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Considering Rapamycin
Rapamycin (aka Sirolimus) is a very interesting drug of diverse effects. It is being explored in early trials for PC because of positive effects demonstrated in cell cultures of PC cell lines and in animal model (mice). A phase I dosing study in human PC patients demonstrated a safe profile in moderate
Rapamycin (aka Sirolimus) is a very interesting drug of diverse effects. It is being explored in early trials for PC because of positive effects demonstrated in cell cultures of PC cell lines and in animal model (mice). A phase I dosing study in human PC patients demonstrated a safe profile in moderate
MateoBeach
in
Advanced Prostate Cancer
3 years ago
Random Twitches
Hi all, When I was first diagnosed with RLS a few years back, I was also sent on a sleep study which showed I suffer from PLMS in the night too. However, over the last month or two, I have been getting random twitches in my hands, legs and arms (mostly on the left side). I always assumed that PLMS
Hi all, When I was first diagnosed with RLS a few years back, I was also sent on a sleep study which showed I suffer from PLMS in the night too. However, over the last month or two, I have been getting random twitches in my hands, legs and arms (mostly on the left side). I always assumed that PLMS
Keaney27
in
Restless Legs Syndrome
3 years ago
Enlarged dilated pupils
Had a very scary episode yesterday two hours after taking my meds (1/2 senemit and eighth of tsp 99% mucuna) Started with blurred vision like there was grey smoke in the room. My pupils dilated so large as if I was a junkie. This lasted for about 4 hrs. Felt otherwise normal (apart from freaking out
Had a very scary episode yesterday two hours after taking my meds (1/2 senemit and eighth of tsp 99% mucuna) Started with blurred vision like there was grey smoke in the room. My pupils dilated so large as if I was a junkie. This lasted for about 4 hrs. Felt otherwise normal (apart from freaking out
saraoutwest
in
Cure Parkinson's
3 years ago
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Another Rejection
and I stupidly answered I was diagnosed with Borderline
Personality
Disorder
over a decade ago. I was looking for help both for myself and for my daughter. The moment I shared my diagnosis the entire tone of the call changed. The man on the other end quickly started backtracking his availability.
and I stupidly answered I was diagnosed with Borderline
Personality
Disorder
over a decade ago. I was looking for help both for myself and for my daughter. The moment I shared my diagnosis the entire tone of the call changed. The man on the other end quickly started backtracking his availability.
blondethunder39
in
Anxiety and Depression Support
3 years ago
A living nightmare
I've been having belly problems for many years, in 2020 I was diagnosed with Ibs I been on medication ever since. Nothing changed in fact it's getting worse I got an appointment today at special clinic, I don't know why or what for. I'm worried this is C. Hoping special clinic will do camera, but I
I've been having belly problems for many years, in 2020 I was diagnosed with Ibs I been on medication ever since. Nothing changed in fact it's getting worse I got an appointment today at special clinic, I don't know why or what for. I'm worried this is C. Hoping special clinic will do camera, but I
Rissa86
in
IBS Network
3 years ago
Intro
Hey everyone im new, however; I'm Struggling with anxiety and depression and i'm also bipolar. I have been struggling with these things most of my life. I was recently released from prison in 2018. I also struggle with codependency. Since being released and trying to get my life back on track things
Hey everyone im new, however; I'm Struggling with anxiety and depression and i'm also bipolar. I have been struggling with these things most of my life. I was recently released from prison in 2018. I also struggle with codependency. Since being released and trying to get my life back on track things
BriannaC
in
Anxiety and Depression Support
3 years ago
Psychotic Break Down’s.
Hi, I’m wondering If Psychotic Break Down’s can come From Anxiety Or PTSD?
Hi, I’m wondering If Psychotic Break Down’s can come From Anxiety Or PTSD?
nkotbjoeymc
in
Anxiety Support
3 years ago
Took Crinone (vag) mistakenly instead of Progynova (vag
Hi everyone, I need you advise and guidance desperately :(. I started today with medication prep for FET and I took the first dose of Progynova orally at 9am but as medications had not arrived yet, I managed all in panic to open the med package and take quickly at 11:30 one dose of Crinone pessary (
Hi everyone, I need you advise and guidance desperately :(. I started today with medication prep for FET and I took the first dose of Progynova orally at 9am but as medications had not arrived yet, I managed all in panic to open the med package and take quickly at 11:30 one dose of Crinone pessary (
ValaI
in
Fertility Network UK
3 years ago
RLS, pramapexole and weight gain
Has anyone gained weight since having rls. I think its the meds-pramapexole mostly and oxycodone. I am constantly eating at night. Sometimes I think I have no control.
Has anyone gained weight since having rls. I think its the meds-pramapexole mostly and oxycodone. I am constantly eating at night. Sometimes I think I have no control.
lorri214
in
Restless Legs Syndrome
3 years ago
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy 2021
So I take Niacin 250 mg time released per the Augusta study to reduce inflammation through binding to the GPR109A https://www.researchgate.net/publication/352486597_Niacin_Enhancement_for_Parkinson's_Disease_An_Effectiveness_Trial. NAD+ is disrupted in PD patients "Progresses in both basic research and
So I take Niacin 250 mg time released per the Augusta study to reduce inflammation through binding to the GPR109A https://www.researchgate.net/publication/352486597_Niacin_Enhancement_for_Parkinson's_Disease_An_Effectiveness_Trial. NAD+ is disrupted in PD patients "Progresses in both basic research and
Bolt_Upright
in
Cure Parkinson's
3 years ago
Is it normal?
I was diagnosed with ptsd, is it normal even if you aren’t in the military or never been to have ptsd?
I was diagnosed with ptsd, is it normal even if you aren’t in the military or never been to have ptsd?
Miakinz188
in
Heal My PTSD
3 years ago
Denied treatment for severe depression and Bipolar Disorder by local NHS CMHT
Hi All, I live in the UK and have been diagnosed with both Major depressive disorder, and Bipolar Disorder since age 18 when I was forced to leave University due to depression. I am interested in anyone else in the UK who has been told by their local Community mental health team that they are now not
Hi All, I live in the UK and have been diagnosed with both Major depressive disorder, and Bipolar Disorder since age 18 when I was forced to leave University due to depression. I am interested in anyone else in the UK who has been told by their local Community mental health team that they are now not
HangTough
in
Mental Health Support
3 years ago
Anger or Mania
I’ve been diagnosed with bipolar 1 with psychosis and anxiety and depression etc I was wondering if episodes of extreme heightened anger and impulsivity is mania? 🤔 Having a hard time accepting my diagnosis 🤷🏻♀️
I’ve been diagnosed with bipolar 1 with psychosis and anxiety and depression etc I was wondering if episodes of extreme heightened anger and impulsivity is mania? 🤔 Having a hard time accepting my diagnosis 🤷🏻♀️
Maverick319
in
Anxiety and Depression Support
3 years ago
Do I HAVE ADHD?
ADHD : something that I think I have. I’m going to see a neurologist tomorrow to see if I can get some kind of testing To narrow down what exactly is going on with my brain because within the last year I have experienced so many symptoms like constantly running late misplacing things losing things
ADHD : something that I think I have. I’m going to see a neurologist tomorrow to see if I can get some kind of testing To narrow down what exactly is going on with my brain because within the last year I have experienced so many symptoms like constantly running late misplacing things losing things
Heaven46
in
Mental Health Support
3 years ago
BPD
Does anyone here have BPD (borderline
personality
disorder
)?
Does anyone here have BPD (borderline
personality
disorder
)?
Organiker
in
Mental Health Support
3 years ago
Penile Injection Therapy
I notice none of these medications are listed in Goodrx. Does anyone know how much they cost? What some of the plusses and minuses are in their use? "The three main types of medications used in penile injection therapy include: papaverine phentolamine prostaglandin E1 (PGE1) or alprostadil (Caverject
I notice none of these medications are listed in Goodrx. Does anyone know how much they cost? What some of the plusses and minuses are in their use? "The three main types of medications used in penile injection therapy include: papaverine phentolamine prostaglandin E1 (PGE1) or alprostadil (Caverject
cesces
in
Advanced Prostate Cancer
3 years ago
In need of advice 🙏🏻
Hi ladies, On my second round of ivf just been for baseline scan today and my lining was fine (which was what I was worried about as took over 4 weeks to thin my lining last time) however I had 2 large follicles on both ovaries. They said buserelin stimulates ovaries before it shuts them off and mine
Hi ladies, On my second round of ivf just been for baseline scan today and my lining was fine (which was what I was worried about as took over 4 weeks to thin my lining last time) however I had 2 large follicles on both ovaries. They said buserelin stimulates ovaries before it shuts them off and mine
ICSI2021
in
Fertility Network UK
3 years ago
Fixing the Microbiome - Fighting Pathogens?
I do a lot of things to help my brain and clean up a-synuclein in the gut (and hopefully the brain), but it seems to me that no protocol is complete unless it addresses normalizing the microbiome, and assuming that if there is some pathogen in the microbiome that started this cascade, addressing that
I do a lot of things to help my brain and clean up a-synuclein in the gut (and hopefully the brain), but it seems to me that no protocol is complete unless it addresses normalizing the microbiome, and assuming that if there is some pathogen in the microbiome that started this cascade, addressing that
Bolt_Upright
in
Cure Parkinson's
3 years ago
Panic Attack While Preaching
Hi, everyone. This Sunday, I was preaching from the pulpit and got some stage fright. I felt nauseous and butterfly-filled and started awkwardly pausing mid-sentence, taking large sips of water, and feeling my voice turn shaky. I am really worried. Have I chosen the wrong career path? Should I reconsider
Hi, everyone. This Sunday, I was preaching from the pulpit and got some stage fright. I felt nauseous and butterfly-filled and started awkwardly pausing mid-sentence, taking large sips of water, and feeling my voice turn shaky. I am really worried. Have I chosen the wrong career path? Should I reconsider
mvillarreal
in
Anxiety and Depression Support
3 years ago
Feeling guilty for calling in sick
Hi there. When my depression and anxiety roll around I often call into work sick. I can’t relax when I do call in, I just worry more about how I let my team down. How do you keep perspective and lessen your guilt?
Hi there. When my depression and anxiety roll around I often call into work sick. I can’t relax when I do call in, I just worry more about how I let my team down. How do you keep perspective and lessen your guilt?
Swimming5
in
Anxiety and Depression Support
3 years ago
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