosage of Prednisone , and how many take some other dosage level. I know most of your also getting Lupron injections and some are taking other medications along with the Zytiga/Abiraterone
85236442968
in
Advanced Prostate Cancer
3 months ago
Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
3 months ago
Eligard injection site
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
Lslal
in
Advanced Prostate Cancer
3 months ago
Using Enzalutamide, Darolutamide, Apalutamide only.
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
dhccpa
in
Prostate Cancer Network
3 months ago
Update on failing Enzalutamide
Hello again friends, I wrote recently after learning that Xtandi was no longer working, seeking options. Since then I have had a consultation with my Oncologist and we went through the (limited) range of options for someone who is living in the UK and being treated on the National Health Service. Brief
Hello again friends, I wrote recently after learning that Xtandi was no longer working, seeking options. Since then I have had a consultation with my Oncologist and we went through the (limited) range of options for someone who is living in the UK and being treated on the National Health Service. Brief
CrocodileShoes
in
Advanced Prostate Cancer
11 months ago
Dutasteride Black Box Warning Label is Inappropriate.
This plot that I made goes back to the original paper by Thompson et al. (2003), that was the basis for slapping the Black Box Warning Label on Dutasteride prescriptions. https://pubmed.ncbi.nlm.nih.gov/12824459/ There are some important points that should be considered: (1) Thompson only studied
This plot that I made goes back to the original paper by Thompson et al. (2003), that was the basis for slapping the Black Box Warning Label on Dutasteride prescriptions. https://pubmed.ncbi.nlm.nih.gov/12824459/ There are some important points that should be considered: (1) Thompson only studied
janebob99
in
Prostate Cancer Network
3 months ago
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