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Docosahexaenoic acid enhances the treatment efficacy for CRPCa by inhibiting autophagy through Atg4B inhibition, 2024 Aug 23
Possible simple dietary intervention to increase autophagy in PCa and boost efficacy of ARSIs. Abstract & Intro (+ Section snippets in ScienceDirect link): * * * [u][i]
Abstract
[/i][/u] [i]
Autophagy induction in cancer is involved in cancer progression and the acquisition of resistance to
Possible simple dietary intervention to increase autophagy in PCa and boost efficacy of ARSIs. Abstract & Intro (+ Section snippets in ScienceDirect link): * * * [u][i]
Abstract
[/i][/u] [i]
Autophagy induction in cancer is involved in cancer progression and the acquisition of resistance to
cujoe
in
Fight Prostate Cancer
1 month ago
Lo-La
Hi. My husband has decompensated cirrhosis. He is 69. He has been visiting St. James’s hospital in Leeds for quite some time for a transplant assessment. He has been trying unsuccessfully to get fit enough to be listed for a transplant. He suffers from HE regularly and really struggles to take lactulose
Hi. My husband has decompensated cirrhosis. He is 69. He has been visiting St. James’s hospital in Leeds for quite some time for a transplant assessment. He has been trying unsuccessfully to get fit enough to be listed for a transplant. He suffers from HE regularly and really struggles to take lactulose
Zoe2022
in
British Liver Trust
1 month ago
Recent PGK1 and Terazosin Study
PGK1 and Terazosin has been discussed before on this site. A new study (link below) published on Aug 21st, 2024 The study, published Aug. 21 in Science Advances, presented evidence that PGK1 is a “rate-limiting” enzyme in energy production in the output-signaling branches, or axons, of the dopamine
PGK1 and Terazosin has been discussed before on this site. A new study (link below) published on Aug 21st, 2024 The study, published Aug. 21 in Science Advances, presented evidence that PGK1 is a “rate-limiting” enzyme in energy production in the output-signaling branches, or axons, of the dopamine
Mezmerric
in
Cure Parkinson's
1 month ago
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No Silver Bullet 4 PD's next Webinar "The importance of the gut-brain axis in Parkinson's"
We are delighted to announce that our next No Silver Bullet Zoom webinar will be taking place at
7.30pm London time on Monday, the 16th of September.
Dr Filip Scheperjans will be talking to us about
"The importance of the gut-brain axis in Parkinson's".
Please use the Eventbrite link
We are delighted to announce that our next No Silver Bullet Zoom webinar will be taking place at
7.30pm London time on Monday, the 16th of September.
Dr Filip Scheperjans will be talking to us about
"The importance of the gut-brain axis in Parkinson's".
Please use the Eventbrite link
Propertytyphoon
in
Cure Parkinson's
1 month ago
Masterful Overview of Dementia
Dr Robert Sapolsky just posted an authoritative and helpful talk on YouTube which looks at possible causes of Alzheimer's, prospective treatments, and practical steps to minimise one's risk.I found it a fascinating and entertaining video. It probably has some relevance to Parkinson's, but in any case
Dr Robert Sapolsky just posted an authoritative and helpful talk on YouTube which looks at possible causes of Alzheimer's, prospective treatments, and practical steps to minimise one's risk.I found it a fascinating and entertaining video. It probably has some relevance to Parkinson's, but in any case
00Mark
in
Cure Parkinson's
1 month ago
Blood results help
Hi I have had blood test tsh is one (range 0.4 to 5) and T4 is 14 ( range is 9 to 19). Also had an ultrasound which showed altered echotexture but no enlargement of thyroid. Are these results OK? Have symptoms of underactive thyroid but results all in range. Thanks
Hi I have had blood test tsh is one (range 0.4 to 5) and T4 is 14 ( range is 9 to 19). Also had an ultrasound which showed altered echotexture but no enlargement of thyroid. Are these results OK? Have symptoms of underactive thyroid but results all in range. Thanks
Lolly2564
in
Thyroid UK
6 months ago
Other blood results
I now have more results Serum folate 14.3 (3.1-17.5) Ferritin 138 (13-150) Iron 14 (5-28) B12 280 (200-940) Since they are in the range ‘everything is normal’! The coeliac one was clear so I can now try gluten free for 3 months to see if it makes any changes. But I am still tired, muscle aches
I now have more results Serum folate 14.3 (3.1-17.5) Ferritin 138 (13-150) Iron 14 (5-28) B12 280 (200-940) Since they are in the range ‘everything is normal’! The coeliac one was clear so I can now try gluten free for 3 months to see if it makes any changes. But I am still tired, muscle aches
Purple450
in
Thyroid UK
6 months ago
Elevated Testosterone
I was on Abiraterone and prednisone for 6 months until June 6, 2024. My blood work: 4/25/2024 Testosterone 44 ng/dL, PSA undetectable 5/28 T 35, PSA undetectable 6/6 Stopped Abiraterone 7/8 T 968 PSA 0.21 8/19 T 1475 PSA 0.54 My MO want's to do a PSMA scan in a month. I don't see
I was on Abiraterone and prednisone for 6 months until June 6, 2024. My blood work: 4/25/2024 Testosterone 44 ng/dL, PSA undetectable 5/28 T 35, PSA undetectable 6/6 Stopped Abiraterone 7/8 T 968 PSA 0.21 8/19 T 1475 PSA 0.54 My MO want's to do a PSMA scan in a month. I don't see
rainlessman
in
Advanced Prostate Cancer
1 month ago
Good news after SBRT
My last PSMA pet showed an 8mm prostate tumor in my left lung. My PSA before the radiation was 1.06. 2 weeks after radiation the PSA is <.06. I'm seeing my MO tomorrow to see if he will continue to hold off on ADT. Any suggestion/recommendations? Thanks
My last PSMA pet showed an 8mm prostate tumor in my left lung. My PSA before the radiation was 1.06. 2 weeks after radiation the PSA is <.06. I'm seeing my MO tomorrow to see if he will continue to hold off on ADT. Any suggestion/recommendations? Thanks
old64horn
in
Advanced Prostate Cancer
1 month ago
my son test today show prlactin very high
my sons blood test shown tsh 5.48 ]045-4.5] b12 363 [190-800] vitamin d 22 [50-100] but also prolactin is high 27.77[4.04-15.2] any body knows why his prolactin high pls
my sons blood test shown tsh 5.48 ]045-4.5] b12 363 [190-800] vitamin d 22 [50-100] but also prolactin is high 27.77[4.04-15.2] any body knows why his prolactin high pls
morcan54
in
Thyroid UK
1 month ago
Fibroscan result
Hi I had a fibroscan this morning and previously ayear ago my kpa was 23.5 and today it was 14.3 kpa..I haven't touched alcohol in 14 years but was told they will discuss it and decide if its non alcoholic or alcoholic category which totally confused me as I don't drink alcohol..I had a ultrasound 6
Hi I had a fibroscan this morning and previously ayear ago my kpa was 23.5 and today it was 14.3 kpa..I haven't touched alcohol in 14 years but was told they will discuss it and decide if its non alcoholic or alcoholic category which totally confused me as I don't drink alcohol..I had a ultrasound 6
Ringlet48
in
British Liver Trust
1 month ago
biopsy results
I have been diagnosed with Squamous cell lung cancer, I met with the respiratory doctor, who is booking me in for a pneumonectomy, has anyone had this procedure and can offer any advise
I have been diagnosed with Squamous cell lung cancer, I met with the respiratory doctor, who is booking me in for a pneumonectomy, has anyone had this procedure and can offer any advise
Hedgehog43
in
The Roy Castle Lung Cancer Foundation
1 month ago
Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models, Cinical Cancer Research, 2020 Dec 1
The following paper from 2020 might be of interest to those using the antiandrogen bicalutimide as a major component in their treatment programs. Much has been made of cancer cell death by ferroptosis and from this first paper it seems probable that there is some potential synergy between iron supplementation
The following paper from 2020 might be of interest to those using the antiandrogen bicalutimide as a major component in their treatment programs. Much has been made of cancer cell death by ferroptosis and from this first paper it seems probable that there is some potential synergy between iron supplementation
cujoe
in
Fight Prostate Cancer
1 month ago
new member
hi everyone l joined this group today was wondering could l get any advice, am 38 been recently diagnosed with underactive thyroid l am currently on 100mg of Lev tablets but l still feel tired l have put on so much weigh in past few years and didn’t know what was causing it, I have bought the semuglutide
hi everyone l joined this group today was wondering could l get any advice, am 38 been recently diagnosed with underactive thyroid l am currently on 100mg of Lev tablets but l still feel tired l have put on so much weigh in past few years and didn’t know what was causing it, I have bought the semuglutide
Preciouspearl
in
Thyroid UK
6 months ago
bloodshot eye and Graves
I got this today out of the blue. Going to have it checked tomorrow. I wonder if this is to do with Graves/TED? I’m currently on 2.5mg carbimazole.
I got this today out of the blue. Going to have it checked tomorrow. I wonder if this is to do with Graves/TED? I’m currently on 2.5mg carbimazole.
Kari55
in
Thyroid UK
1 month ago
Liver rebirth.
Have had a fatty liver for some years, doctors told me to lay off to allow the liver to recover. I have done dry January every year since 2013, but carried on drinking during the week in between. Recent blood tests (2024) showed high Gamma GT's (190iUL) and ALT's (81iUL) and a subsequent Fibroscan showed
Have had a fatty liver for some years, doctors told me to lay off to allow the liver to recover. I have done dry January every year since 2013, but carried on drinking during the week in between. Recent blood tests (2024) showed high Gamma GT's (190iUL) and ALT's (81iUL) and a subsequent Fibroscan showed
Hidden
in
British Liver Trust
1 month ago
Wednesday's Word
[i]
fibrosis
[/i] This refers to the development of scar tissue. Our body naturally wants to return our tissue and repair it to its normal structure. Most forms of
acute
liver injury, the liver will return it to its normal structure and size. If the injury is
chronic
, the rate
[i]
fibrosis
[/i] This refers to the development of scar tissue. Our body naturally wants to return our tissue and repair it to its normal structure. Most forms of
acute
liver injury, the liver will return it to its normal structure and size. If the injury is
chronic
, the rate
DonnaBoll
Administrator
in
PBC Foundation
1 month ago
Dad Diagnosed w/Advanced Prostate Cancer - PSA of 4800 - Question about biopsy?
Hello everyone! My name is Ashley and I set up an account here for my dad (60 years old) who has been recently diagnosed with advanced prostate cancer that has metastasized to the bones. I have been reading many of the posts on this website and have learned so much already. It has helped me reassure
Hello everyone! My name is Ashley and I set up an account here for my dad (60 years old) who has been recently diagnosed with advanced prostate cancer that has metastasized to the bones. I have been reading many of the posts on this website and have learned so much already. It has helped me reassure
Cew0303
in
Advanced Prostate Cancer
1 month ago
Lupus re-diagnosis UCTD
Hello All, so when I last posted I had been to the rheumatologist Prof X and told my bloods were not suggestive of lupus but he did not suggest want condition could be the underlying cause of my symptoms. This morning he chose not to see me, instead I saw a very nice female doctor in clinical research
Hello All, so when I last posted I had been to the rheumatologist Prof X and told my bloods were not suggestive of lupus but he did not suggest want condition could be the underlying cause of my symptoms. This morning he chose not to see me, instead I saw a very nice female doctor in clinical research
KeepingUpBeat
in
LUPUS UK
6 months ago
mildly heterogeneous parenchymal echotexture ultrasound results
First time having any abnormality on my ultrasound for PBC check up. I was diagnosed about 7 years ago labs mostly within normal range with slight elevations in liver function here and there. On urso, have bloating and a little weight gain. I am wondering if anyone has this result and did they feel
First time having any abnormality on my ultrasound for PBC check up. I was diagnosed about 7 years ago labs mostly within normal range with slight elevations in liver function here and there. On urso, have bloating and a little weight gain. I am wondering if anyone has this result and did they feel
Michiganpbc
in
PBC Foundation
1 month ago
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